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A Novel KIT INDEL Mutation in Acute Myeloid Leukemia With t(8;21)(q22;q22); RUNX1-RUNX1T1

Lee JH, Park C, Kim SH, Shin MG

No abstract available.
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Massive Upper Gastrointestinal Bleeding from Multiple Gastrointestinal Stromal Tumor in a Neurofibromatosis Patient

Kim SB, Chung WC

No abstract available.
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C-Kit-Negative Gastrointestinal Stromal Tumor in the Stomach

Seo HS, Hyeon JY, Shin OR, Lee HH

C-kit-negative gastrointestinal stromal tumors (GISTs) are uncommon, and there have been few reports about the diagnosis and treatment of c-kit-negative GISTs in the stomach. We report the case of a...
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A Case of an Extragastrointestinal Stromal Tumor of the Pelvic Cavity Presenting with Hematuria

Kwak MO, Jo SY, Kim JA, Lee HK, Lee HG

  • KMID: 2258908
  • Korean J Med.
  • 2011 Jun;80(Suppl 2):S295-S300.
Although gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor of the gastrointestinal tract, it also occurs in the non-gastrointestinal tract, and is referred to as extragastrointestinal stromal tumor...
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Malignant acanthosis nigricans in a patient with a gastrointestinal stromal tumor

Park KW, Lim DH, Lee SI

No abstract available.
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Analysis of c-Kit Gene Polymorphism in NK/T Cell Lymphoma in Korean Population

Kim HJ, Baek SK, Jung KY, Lee SH, Kwon SY, Choi HY

  • KMID: 1597347
  • Korean J Otolaryngol-Head Neck Surg.
  • 2005 May;48(5):641-645.
BACKGROUND AND OBJECTIVES: The proto-oncogene c-KIT encodes a receptor tyrosine kinase (KIT) whose ligand is a stem cell factor. KIT is expressed and critical for the development and growth of...
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De novo Leukemic Variant of Mast Cell Leukemia With KIT D816V

Bang HI, Park R, Park ES, Choi IH, Kim KH, Shin JW, Choi TY, Han K, Won JH

No abstract available.
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KIT/PDGFRA Expression and Mutation in Testicular Seminoma and Ovarian Dysgerminoma

Choi SY, Suh KS, Kim YB, Lee HJ, Kim ES, Park MJ

BACKGROUND: KIT and PDGFRA are tyrosine kinase receptors. Stem cell factor/KIT-mediated signaling plays a role in normal spermatogenesis, and the alteration of KIT is important in the pathogenesis of seminomas/dysgerminomas...
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c-kit and Ligand Expression in the Mouse Hippocampus after Kainate-induced Seizure

Hong HN, Lee JH, Jung TJ, Kim DH

  • KMID: 1529446
  • Korean J Anat.
  • 1997 Feb;30(1):87-98.
In the present study, we have etamined the role of c-kit and KL ligand in the mouse brain after kainate-induced seizure. To investigate whether c-kit receptor and KL ligand might...
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Clinical Significance of c-kit Protein Expression and c-kit Gene Mutation in Nasopharyngeal Cancer

Kang IG, Lee SH, Jung KY, Woo JS, Baek SK, Cho SH, Lee SW, Kwon SY, Kim IS

  • KMID: 2276770
  • Korean J Otolaryngol-Head Neck Surg.
  • 2007 Jun;50(6):519-524.
BACKGROUND AND OBJECTIVES: The proto-oncogene c-kit is a receptor tyrosine kinase recognized to initiate essential signal transduction pathways that transmit biological signals for cellular proliferation, differentiation and metastasis. Aberrant expression...
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Hemoperitoneum Caused by a Spontaneously Ruptured Gastrointestinal Stromal Tumor with Cystic Degeneration

Lee JH

A 39-year-old man visited Soonchunhyang University Gumi Hospital with abdominal pain. Abdominal computed tomography showed a large heterogeneously enhancing mass abutting the stomach body and a large amount of fluid...
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Expression of Epidermal c-Kit+ of Vitiligo Lesions Is Related to Responses to Excimer Laser

Park OJ, Han JS, Lee SH, Park CS, Won CH, Lee MW, Choi JH, Chang SE

BACKGROUND: The survival and growth of melanocytes are controlled by the binding of stem cell factor to its cell surface receptor c-kit+ (CD117). We have observed that c-kit+ melanocytes existed...
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Primary Extragastrointestinal Stromal Tumor (EGIST) of the Greater Omentum

Choi KU, Kim JY, Park DY, Lee CH, Sol MY, Suh KS, Lee JW

  • KMID: 1725824
  • Korean J Pathol.
  • 2001 Aug;35(4):347-350.
Gastrointestinal stromal tumors (GISTs) were recently defined as spindle cell, epithelioid, or occasionally, pleomorphic mesenchymal tumors of the gastrointestinal tract that express the CD117 (proto-oncogene c-kit protein, stem cell...
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Immunohistochemical Expression of CD117, CD34, Vimentin and alpha-Smooth Muscle Actin in Gastrointestinal Stromal Tumors

Kim JK, Kwon OJ, Kim BH

  • KMID: 2275590
  • Korean J Pathol.
  • 2001 Dec;35(6):506-512.
BACKGROUND: The interstitial cell of Cajal (ICC), the cell of origin for gastrointestinal stromal tumor (GIST), expresses CD117 (c-kit) which is a receptor for KIT ligand in cell membranes. It...
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c-kit Receptor and Ligand Expression in Developing Nervous System Blocked c-kit Function by ACK2

Hong H, Lee J, Kim D

  • KMID: 2092663
  • Korean J Anat.
  • 1998 Aug;31(4):619-628.
The objective of the present study was to investigate the expression of KL ligand and synaptophysin during postnatal development of the cerebellum blocked c-kit function by ACK2 to determine whether...
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Extra-Gastrointestinal stromal tumor of the pancreas with c-KIT gene mutation: Report of a case

Kim ST, Paik KY, Chung JC, Choi DW

  • KMID: 1928363
  • Korean J Hepatobiliary Pancreat Surg.
  • 2007 Mar;11(1):63-66.
Mesenchymal tumors of the pancreas are quite rare, accounting for less than 1% of all pancreatic tumors. Mesenchymal tumors in the gastrointestinal tract are mainly gastrointestinal stromal tumors (GISTs). GISTs...
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A case of exophytic pedunculated gastrointestinal stromal tumor with cystic changes

Kim SW, Cha SC, Cho YJ, Park HK, Park SK, Kang HJ

  • KMID: 2142940
  • Korean J Med.
  • 2010 Feb;78(2):222-225.
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract, and cystic changes are commonly observed. However, there have been few reports of cases of exophytic...
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Expression and Mutational Analysis of c-kit in Ovarian Surface Epithelial Tumors

Kim DJ, Lee MH, Park TI, Bae HI

Coexpression of Kit ligand and c-kit has been reported in some gynecologic tumors. To determine whether imatinib mesylate is useful in ovarian epithelial tumors, we performed immunohistochemical and mutational analysis....
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Roles of Stem Cell Factor and c-kit Receptor in the Development of Cerebellar GABAergic Neurons

Won YJ, Lee JH, Im JO, Yun SY, Hwang SJ, Kim D, Hong HN

  • KMID: 2092844
  • Korean J Anat.
  • 2004 Oct;37(5):481-490.
Evidence that Stem cell factor (SCF) and c-Kit receptor tyrosine kinase are expressed in the cerebellum during postnatal development, suggests a possible contribution of the SCF/Kit signaling pathway in the...
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Mutation-Free Expression of c-Kit and PDGFRA in Phyllodes Tumors of the Breast

Jung CW, Suh KS, Lee JS, Kim JR, Chang ES, Sul HJ, Park MJ

  • KMID: 2425144
  • J Breast Cancer.
  • 2010 Sep;13(3):257-266.
PURPOSE: Phyllodes tumors (PTs) of the breast have been classified as benign, borderline, or malignant based on their histopathologic features. However, predicting clinical behavior based on these features has proven...
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