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A clinical effect of retreatment by prothionamide, cycloserine, para-aminosalicylic acid, streptomycin(kanamycin or tuberactinomyc-in) on pulmonary tuberculosis

Shin CS, Im YJ, Kim YJ, Koh SS, Kim MS

  • KMID: 1699816
  • Tuberc Respir Dis.
  • 1992 Apr;39(2):167-171.
No abstract available.
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An Evaluation of Short-term Isoprodian Treatment in Leprosy

Park SD, Kim YP

  • KMID: 2039164
  • Korean J Dermatol.
  • 1977 Sep;15(3):267-277.
Twenty-three bacteriologically positive leprosy patients were randomly selected from a leprosarium, randomly divided into four treatment groups, and given vaying dosages of Isoprodian, the tablet contained INAH 175mg, Prothionamide 175mg...
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A Case of Prothionamide Induced Hepatitis on Patient with Multi-Drug Resistant Pulmonary Tuberculosis

Park JB, Park BH, Son JY, Jung JY, Kim EY, Lim JE, Lee SH, Lee SK, Kim SY, Jung W, Lim S, Lee KJ, Kang YA, Kim YS, Kim SK, Chang J, Choi J, Park MS

The prevalence of multi-drug resistant tuberculosis (MDR-TB), which is resistant to isoniazid and rifampin, has been increasing in Korea. And the side effects of 2nd line anti-tuberculosis medications, including drug-induced...
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Correlation between GenoType MTBDRplus Assay and Phenotypic Susceptibility Test for Prothionamide in Patients with Genotypic Isoniazid Resistance

Lee JH, Jo KW, Shim TS

BACKGROUND: The purpose of this study was to analyze the relationship between the gene mutation patterns by the GenoType MTBDRplus (MTBDRplus) assay and the phenotypic drug susceptibility test (pDST) results...
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Medical Treatment of Pulmonary Multidrug-Resistant Tuberculosis

Shim TS, Jo KW

Treatment of multidrug-resistant tuberculosis (MDR-TB) is challenging because of the high toxicity of second-line drugs and the longer treatment duration required compared with drug-susceptible TB. The efficacy of treatment for...
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Diagnosis and Treatment of Multidrug-Resistant Tuberculosis

Shim TS

Despite global efforts to control tuberculosis (TB), multidrug-resistant TB (MDR-TB) is still a serious problem worldwide. The diagnosis of MDR-TB is based on mycobacterial culture followed by drug susceptibility testing,...
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A Case of Disseminated Multidrug-Resistant Tuberculosis involving the Brain

Jung EK, Chang JY, Lee YP, Chung MK, Seo EK, Koo HS, Choi HJ

We report a case of a 23-year-old female immigrant from China who was diagnosed with multidrug-resistant tuberculosis affecting her lung and brain, resistant to the standard first-line therapeutics and streptomycin....
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A Clinical Effect of Ofloxacin, Prothionamide, Cycloserine Streptomycin (Kanamycin or Tuberactinomycin) in Retreatment of Pulmonary Tuberculosis

Song JY, Yoo MK, Hong JR, Man Jeong , Kim YJ, Kim MS

  • KMID: 2317909
  • Tuberc Respir Dis.
  • 1995 Jun;42(3):295-301.
BACKGROUND: The serious problems in retreatment of pulmonary tuberculosis are a significant proportion of drug resistance. Preferably retreatment should contain the drugs which has never used before, so drug retreatment...
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Low Serum Concentrations of Moxifloxacin, Prothionamide, and Cycloserine on Sputum Conversion in Multi-Drug Resistant TB

Lee SH, Seo KA, Lee YM, Lee HK, Kim JH, Shin C, Ghim JR, Shin JG, Kim DH

PURPOSE: Low serum concentrations of drugs used to treat multi-drug resistant tuberculosis (MDR-TB) have occasionally been associated with treatment failure. We determined the frequencies of low serum concentrations of anti-MDR-TB...
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An Analysis of Antituberculosis Drug Susceptibility Test Results in Kyung Hee Medical Center During Recent Four years

Kim JH, Suh JT, Kim MH, Kim GY, Her SR, Lee HJ, Lee WI, Kang SY

  • KMID: 1892735
  • Korean J Clin Microbiol.
  • 2004 Sep;7(2):182-185.
BACKGROUND: Tuberculosis is still one of the most seriously threatening infections in Korea, because of multidrug resistant tuberculosis. Results of antituberculosis drug susceptibility test can provide clinicians very important informations...
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Usefulness of flexible bronchoscopy in children with suspected pulmonary tuberculosis who have difficulty in sputum expectoration

Lee HJ, Park Y, Yang EA, Kim HS, Chun YH, Yoon JS, Kim HH, Kim JT

PURPOSE: To assess the usefulness of flexible bronchoscopy in patients with suspected pulmonary tuberculosis (PTB) who have difficulty in sputum expectoration. METHODS: The subjects of this study were patients who were...
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Comparison of Anti-mycobacterial Drug Susceptibility Test Results by Institutes and Methods

Oh SH, Kim YJ, Park SK, Hwang SH, Kim HH, Lee EY, Chang CL

BACKGROUND: The purposes of the current study were to evaluate the concordant rates of anti-mycobacterial drug susceptibility test (DST) results in different solid media performed in different institutes, and to...
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Pharmacokinetics of ofloxacin in Patients with Multidrug-Resistant Tuberculosis

Park SK, Yoon YR, Lee WC, Jun HM, Shon JH, Kim KA, Park JY, Shin JG

BACKGROUND: There are few studies that have reported on the pharmacokinetic(PK) disposition of fluoroquinolones in patients with multi-drug resistant tuberculosis(MDR-Tb), even though fluoroquinolones are frequentl y co-prescribed to those patients....
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The Fate of Intractable Tuberculosis Cases Under National Tuberculosis Programme

Lew WJ, Lee EG, Kwon DW, Kim SJ, Hong YP, Kim JB

BACKGROUND: The natural history of bacillary tuberculosis was studied in India and results showed that at the end of the 5-year period, 49% of the patients were dead, 33% were...
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Clinical Effects of Prothinoamide, Cycloserine, Para-Aminosalicylic Acid, Ofloxasine in Retreatment of Pulmonary Tuberculosis

Hong JR, Yoo MK, Jeong JM, Kim YJ, Son MH

BACKGROUND: Antituberculous therapy is set a short-term therpy used isoniazid(INH), rifampin(RFP), ethambutol(EMB), pyrazinamide(PZA) from 1970s' and treatment rate has been very improved. But drug interruption or irregular medication due to...
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The survey for clinical course of intractable pulmonary tuberculosis

Choi SI, Lee J, Kong SJ, Park JH

  • KMID: 2081166
  • Korean J Med.
  • 2005 Dec;69(6):590-600.
BACKGROUND: Although various standard anti-tuberculosis chemotherapy regimens were suggested by World Health Organization in pulmonary tuberculosis, as yet, treatment regimen has not been established in intractable pulmonary tuberculosis. Also those...
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