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Heat shock protein 27 interacts with vimentin and prevents insolubilization of vimentin subunits induced by cadmium

Lee JS, Zhang MH, Yun EK, Geum D, Kim K, Kim TH, Lim YS, Seo JS

  • KMID: 1089452
  • Exp Mol Med.
  • 2005 Oct;37(5):427-435.
Vimentin is an intermediate filament that regulates cell attachment and subcellular organization. In this study, vimentin filaments were morphologically altered, and its soluble subunits were rapidly reduced via cadmium chloride...
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Gold compound auranofin inhibits I kappaB kinase (IKK) by modifying Cys-179 of IKK beta subunit

Jeon KI, Byun MS, Jue DM

  • KMID: 1097252
  • Exp Mol Med.
  • 2003 Apr;35(2):61-66.
Antirheumatic gold compounds have been shown to inhibit NF-kB activation by blocking IkB kinase (IKK) activity. To examine the possible inhibitory mechanism of gold compounds, we expressed wild type and...
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In silico analysis of an envelope domain III-based multivalent fusion protein as a potential dengue vaccine candidate

Fahimi H, Sadeghizadeh M, Mohammadipour M

PURPOSE: Dengue virus infection is now a global problem. Currently, there is no licensed vaccine or proven antiviral treatment against this virus. All four serotypes (1-4) of dengue virus can...
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A Case of Atypical McCune-Albright Syndrome Associated with Hyperthyroidism and Hypersecretion of Growth Hormone

You MB, Kang KH, Lee BS, Chae EH, Kim MC, Jung JI, Park SH, Lee HJ, Jung ST

  • KMID: 2200390
  • J Korean Soc Endocrinol.
  • 2003 Aug;18(4):426-432.
McCune-Albright syndrome is characterized by polyostotic fibrous dysplasia, Caf -au-lait pigmentation and precocious puberty or other endocrinopathy. It can be caused by substitution of His, Cys or Gly for Arg...
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Genetic Diversity of Taenia asiatica from Thailand and Other Geographical Locations as Revealed by Cytochrome c Oxidase Subunit 1 Sequences

Anantaphruti MT, Thaenkham , Watthanakulpanich D, Phuphisut , Maipanich , Yoonuan T, Nuamtanong S, Pubampen S, Sanguankiat S

Twelve 924 bp cytochrome c oxidase subunit 1 (cox1) mitochondrial DNA sequences from Taenia asiatica isolates from Thailand were aligned and compared with multiple sequence isolates from Thailand and 6...
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Expression of NAD(P)H Oxidase Subunits and Their Contribution to Cardiovascular Damage in Aldosterone/Salt-Induced Hypertensive Rat

Park YM, Lim BH, Touyz RM, Park JB

NAD(P)H oxidase plays an important role in hypertension and its complication in aldosterone-salt rat. We questioned whether NAD(P)H oxidase subunit expression and activity are modulated by aldosterone and whether this...
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Cardiac Hypertrophy in Transgenic Mice with Overexpressed Small-Subunit of Human Myosin Light Chain Phosphatase

Bae SW, Lee WH, Kim CH, Park HK, Lee SC, Ko YH, Park SW, Arimura T, Kimura A, Park JE

BACKGROUND AND OBJECTIVES: Recent reports have demonstrated that perturbation of the balance between myo-sin light chain (MLC) phosphorylation and the dephosphorylation status is associated with the development of cardiac hypertrophy....
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Hypoxia-inducible factor (HIF-1)alpha: its protein stability and biological functions

Lee JW, Bae SH, Jeong JW, Kim SH, Kim KW

  • KMID: 755659
  • Exp Mol Med.
  • 2004 Feb;36(1):1-12.
Hypoxia-inducible factor (HIF-1) is an oxygen-dependent transcriptional activator, which plays crucial roles in the angiogenesis of tumors and mammalian development. HIF-1 consists of a constitutively expressed HIF-1beta subunit and one...
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Molecular Characterization of Taenia multiceps Isolates from Gansu Province, China by Sequencing of Mitochondrial Cytochrome C Oxidase Subunit 1

Li WH, Jia WZ, Qu ZG, Xie ZZ, Luo JX, Yin H, Sun XL, Blaga R, Fu BQ

A total of 16 Taenia multiceps isolates collected from naturally infected sheep or goats in Gansu Province, China were characterized by sequences of mitochondrial cytochrome c oxidase subunit 1 (cox1)...
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Partial Purification and Properties of a Cysteine Protease from Citrus Red Mite Panonychus citri

Hong SC, Her KH, Kim HU, Lee J, Lee SP, Chung YB

Several studies have reported that the citrus red mites Panonychus citri were an important allergen of citrus-cultivating farmers in Jeju Island. The aim of the present study was to purify...
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Gene Expression of Somatostatin Receptor (Subtype 2 & 5), Gi2 alpha and Pit-1 in GH-secreting Pituitary Adenomas

Ryu MS, Yang IM, Park CY, Woo JT, Kim SW, Kim JW, Kim YS, Choi YK, Kim EH, Park SJ, Kim KG

  • KMID: 2199901
  • J Korean Soc Endocrinol.
  • 2002 Apr;17(2):158-169.
BACKGROUND: Mutation of Gs protein subunit (gsp oncogene), detected in about 30~40% of growth hormone (GH)-secreting pituitary tumors, is associated with an increased long-acting somatostatin analog octreotide sensitivity. However, the...
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Role of Oxygen Free Radical in the Expression of Interleukin-8 andInterleukin-1beta Gene in Mononuclear Phagocytic Cells

Kang MJ, Kim JY, Park JS, Lee SJ, Yoo CG, Kim YW, Han SK, Shim YS

  • KMID: 2317955
  • Tuberc Respir Dis.
  • 1995 Dec;42(6):862-870.
BACKGROUND: Oxygen free radicals have generally been considered as cytotoxic agents. On the other hand, recent results suggest that small nontoxic amounts of these radicals may act a role in...
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Use of Cytochrome c Oxidase Subunit I (COI) Nucleotide Sequences for Identification of the Korean Luciliinae Fly Species (Diptera: Calliphoridae) in Forensic Investigations

Park SH, Zhang Y, Piao H, Yu DH, Jeong HJ, Yoo GY, Chung U, Jo TH, Hwang JJ

Blowflies, especially species belonging to the subfamily Luciliinae, are the first insects to lay eggs on corpses in Korea. Fast and accurate species identification has been a key task for...
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Protective Effects of Gabapentin on Allodynia and alpha2delta1-Subunit of Voltage-dependent Calcium Channel in Spinal Nerve-Ligated Rats

Hahm TS, Ahn HJ, Bae CD, Kim HS, Lim SW, Cho HS, Lee SM, Sim WS, Kim JA, Gwak MS, Choi SJ

This study was designed to determine whether early gabapentin treatment has a protective analgesic effect on neuropathic pain and compared its effect to the late treatment in a rat neuropathic...
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