- Increased expression of Galphaq protein in the heart of streptozotocin-induced diabetic rats
-
Yang JM, Cho CH, Kong KA, Jang IS, Kim HW, Juhnn YS
- KMID: 1029924
- Exp Mol Med.
- 1999 Dec;31(4):179-184.
Heart disease is one of the major cause of death in diabetic patients, but the thogenesis of diabetic cardio-myopathy remains unclear. In this experiment, to sess the significance... -
- CITED
-
- Close
- SHARE
-
- Close
- Nucleolus contains signal molecules that constitute membrane-nucleolus linked pathway
-
Jeong JS, Kim IH, Lee HJ, Choi YC
- KMID: 755010
- Exp Mol Med.
- 1998 Dec;30(4):205-213.
Since there have been very few studies on nucleolar signaling, an attempt was made to establish nucleolar signal pathways which link the cell membrane to the nucleolus for the transfer... -
- CITED
-
- Close
- SHARE
-
- Close
- Major house dust mite allergen, Der p I, activates phospholipase D in human peripheral blood mononuclear cells from allergic patients: involvement of protein kinase C
-
Oh JW, Kim JH, Lee KS, Han JS
- KMID: 1109304
- Exp Mol Med.
- 2000 Jun;32(2):67-71.
The major house-dust-mite allergen, Der p I, stimulates the phospholipase D (PLD) in peripheral blood mononuclear cells (PBMC) from allergic patients with maximal responses after 30 min exposure. At 30... -
- CITED
-
- Close
- SHARE
-
- Close
- Involvement of JNK-initiated p53 accumulation and phosphorylation of p53 in pseudolaric acid B induced cell death
-
Gong X, Wang M, Tashiro SI, Onodera S, Ikejima T
- KMID: 1110127
- Exp Mol Med.
- 2006 Aug;38(4):428-434.
A terminal deoxynucleotidyl transferase-mediated dUTP nick end-labeling (TUNEL) assay was used to determine that apoptosis causes HeLa cell death induced by pseudolaric acid B. The c-Jun N-terminal kinase (JNK) inhibitor... -
- CITED
-
- Close
- SHARE
-
- Close
- Effects of Scutellarin on MUC5AC Mucin Production Induced by Human Neutrophil Elastase or Interleukin 13 on Airway Epithelial Cells
-
Jiang DP, Perelman J, Kolosov VP, Zhou XD
- KMID: 1785964
- J Korean Med Sci.
- 2011 Jun;26(6):778-784.
- doi: 10.3346/jkms.2011.26.6.778
Scutellarin is a flavonoid extracted from a traditional Chinese herb, Erigeron breviscapus. The present study investigated the effect of scutellarin on MUC5AC mucin production and the possible mechanism. Human bronchial... -
- CITED
-
- Close
- SHARE
-
- Close
- Involvement of betaPIX in angiotensin II-induced migration of vascular smooth muscle cells
-
Shin EY, Lee CS, Park MH, Kim DJ, Kwak SJ, Kim EG
- KMID: 756231
- Exp Mol Med.
- 2009 Jun;41(6):387-396.
- doi: 10.3858/emm.2009.41.6.044
Angiotensin II (Ang II) stimulates migration of vascular smooth muscle cell (VSMC) in addition to its contribution to contraction and hypertrophy. It is well established that Rho GTPases regulate cellular... -
- CITED
-
- Close
- SHARE
-
- Close
- Differential effects of Fas cross-linking on phospholipase D activation and related lipid metabolism in Fas-resistant A20 cells.
-
Lim SY, Lee SC, Shin IC, Han JS
- KMID: 1380228
- Exp Mol Med.
- 2002 Jul;34(3):201-210.
A20 murine lymphoma cells undergoing Fas-mediated apoptosis showed increase in the activity of phospholipase D (PLD), which is involved in proliferative or mitogenic cellular responses. Using A20 cell lines that... -
- CITED
-
- Close
- SHARE
-
- Close
- Caveolin-1 upregulation in senescent neurons alters amyloid precursor protein processing
-
Kang MJ, Chung YH, Hwang CI, Murata M, Fujimoto T, Mook-Jung , Cha CI, Park WY
- KMID: 1111405
- Exp Mol Med.
- 2006 Apr;38(2):126-133.
Lipid rafts provide a platform for regulating cellular functions and participate in the pathogenesis of several diseases. However, the role of caveolin-1 in this process has not been elucidated definitely... -
- CITED
-
- Close
- SHARE
-
- Close
- Activation of PKCdelta by tyrosine phosphorylation in rat parotid acinar cells
-
Benes C, Zheng Y, Soltoff SP
- KMID: 1026946
- J Korean Med Sci.
- 2000 Aug;15(Suppl):S40-S41.
- doi: 10.3346/jkms.2000.15.S.S40
Receptor- and nonreceptor-mediated stimuli produce increases in both PKCdelta tyrosine phosphorylation and activity in rat parotid acinar cells and other cells. In vivo and in vitro increases and decreases in... -
- CITED
-
- Close
- SHARE
-
- Close
- High Activities of Protein Kinases C and M in Fresh Human Stomach and Breast Tumors
-
Lim IK, Lee DJ, Lee KH, Yun TK
- KMID: 1095740
- Yonsei Med J.
- 1987 Dec;28(4):255-260.
- doi: 10.3349/ymj.1987.28.4.255
The activities of Ca+2-PL dependent protein Kinase (PKC) and independent protein kinase(RKM) were measured in human stomach and breast tumors and in the respective counterparts of normal tissue. Expression of... -
- CITED
-
- Close
- SHARE
-
- Close
- Infarct Size-limiting Effect of Calcium Preconditioning in Rabbit Hearts
-
Kim HD
- KMID: 2157647
- J Korean Med Sci.
- 2003 Jun;18(3):337-343.
- doi: 10.3346/jkms.2003.18.3.337
Recent studies demonstrated that brief period of Ca2+ depletion and repletion (Ca2+ preconditioning, CPC) has strong protective effects against ischemia in a rat heart. CPC and classic preconditioning (IPC) were... -
- CITED
-
- Close
- SHARE
-
- Close
- NADPH oxidase activation contributes to native low-density lipoprotein-induced proliferation of human aortic smooth muscle cells
-
Park IH, Hwang HM, Jeon BH, Kwon HJ, Hoe KL, Kim YM, Ryoo S
- KMID: 2155422
- Exp Mol Med.
- 2015 Jun;47(6):e168.
- doi: 10.1038/emm.2015.30
Elevated plasma concentration of native low-density lipoprotein (nLDL) is associated with vascular smooth muscle cell (VSMC) activation and cardiovascular disease. We investigated the mechanisms of superoxide generation and its contribution... -
- CITED
-
- Close
- SHARE
-
- Close
- Evidence of protein kinase C translocation by ischemic preconditioning in global ischemia model
-
Kim H, Kim DJ, Chung HS, Shim SJ, Yoo UH, Rah BJ, Kim HD
- KMID: 645205
- J Korean Med Sci.
- 1998 Oct;13(5):473-482.
- doi: 10.3346/jkms.1998.13.5.473
We tested recent evidence that ischemic preconditioning (PC) involves in translocation of protein kinase C (PKC) from the cytosol to myocyte membrane. Isolated Langendorff-perfused rabbit hearts (n=96) were subjected... -
- CITED
-
- Close
- SHARE
-
- Close
- Suppression of ROS generation by 4,4'-diaminodiphenylsulfone in non-phagocytic human diploid fibroblasts
-
Cho SC, Rhim JH, Son YH, Lee SJ, Park SC
- KMID: 946655
- Exp Mol Med.
- 2010 Mar;42(3):223-232.
- doi: 10.3858/emm.2010.42.3.024
The action mode of 4,4'-diaminodiphenylsulfone (DDS) is still under debate, although it has long been used in treatment of several dermatologic diseases including Hansen's disease. In this study, we tested... -
- CITED
-
- Close
- SHARE
-
- Close
- Characterization of yeast deoxyhypusine synthase: PKC-dependent phosphorylation in vitro and functional domain identification
-
Kang KR, Chung SI
- KMID: 1029929
- Exp Mol Med.
- 1999 Dec;31(4):210-216.
The biosynthesis of hypusine [Nepsilon-(4-amino-2-hydroxybutyl)-lysine] occurs in the eIF-5A precursor protein through two step posttranslational modification involving deoxyhypusine synthase which catalyzes transfer of the butylamine moiety of... -
- CITED
-
- Close
- SHARE
-
- Close
