- Degradation of immunoglobulins, protease inhibitors, and interleukin-1 by a secretory proteinase of Acanthamoeba castellanii
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Na BK, Cho JH, Song CY, Kim TS
- KMID: 1720411
- Korean J Parasitol.
- 2002 Jun;40(2):93-99.
- doi: 10.3347/kjp.2002.40.2.93
The effect of a secretory proteinase from the pathogenic amoebae Acanthamoeba castellanii on hosts defense-oriented or regulatory proteins such as immunoglobulins, interleukin-1, and protease inhibitors was investigated. The enzyme was... -
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- The Therapeutic Approaches for Hepatitis C Virus: Protease Inhibitors and Polymerase Inhibitors
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Kwo PY, Vinayek R
- KMID: 2284229
- Gut Liver.
- 2011 Dec;5(4):406-417.
The current standard of care for hepatitis C infection is peginterferon/ribavirin (PegIFN/RBV). We are entering the era where direct-acting antiviral agents (DAAs) will be added to PegIFN/RBV, leading to higher... -
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- Activation of Eosinophils with Airborne Fungi
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Shin SH, Kim JK, Kita H
- KMID: 2276174
- Korean J Otolaryngol-Head Neck Surg.
- 2004 Jun;47(6):549-553.
BACKGROUND AND OBJECTIVES: Allergic fungal sinusitis is characterized by allergic mucin which includes eosinophils and fungal hyphae. But we don't know why eosinophils are accumulated at the nasal secretion and... -
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- The Management of HCV Recurrence after Liver Transplantation
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Choi Y, Lee KW
- KMID: 2324075
- J Korean Soc Transplant.
- 2013 Jun;27(2):37-41.
Liver transplantation (LT) for hepatitis C virus (HCV)-related liver diseases has been increasing in Korea. HCV recurrence, a serious complication after LT, can accelerate liver cirrhosis and fatal graft loss.... -
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- Monomorphic ventricular tachycardia due to protease inhibitor intoxication by atazanavir
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Kim B, Kim KS
- KMID: 2416926
- Clin Exp Emerg Med.
- 2018 Jun;5(2):131-134.
- doi: 10.15441/ceem.17.229
Atazanavir is a protease inhibitor approved for use in combination with other antiretroviral drugs for the treatment of human immunodeficiency virus infection. Atazanavir and other protease inhibitors can sometimes induce... -
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- The Comparison of Parathyroid Hormone Degradation Effect by Various Protease Inhibitors in Blood Specimen
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Kim YS, Kwon HJ, Lee HK
- KMID: 854965
- Korean J Lab Med.
- 2009 Apr;29(2):104-109.
- doi: 10.3343/kjlm.2009.29.2.104
BACKGROUND: The objective of this study was to evaluate the role of proteases on the degradation of parathyroid hormone (PTH) in blood samples. METHODS: Protease inhibitors with specificity against serine... -
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- Changing patterns of Pancreatic enzyme after Distal Gastrectomy and the Effect of Protease Inhibitor Treatment
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Oh ST, Kim WS, Kim BS
- KMID: 2206235
- J Korean Surg Soc.
- 1997 Jun;52(6):846-851.
We have reported that serum amylase and lipase level elevate immediately after total gastrectomy independent to whether the pancreas is manipulated or not. Although we found high levels of amylase... -
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- Protease from Airborn Fungi Induce Activation of Nasal Epithelial Cells
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Shin SH, Park GU, Jeon CH
- KMID: 2037116
- Korean J Otolaryngol-Head Neck Surg.
- 2005 Feb;48(2):189-194.
BACKGROUND AND OBJECTIVES: The nasal epithelium is the first barrier encountered by airborne allergens and an active participant in airway inflammation. Fungi have been increasingly recognized as important pathogens in... -
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- Protease Inhibitor Treatment of Disseminated Intravascular Coagulation Associated with Aortic Dissection
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Ko SM, Kim N, Kim C, Cho JH, Lee EY, Huh K, Kim DK
- KMID: 2264250
- Korean J Med.
- 2012 Mar;82(3):341-346.
Disseminated intravascular coagulation (DIC) is a rare complication of aortic dissection. We report an unusual case of a 64-year-old woman with DIC associated with chronic aortic dissection who developed catastrophic... -
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- Calpain inhibitors reduce the cornified cell envelope formation by inhibiting proteolytic processing of transglutaminase 1
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Kim SY, Bae CD
- KMID: 755018
- Exp Mol Med.
- 1998 Dec;30(4):257-262.
Calpain I (mu-calpain) and II (m-calpain) are well known calcium-activated neutral cysteine proteases. Many reports have shown that activation of calpain is related to cataract formation, neuronal degeneration, blood clotting, ... -
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- New treatments for chronic hepatitis C
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Jang JY, Chung RT
- KMID: 1717320
- Korean J Hepatol.
- 2010 Sep;16(3):263-277.
- doi: 10.3350/kjhep.2010.16.3.263
Treatments for chronic hepatitis C has evolved significantly in the past 15 years. The standard of care (SOC) is peginterferon alfa-2a/-2b with ribavirin for 48 weeks or 24 weeks in... -
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- Change of Lymphocyte Subsets of HIV-Infected Asymptomatic Persons Administrated with Korean Red Ginseng
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Choi BS, Park YK, Kee MK, Cho OH, Lee YW, Shin YO
- KMID: 2204570
- J Korean Soc Virol.
- 1997 Mar;27(1):97-104.
For 16 years after the finding of HIV as an agent of AIDS in 1981, HIV therapeutic drugs of reverse transcriptase inhibitors (AZT, ddI, ddC, d4T) and protease inhibitors have... -
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- Emerging Therapies for Hepatitis C
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Kim DY, Ahn SH, Han KH
- KMID: 2070056
- Gut Liver.
- 2014 Sep;8(5):471-479.
- doi: 10.5009/gnl14083
The combination of pegylated interferon (PEG-IFN) and ribavirin (RBV), the current therapy for hepatitis C virus (HCV) infection, has saved the lives of many HCV-infected patients. Direct-acting antivirals (DAAs) target... -
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- Thrombosis in Patients with Acquired Immunodeficiency Syndrome
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Lee J, Park WB, Choe KW
- KMID: 2170221
- Infect Chemother.
- 2007 Dec;39(6):338-341.
Patients with HIV infection may be at increased risk of thrombosis. A variety of mechanism have been proposed to account for hypercoagulability in HIV-infected patients. These include decreased plasma concentrations... -
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- Expression of Maspin in Squamous Cell Carcinoma of the Head and Neck
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Chun JH, Park IS, Rho YS, Lim HJ, Kim DH
- KMID: 2141366
- Korean J Otolaryngol-Head Neck Surg.
- 2002 Nov;45(11):1086-1091.
Squamous cell carcinomas (SCCs) of the head and neck are malignant tumors with their ability to invade and metastasis, which can affect the prognosis. The molecular pathogenesis of SCC of... -
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- Recent Advances in Management of Acute Pancreatitis
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Lee JK
- KMID: 2373328
- Korean J Gastroenterol.
- 2015 Sep;66(3):135-143.
- doi: 10.4166/kjg.2015.66.3.135
Acute pancreatitis is common but remains a condition with significant morbidity and mortality. Despite a better understanding of the pathophysiology of acute pancreatitis achieved during the past few decades, there... -
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- Ceramide-Induced Apoptosis in Cultured Keratocyte
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Park HR, Kim TI, Tchah HW
- KMID: 2125617
- J Korean Ophthalmol Soc.
- 2003 Apr;44(4):945-954.
PURPOSE: We investigated the effect of ceramide on keratocyte apoptosis and pathway of ceramide-induced keratocyte apoptosis. METHODS: Cultured Newzealand White Rabbit keratocytes were exposed to various concentrations of ceramide type... -
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- Nafamostat for Prophylaxis against Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis Compared with Gabexate
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Chang JH, Lee IS, Kim HK, Cho YK, Park JM, Kim SW, Choi MG, Chung IS
- KMID: 2284064
- Gut Liver.
- 2009 Sep;3(3):205-210.
BACKGROUND/AIMS: The protease inhibitors, nafamostat and gabexate, have been used to prevent pancreatitis related to endoscopic retrograde cholangiopancreatography (ERCP). In vitro, nafamostat inhibits the pancreatic protease activities 10-100 times more... -
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- Use of Oral Hypoglycemic Agents in Type 2 Diabetic Patients with Hepatic Dysfunction
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Lee KY
- KMID: 2059849
- J Korean Diabetes.
- 2011 Dec;12(4):190-193.
- doi: 10.4093/jkd.2011.12.4.190
The prevalence of type 2 diabetes mellitus in the Korea has increased dramatically over the past decade. Clinicians can prescribe the following six currently available classes of oral hypoglycemic agents:... -
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- Treatment of chronic hepatitis C
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Jun DW
- KMID: 2342151
- J Korean Med Assoc.
- 2012 Nov;55(11):1113-1120.
In the past 10 years, the standard treatment for chronic hepatitis C has been pegylated interferon and ribavirin for 24 to 48 weeks, based on genotype. Until now, fixed schedule... -
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