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Maternal serum placental growth factor and pregnancy-associated plasma protein A measured in the first trimester as parameters of subsequent pre-eclampsia and small-for-gestational-age infants: A prospective observational study

Sung KU, Roh JA, Eoh KJ, Kim EH

OBJECTIVE: To examine the first-trimester maternal serum placental growth factor (PlGF) and pregnancy-associated plasma protein A (PAPP-A) levels in pregnancies associated with pre-eclampsia (PE) or small-for-gestational-age (SGA) infants, and determine...
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Screening for chromosomal abnormalities using combined test in the first trimester of pregnancy

Park SY, Jang IA, Lee MA, Kim YJ, Chun SH, Park MH

OBJECTIVE: This study was designed to review the screening performance of combined test at the Ewha Womans University Mokdong hospital. METHODS: All women admitted for routine antenatal care between January 1st...
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Diagnostic Performance of High-Sensitivity Troponin T, Myeloperoxidase, and Pregnancy-Associated Plasma Protein A Assays for Triage of Patients with Acute Myocardial Infarction

Khan DA, Sharif MS, Khan FA

BACKGROUND: Early diagnosis is the cornerstone of management of acute myocardial infarction (AMI). We aimed to compare the diagnostic accuracy of high-sensitivity troponin T (hs-cTnT) with myeloperoxidase (MPO) and pregnancy-associated...
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Clinical implications of nuchal translucency

Choi SJ

Fetal nuchal translucency (NT) is an echolucent space between the dorsal edge of soft tissue of the fetal neck and the linear echo of the skin observed in a midsagittal...
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Integrated Test for Screening in Down Syndrome as a Predictor of Adverse Pregnancy Outcomes

Park SW, Kang JH, Lee KJ, Jun HS, Kang MS, Huh JY, Cha DH

  • KMID: 2244894
  • J Genet Med.
  • 2009 Jun;6(1):74-80.
PURPOSE: To assess the value of first-trimester pregnancy-associated plasma protein-A (PAPP-A), nuchal translucency (NT) and second-trimester alpha-fetoprotein (AFP), human chorionic gonadotropin (hCG), unconjugated estriol (uE3), and inhibin-A in predicting pregnancy...
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A Research on the Actual Condition of Antenatal Screening Application in Obstetric Clinics in Korea and Suggestions for Preparation of Antenatal Screening Guideline

Chae YH, Seo K, Yoon DK, Oh JR, Lee MB, Lee KE

  • KMID: 2272759
  • Korean J Obstet Gynecol.
  • 2006 Jan;49(1):55-63.
OBJECTIVE: Many countries including U.S. have established their own Antenatal Screening Guideline suitable for their actual state to help Obstetricians detect pregnancy-related problems in clinical conditions. However, even investigations on...
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Recent Trends of Prenatal Screening for Down Syndrome

Kim MY

  • KMID: 2272753
  • Korean J Obstet Gynecol.
  • 2006 Jan;49(1):5-17.
Prenatal diagnosis of Down syndrome requires an invasive test in women considered to be at high risk after screening. At present, there are variable screening tests. For a 5% false-positive...
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Increased Activity of Insulin-like Growth Factor binding Protein-4 Protease in H-mole Patients

Seo WS, Byun DW, Mok JO, Yoon JS, Kim YJ, Park HK, Kim CH, Kim SJ, Suh KI, Yoo MH, Lee HH, Rah SK

  • KMID: 2200522
  • J Korean Soc Endocrinol.
  • 2004 Aug;19(4):346-357.
BACKGROUND: Hydatidiform mole (H-mole) is characterized by the neoplastic proliferation of trophoblasts. Only 1~10% of patients with partial H-mole will develop a trophoblastic tumor, but 18~29% of those with complete...
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The efficacy of nuchal translucency with free beta-hCG, PAPP-A as a screening test for detection of chromosomal anomaly in the first trimester of pregnancy

Kim SJ, Kim CM, Min BS, Sohn WS, Kang JB, Jang PR

  • KMID: 2262262
  • Korean J Obstet Gynecol.
  • 2001 Jun;44(6):1091-1096.
OBJECTIVES: The aim of this study is to determine the efficacy of nuchal translucency in combination with free beta-hCG, PAPP-A in the first trimester screening for chromosomal anomaly in general...
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The levels of insulin-like growth factor-binding proteins and their protease activity in serum and follicular fluid during the controlled ovarian hyperstimulation cycle

Kim JG, Suh CS, Kim SH, Choi YM, Moon SY, Lee YH, Lee JY

  • KMID: 2269998
  • Korean J Obstet Gynecol.
  • 2000 Mar;43(3):488-496.
OBJECTIVES: To evaluate changes in serum insulin-like growth factor binding protein(IGFBP)s profiles during the controlled hyperstimulation cycle and to compare IGFBPs profiles and their protease activity in follicular fluid(FF) from polycystic ovary...
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Evaluation of the Dual Test using PAPP-A and Free beta-hCG in First Trimester as a Prenatal Screening Test for Down Syndrome

Baek JY, Hong KS

  • KMID: 1931945
  • Korean J Clin Pathol.
  • 2000 Feb;20(1):18-23.
BACKGROUND: Dual test has been reported to be a useful first trimester screening test for Down syndrome and is comprised of measuring two serum parameters; pregnancy associated plasma protein A(PAPP-A)...
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