- Effect of Intracellular ATP on Zn2+ Blockade of KATP Channels in Pancreatic Beta Cells
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Song DK, Bae JH, Hong YS, Park WK
- KMID: 2298571
- Korean J Aerosp Environ Med.
- 1999 Mar;9(1):60-65.
In the therapeutic or the nutritional aspects, Zn2+ has been used as a supplement in a variety of drugs. Most of divalent or trivalent cations affect ion channels in the... -
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- Expression of ATP-sensitive potassium channel and sulfonylurea receptor in neonate and adult rat tissues
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Lee SY, Lee H, Lee MH, Ryu PD
- KMID: 1607083
- Korean J Physiol Pharmacol.
- 2001 Oct;5(5):433-441.
The ATP-sensitive potassium (KATP) channel is a member of inward rectifier potassium channel (Kir) that is inhibited by intracellular ATP and functions in close relation to sulfonylurea receptors (SUR). Although the molecular mechanism... -
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- A case of hypokalemic perodic paralysis induced by hyperinsulinemia
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Chang JH, Kim CS, Park JK, Park J, Cho MH, Ahn CW, Kim KR
- KMID: 1833291
- Korean J Med.
- 2005 Jun;68(6):692-696.
Hypokalemia periodic paralysis, a clinical syndrome characterised by systemic weakness and low serum potassium, is a rare but treatable cause of acute weakness. Attacks of flaccid paralysis can be associated... -
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- Intrinsic Gating in Inward Rectifier Potassium Channels (Kir2.1) with Low Polyamine Affinity Generated by Site Directed Mutagenesis
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So I, Ashmole I, Soh H, Park C, Spencer P, Leyland M, Stanfield
- KMID: 2071587
- Korean J Physiol Pharmacol.
- 2003 Jun;7(3):131-142.
We have studied mutant forms of Kir2.1 in which an aspartate residue (D172), important for gating by intracellular polyamines, is replaced by one of three basic residues (Arg, Lys or... -
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- Transient neonatal diabetes mellitus caused by a de novo ABCC8 gene mutation
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Kong JH, Kim JB
- KMID: 2284372
- Korean J Pediatr.
- 2011 Apr;54(4):179-182.
- doi: 10.3345/kjp.2011.54.4.179
Transient neonatal diabetes mellitus (TNDM) is a rare form of diabetes mellitus that presents within the first 6 months of life with remission in infancy or early childhood. TNDM is... -
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- The Substates with Mutants That Negatively Charged Aspartate in Position 172 Was Replaced with Positive Charge in Murine Inward Rectifier Potassium Channel (Murine Kir2.1)
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So I, Ashmole I, Stanfield
- KMID: 1517043
- Korean J Physiol Pharmacol.
- 2003 Oct;7(5):267-273.
We have investigated the effect on inducing substate (s) of positively charged residues replaced in position 172 of the second transmembrane domain in murine inward rectifier potassium channels, formed by... -
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- Multiple Residues in the P-Region and M2 of Murine Kir 2.1 Regulate Blockage by External Ba2+
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Lee YM, Thompson G, Ashmole I, Leyland M, So I, Stanfield
- KMID: 2285373
- Korean J Physiol Pharmacol.
- 2009 Feb;13(1):61-70.
- doi: 10.4196/kjpp.2009.13.1.61
We have examined the effects of certain mutations of the selectivity filter and of the membrane helix M2 on Ba2+ blockage of the inward rectifier potassium channel, Kir 2.1. We... -
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- Changes in Inward Rectifier K+ Channels in Hepatic Stellate Cells During Primary Culture
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Lee DH, Kong ID, Lee JW, Park KS
- KMID: 724263
- Yonsei Med J.
- 2008 Jun;49(3):459-471.
- doi: 10.3349/ymj.2008.49.3.459
PURPOSE: This study examined the expression and function of inward rectifier K+ channels in cultured rat hepatic stellate cells (HSC). MATERIALS AND METHODS: The expression of inward rectifier K+ channels... -
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- Long QT Syndrome: a Korean Single Center Study
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Lee YS, Kwon BS, Kim GB, Oh SI, Bae EJ, Park SS, Noh CI
- KMID: 1777681
- J Korean Med Sci.
- 2013 Oct;28(10):1454-1460.
- doi: 10.3346/jkms.2013.28.10.1454
The long QT syndrome (LQTS) is a rare hereditary disorder in which affected individuals have a possibility of ventricular tachyarrhythmia and sudden cardiac death. We investigated 62 LQTS (QTc >... -
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- Regulation of Ba2+-Induced Contraction of Murine Ureteral Smooth Muscle
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Kim YC, Lee MY, Kim WJ, Myung SC, Choi W, Kim CH, Xu WX, Kim SR, Lee SJ
- KMID: 2285344
- Korean J Physiol Pharmacol.
- 2007 Oct;11(5):207-213.
This study was designed to characterize ureteral smooth muscle motility and also to study the effect of forskolin (FSK) and isoproterenol (ISO) on smooth muscle contractility in murine ureter. High... -
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- Cloning of a pore-forming subunit of ATP-sensitive potassium channel from Clonorchis sinensis
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Hwang SY, Han HJ, Kim SH, Park SG, Seog DH, Kim NR, Han J, Chung JY, Kho WG
- KMID: 1080967
- Korean J Parasitol.
- 2003 Jun;41(2):129-133.
- doi: 10.3347/kjp.2003.41.2.129
A complete cDNA sequence encoding a pore-forming subunit (Kir6.2) of ATP-senstive potassium channel in the adult worm, Clonorchis sinensis, termed CsKir6.2, was isolated from an adult cDNA library. The cDNA... -
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- Sulfonylurea Therapy in Two Korean Patients with Insulin-treated Neonatal Diabetes due to Heterozygous Mutations of the KCNJ11 Gene Encoding Kir6.2
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Kim MS, Kim SY, Kim GH, Yoo HW, Lee DW, Lee DY
- KMID: 1127075
- J Korean Med Sci.
- 2007 Aug;22(4):616-620.
- doi: 10.3346/jkms.2007.22.4.616
Permanent neonatal diabetes (PND) is a rare form of diabetes characterized by insulin-requiring hyperglycemia diagnosed within the first three months of life. In most cases, the causes are not known.... -
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