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Evaluation of adjuvant effects of fucoidan for improving vaccine efficacy

Kim SY, Joo HG

Fucoidan is a sulfated polysaccharide derived from brown seaweed, including Fucus vesiculosus. This compound is known to have immunostimulatory effects on various types of immune cells including macrophages and dendritic...
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Corn silk induces nitric oxide synthase in murine macrophages

Kim KA, Choi SK, Choi HS

  • KMID: 1103321
  • Exp Mol Med.
  • 2004 Dec;36(6):545-550.
Corn silk has been purified as an anticoagulant previously and the active component is a polysaccharide with a molecular mass of 135 kDa. It activates murine macrophages to induce nitric...
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Fucoidan promotes osteoblast differentiation via JNK- and ERK-dependent BMP2-Smad 1/5/8 signaling in human mesenchymal stem cells

Kim BS, Kang HJ, Park JY, Lee J

Fucoidan has attracted attention as a potential drug because of its biological activities, which include osteogenesis. However, the molecular mechanisms involved in the osteogenic activity of fucoidan in human alveolar...
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Evaluation of Antibody Response to Polysaccharide Vaccine and Switched Memory B Cells in Pediatric Patients with Inflammatory Bowel Disease

Fallahi G, Aghamohammadi A, Khodadad A, Hashemi M, Mohammadinejad P, Asgarian-Omran H, Najafi M, Farhmand F, Motamed F, Soleimani , Soheili H, Parvaneh N, Darabi B, Nasiri Kalmarzi R, Pourhamdi , Abolhassani H, Mirminachi B, Rezaei N

  • KMID: 1774524
  • Gut Liver.
  • 2014 Jan;8(1):24-28.
BACKGROUND/AIMS: Inflammatory bowel disease (IBD) is a chronic disease of the gastrointestinal tract, whose etiologies are still unknown. This study was performed to evaluate the humoral immune response in terms...
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Radioprotective effects of fucoidan on bone marrow cells: improvement of the cell survival and immunoreactivity

Byon YY, Kim MH, Yoo ES, Hwang KK, Jee Y, Shin T, Joo HG

Fucoidan is a sulfated polysaccharide purified from brown algae including Fucus vesiculosus and has a variety of biological effects including mobilization of hematopoietic progenitor cells. Recently, we demonstrated that fucoidan...
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Inhibitory effect of red ginseng acidic polysaccharide from Korean red ginseng on phagocytic activity and intracellular replication of Brucella abortus in RAW 264.7 cells

Bernardo Reyes AW, Simborio H, Hop HT, Arayan LT, Min WG, Lee HJ, Rhee MH, Chang HH, Kim S

Korean red ginseng (KRG) has long been used in traditional Korean and Oriental medicine. However, the anti-bacterial mechanism and therapeutic efficiency of KGR for intracellular Brucella infection are still unclear....
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Radioprotective effects of an acidic polysaccharide of Panax ginseng on bone marrow cells

Kim HJ, Kim MH, Byon YY, Park JW, Jee Y, Joo HG

An acidic polysaccharide of Panax ginseng (APG), so called ginsan is known to have important immunomodulatory activities. It was recently reported that APG has radioprotective effects in mice but the...
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