- Treatment for Acute Stage Complex Regional Pain Syndrome Type II with Polydeoxyribonucleotide Injection
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Jang KS, Kim HS
- KMID: 2351725
- J Korean Neurosurg Soc.
- 2016 Sep;59(5):529-532.
- doi: 10.3340/jkns.2016.59.5.529
Complex regional pain syndrome (CRPS) type II is a syndrome that develops after nerve injury. Symptoms may be severe, and vary depending on the degree of sympathetic nerve involvement. As... -
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- The Effect of Polydeoxyribonucleotide on Chronic Non-healing Wound of an Amputee: A Case Report
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Shin J, Park G, Lee J, Bae H
- KMID: 2420058
- Ann Rehabil Med.
- 2018 Aug;42(4):630-633.
- doi: 10.5535/arm.2018.42.4.630
Polydeoxyribonucleotide (PDRN) is safe and effective in wound healing, cellular growth, synthesis of extracellular matrix protein, and inflammation reduction via activation of adenosine A2 receptors. We report a 28-year-old male... -
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- Effects of Polydeoxyribonucleotide in the Treatment of Pressure Ulcers
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Kim JY, Pak CS, Park JH, Jeong JH, Heo CY
- KMID: 2151417
- J Korean Med Sci.
- 2014 Nov;29(Suppl 3):S222-S227.
- doi: 10.3346/jkms.2014.29.S3.S222
This study aimed to examine the positive effects of polydeoxyribonucleotide (PDRN) on the wound-healing process in pressure ulcers. In this randomized controlled trial, the effects of PDRN were compared over... -
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- Efficacy and Safety of Intra-articular Injections of Hyaluronic Acid Combined With Polydeoxyribonucleotide in the Treatment of Knee Osteoarthritis
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Yoon S, Kang JJ, Kim J, Park S, Kim JM
- KMID: 2449003
- Ann Rehabil Med.
- 2019 Apr;43(2):204-214.
- doi: 10.5535/arm.2019.43.2.204
OBJECTIVE: To assess the clinical efficacy and safety of intra-articular injection of hyaluronic acid (HA) combined with polydeoxyribonucleotide (PDRN) in patients with knee osteoarthritis in comparison with that of HA... -
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- The Effects of Polydeoxyribonucleotide on the Survival of Random Pattern Skin Flaps in Rats
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Chung KI, Kim HK, Kim WS, Bae TH
- KMID: 2167918
- Arch Plast Surg.
- 2013 May;40(3):181-186.
- doi: 10.5999/aps.2013.40.3.181
BACKGROUND: Partial or complete necrosis of a skin flap is a common problem. Polydeoxyribonucleotide (PDRN) can be extracted from trout sperm and used as a tissue repair agent. The aim... -
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- Polydeoxyribonucleotides Improve Diabetic Wound Healing in Mouse Animal Model for Experimental Validation
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Kwon TR, Han SW, Kim JH, Lee BC, Kim JM, Hong JY, Kim BJ
- KMID: 2451477
- Ann Dermatol.
- 2019 Aug;31(4):403-413.
- doi: 10.5021/ad.2019.31.4.403
BACKGROUND: Wound healing mechanisms is believed to have effects similar to wound healing disorders in diabetic patients, including abnormal inflammatory cells, angiogenesis disorders, and reduced collagen synthesis. Therefore, reestablishment of... -
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- Protective Effect of Defibrotide on Splanchnic Injury following Ischemia and Reperfusion in Rats
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Choi SR, Jeong JH, Song JH, Shin YK
- KMID: 2071625
- Korean J Physiol Pharmacol.
- 2006 Apr;10(2):85-94.
A splanchic artery occlusion for 90 min followed by reperfusion of the mesenteric circulation resulted in a severe form of circulatory shock, characterized by endothelial dysfunction, severe hypotension, marked intestinal... -
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- Polydeoxyribonucleotide Improves Peripheral Tissue Oxygenation and Accelerates Angiogenesis in Diabetic Foot Ulcers
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Kim S, Kim J, Choi J, Jeong W, Kwon S
- KMID: 2403948
- Arch Plast Surg.
- 2017 Nov;44(6):482-489.
- doi: 10.5999/aps.2017.00801
BACKGROUND: Polydeoxyribonucleotide (PDRN) is known to have anti-inflammatory and angiogenic effects and to accelerate wound healing. The aim of this study was to investigate whether PDRN could improve peripheral tissue... -
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- 6-Thioguanine-Induced Hepatic Sinusoidal Obstruction Syndrome in a Leukemic Child with TPMT Heterozygote
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Kwon YJ, Yoon JH, Park JA, Bang JS, Park BK, Choi JI, Kong SY, Park HJ
- KMID: 2049280
- Clin Pediatr Hematol Oncol.
- 2012 Oct;19(2):109-113.
Hepatic sinusoidal obstruction syndrome (hSOS) can be developed as a common complication after hematopoietic stem cell transplantation (HSCT), and rarely after 6-thioguanine-based chemotherapy without HSCT. A four-year-old boy with heterozygotic... -
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- Effect of Polydeoxyribonucleotide on Lipopolysaccharide and Sevoflurane-Induced Postoperative Cognitive dysfunction in Human Neuronal SH-SY5Y Cells
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Jeong H, Chung JY, Ko IG, Kim SH, Jin JJ, Hwang L, Moon EJ, Lee BJ, Yi JW
- KMID: 2467317
- Int Neurourol J.
- 2019 Nov;23(Suppl 2):S93-S101.
- doi: 10.5213/inj.1938218.109
PURPOSE: Postoperative cognitive dysfunction (POCD) is a complication of surgery characterized by acute cognitive dysfunction, memory impairment, and loss of attention. The effect of polydeoxyribonucleotide (PDRN) on the POCD environment... -
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