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Indirect Effects of Pneumococcal Conjugate Vaccines in National Immunization Programs for Children on Adult Pneumococcal Disease

Kim YK, LaFon D, Nahm MH

The pneumococcal conjugate vaccine (PCV) was developed to overcome the limitations of the pneumococcal polysaccharide vaccine, which produces poor immunogenicity in infants younger than 2 years. As many countries have...
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Vaccination for preventing pneumococcal infection

Cha SH

No abstract available.
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Pneumococcal vaccine

Song JY, Cheong HJ

Streptococcus pneumoniae (pneumococcus) is an important pathogen with high morbidity and mortality worldwide. Pneumococcal vaccine is an important measure to reduce the pneumococcal disease burden. Currently, two pneumococcal vaccines are...
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The prevention of pneumococcal infections

Chang MS, Woo JH

No abstract available.
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Role of Coagulation Factor 2 Receptor during Respiratory Pneumococcal Infections

Shin SG, Bong Y, Lim JH

Coagulation factor 2 receptor (F2R), also well-known as a protease-activated receptor 1 (PAR1), is the first known thrombin receptor and plays a critical role in transmitting thrombin-mediated activation of intracellular...
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The Changing Epidemiology of Childhood Pneumococcal Disease in Korea

Choe YJ, Choi EH, Lee HJ

The wide use of antimicrobial agents and 7-valent pneumococcal conjugate vaccine (PCV7) has led to major changes in the epidemiology of childhood pneumococcal diseases. In Korea, data on the population-based...
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Role of the transforming growth factor (TGF)-β1 and TGF-β1 signaling pathway on the pathophysiology of respiratory pneumococcal infections

Andrade MJ, Lim JH

Streptococcus pneumoniae, pneumococcus, is the most common cause of community-acquired pneumonia (CAP). CAP is an important infectious disease with high morbidity and mortality, and it is still one of the...
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Functional Immunity to Cross-Reactive Serotype 6A Induced by Serotype 6B in Pneumococcal Polysaccharide Vaccine

Kim KH

  • KMID: 2278624
  • Korean J Pediatr.
  • 2005 May;48(5):506-511.
PURPOSE: Streptococcus pneumoniae serotype 6B and 6A are important pathogens in pneumococcal infections. It is commonly assumed that the 6B vaccines elicit antibodies cross-reacting with the 6A serotype and the...
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Vaccination for Diabetic Patients: An Update

Yeom JS

As Korean populations are getting older and the number of adults with diabetes is continually increasing, importance of prevention of infectious diseases through vaccination has increased. With recent introduction of...
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Use of vaccine in the era of antimicrobial resistance: need of effective pneumococcal vaccines

Sohn YM

Streptococcus pneumoniae is an important pathogen causing invasive infections particularly in children. Penicillin-nonsusceptible pneumococci are very prevalent in Korea and a difficult problem in antimicrobial treatment. Immunization with effective vaccines...
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Pneumococcal Vaccination Rate among Elderly in South Korea

Lim J, Eom CS, Kim S, Ke S, Cho B

  • KMID: 2339076
  • J Korean Geriatr Soc.
  • 2010 Mar;14(1):18-24.
BACKGROUND: Pneumococcal vaccination among elderly is important for prevention of pneumonia and invasive pneumococcal disease (IPD). There are few studies of pneumococcal vaccination among elderly in South Korea. The aim...
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A Case of Hemolytic Uremic Syndrome Induced by Pneumococcal Infection

Sim YH, Lim IS, Choi ES

  • KMID: 2322075
  • J Korean Soc Pediatr Nephrol.
  • 2002 Oct;6(2):237-242.
Hemolytic Uremic Syndrome (HUS) is the most common cause of acute renal failure in children and is comprised of the combination of hemolytic anemia, thrombocytopenia, and acute renal failure. Atypical...
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Changing Patterns of Antibiotic-resistant Rates and Clinical Features in Pneumococcal Infections

Jang GC, Shin KM, Yong DE, Lee KW, Kim DS

PURPOSE: Streptococcus pneumoniae remains a leading cause of meningitis, sepsis, pneumonia, and otitis media in children worldwide. Emergence of drug-resistant organism has substantially complicated the therapy of these infections. This...
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Interleukin-1beta Participates in the Development of Pneumococcal Acute Lung Injury and Death by Promoting Alveolar Microvascular Leakage

Bong Y, Shin SG, Koh SH, Lim JH

Streptococcus pneumoniae (S. pneumoniae, also known as pneumococcus) infections are major causes of death worldwide. Despite the development and use of effective antibiotics, high, early mortality due to pneumococcal infections...
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A Case on Streptococcal Pneumonia Associated with Leptomeningitis, Osteomyelitis and Epidural Abscess in a Patient with AIDS

Jeon JW, Yoon HJ, Kim JS, Ryu IH, Choi JW, Kim MG, Na YM, Yun HJ

Patients with acquired immunodeficiency syndrome (AIDS) are at higher risks of bacterial pneumonia than the general population, and the pathogen is the most commonly involved Streptococcus pneumoniae. We hereby report...
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Clinical Implications of Pneumococcal Serotypes: Invasive Disease Potential, Clinical Presentations, and Antibiotic Resistance

Song JY, Nahm MH, Moseley MA

Streptococcus pneumoniae can asymptomatically colonize the nasopharynx and cause a diverse range of illnesses. This clinical spectrum from colonization to invasive pneumococcal disease (IPD) appears to depend on the pneumococcal...
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Evaluation of antibody responses to pneumococcal vaccines with ELISA and opsonophagocytic assay

Kim KH, Seoh JY

Antibodies to a capsular polysaccharide (PS) provide protection against Streptococcus pneumoniae which express the homologous capsular serotype, and pneumococcal vaccines are designed to induce antibodies in the capsular PS. Levels...
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The in vivo and in vitro Roles of Epithelial Pattern Recognition Receptors in Pneumococcal Infections

Shin SG, Koh SH, Lim JH

Streptococcus pneumoniae, also called pneumococcus, is a major cause of infectious disease in human. Pneumococcus resides in the nasopharynx as an upper respiratory commensal, and most of pneumococcal colonizations are...
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A study of serotyping of Streptococcus pneumoniae by multibead assay

Cho KY, Lee JA, Cho SE, Kim NH, Lee JA, Hong KS, Lee HJ, Kim KH

PURPOSE: Streptococcus pneumoniae is a major etiologic agent for pneumonia, meningitis, otitis media, and sepsis among young children. Multi-drug resistant strains have raised great concern worldwide, thus the importance of...
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A case of overwhelming postsplenectomy infection with purpura fulminans by Streptococcus pneumoniae

Yoo JY, Song HG, Lee JH, Kim KS, Lee SS, Kim HJ, Chung DR

  • KMID: 2305983
  • Korean J Med.
  • 2006 Jun;70(6):725-728.
The most serious problem after splenectomy is the increased risk of life-threatening infections caused by encapsulated bacteria such as Streptococcus pneumoniae, Haemophilus influenzae, and Neisseria meningitidis. Purpura fulminans, which is...
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