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The Treatment Experience of Lymphatic Malformations in Pediatric Patients

Park JH, Nam SH

PURPOSE: The management of lymphatic malformation (LM) in pediatric patients is challenging. Complete excision of LM is difficult to achieve in some cases. We reviewed our experience how to manage...
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Infusion Sclerotherapy of Microcystic Lymphatic Malformation: Clinico-Radiological Mid-Term Results

Lee J, Lee SJ, Chung HY, Huh S, Kim HK

PURPOSE: A new sclerotherapy technique by slow mechanical infusion of sclerosant was validated for treatment of microcystic lymphatic malformation (mLM). MATERIALS AND METHODS: Seventeen consecutive patients with mLM in extremities, cervicofacial...
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Surgical Treatment of Difficult Cervicofacial Lymphangioma in Children

Hwang D, Lee S, Lim SY, Lee SK, Seo JM

PURPOSE: Cervical lymphangiomas are rare lymphovascular malformations arising in the neck, which form huge fluid-containing cysts. Treatment of the malformation consists of surgery and sclerotherapy. However, the optimal approach is...
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Ultrasound-guided sclerotherapy for benign non-thyroid cystic mass in the neck

Kim JH

  • KMID: 2319362
  • Ultrasonography.
  • 2014 Apr;33(2):83-90.
Surgical excision has traditionally been the treatment of choice for benign non-thyroid cystic neck masses, including lymphatic malformation, ranula, branchial cleft cyst, thyroglossal duct cyst, and parathyroid cyst. However, there...
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Sclerotherapy of cystic lymphangioma

Won JH

Cystic lymphangioma is a congenital lymphatic malformation that occurs most commonly in the head and neck. Most lymphangiomas are asymptomatic, but progressive enlargement may cause feeding difficulty, airway, and cosmetic...
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Intrauterine therapy for macrocystic congenital cystic adenomatoid malformation of the lung

Min JY, Won HS, Lee MY, Suk HJ, Shim JY, Lee PR, Kim A

  • KMID: 2313992
  • Obstet Gynecol Sci.
  • 2014 Mar;57(2):102-108.
OBJECTIVE: To report on our experiences with thoracoamniotic shunting and/or the injection of a sclerosing agent (OK-432) to treat fetuses diagnosed with macrocystic congenital cystic adenomatoid malformation (CCAM) of the...
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Lymphatic Malformations of the Orbit

Wiegand S, Eivazi B, Bloch LM, Zimmermann AP, Sesterhenn AM, Schulze S, Werner JA

  • KMID: 2278518
  • Clin Exp Otorhinolaryngol.
  • 2013 Mar;6(1):30-35.
OBJECTIVES: Lymphatic malformations of the orbit are rare lesions that constitute approximately 1% to 8% of all orbital masses. They are difficult to treat since they do not remain within...
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Successful pleurodesis with OK-432 in preterm infants with persistent pleural effusion

Kim JE, Lee C, Park KI, Park MS, Namgung R, Park IK

OK-432 (picibanil) is an inactivated preparation of Streptococcus pyogenes that causes pleurodesis by inducing a strong inflammatory response. Intrapleural instillation of OK-432 has recently been used to successfully treat neonatal...
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A Case of Pseudo-Meigs' Syndrome Associated with Ovarian Metastases from Breast Cancer

Naito K, Oura S, Yasuoka H, Okamura Y

A 54-year-old woman with long-lasting pleural effusion developed abdominal distention due to ascites from bilateral ovarian tumors. The patient had undergone breast-conserving surgery and axillary lymph node dissection for left...
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The Utility of Sono-Guided Sclerotherapy for Benign Thyroid Cyst: Prospective Study

Oh SK, Lee JY, Lee DH, Moon IH, Kwon KN, Park KN, Lee SW

BACKGROUND AND OBJECTIVES: Ultrasonography (USG)-guided sclerotherapy using a sclerotherapic agent such as ethanol, OK-432, recently has gained popularity as a treatment for nonfunctioning benign thyroid nodules. The study evaluates the...
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Cesarean delivery with postnatal high-frequency ventilation immediately after thoracocentesis for a fetus with intractable congenital chylothorax

Kim GJ, Lee ES

We experienced a case of fetus with congenital chylothorax who treated with thoracocentesis immediately followed by cesarean delivery with high frequency ventilation therapy after treatment failure by serial thoracocentesis and...
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Efficacy of Dendritic Cells Matured Early with OK-432 (Picibanil(R)), Prostaglandin E2, and Interferon-alpha as a Vaccine for a Hormone Refractory Prostate Cancer Cell Line

Yoo C, Do HA, Jeong IG, Park H, Hwang JJ, Hong JH, Cho JS, Choo MS, Ahn H, Kim CS

Dendritic cells (DCs) are potent antigen-presenting cells. OK432 (Picibanil(R)) was introduced as a potent stimulator of DC maturation in combination with prostaglandin-E2 and interferon-alpha. We compared the efficacy of a...
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Successful Treatment of Steatocystoma Multiplex with OK-432 Sclerotherapy

Park SY, Nam HM, Park K, Park SD

  • KMID: 2247700
  • Korean J Dermatol.
  • 2010 Jun;48(6):529-532.
Steatocystoma multiplex is a hamartomatous malformation of the pilosebaceous junction and this manifests as multiple, asymptomatic, yellowish or skin-colored cystic papules and nodules located most commonly on the upper anterior...
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Infantile Fibrosarcoma in Neonate

Nam SH, Cho MJ, Kim DY, Kim SC, Kim IK

Infantile fibrosarcoma is a rare malignant soft tissue tumor occurring especially in newborn and young children under 2 years. We experienced three cases of infantile fibrosarcoma presenting in the neonatal...
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Successful antenatal treatment of early fetal chylothorax with OK-432 pleurodesis

Yim GW, Kwon JY, Park YW, Kim YH

  • KMID: 2273744
  • Korean J Obstet Gynecol.
  • 2009 Jul;52(7):752-758.
Fetal chylothorax is a rare congenital manifestation that shows variable clinical outcome ranging from complete spontaneous resolution to progression into hydrops or lung hypoplasia. There is no consensus in the...
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Evaluation of Intralesional Injection Therapy for Pediatric Lymphangiomas Classified with MRI

Kim IK, Moon SB, Baek SH, Seo JM, Lee SK

  • KMID: 2059031
  • J Korean Assoc Pediatr Surg.
  • 2009 Dec;15(2):113-120.
Pediatric lymphangioma can occur at any site. However the neck is the most common site. There are two treatment modalities (surgical excision and intralesional injection) for lymphangiomas. But, the treatment...
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Picibanil Sclerotherapy for Intractable Chylous Leakage After Neck Dissection

Chang H, Ahn Y, Sung MW, Kim KH

  • KMID: 2276939
  • Korean J Otorhinolaryngol-Head Neck Surg.
  • 2008 Sep;51(9):846-849.
undergo radical neck dissection. Subsequent chyle leakage can cause complications such as skin flap necrosis, orocutaneous fistula, electrolyte imbalance and protein loss. Chyle leakage is managed conservatively with total parenteral...
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A Case of Lymphangioma Treated by OK-432 (Picibanil(R)) Sclerotherapy

Kim BS, Won TH, Seo PS, Park SD

  • KMID: 2248078
  • Korean J Dermatol.
  • 2008 Oct;46(10):1398-1401.
Lymphangioma is an uncommon, benign hyperproliferation of the lymphatic vessels, and this consists of dilated lymphatic channels lined by a normal, single layer of endothelial cells. Various methods have been...
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Percutaneous Treatment of Renal Cysts with OK-432 Sclerosis

Choi YD, Cho SY, Cho KS, Lee DH, Lee SH

PURPOSE: The aim of this study was to demonstrate OK- 432 sclerotherapy efficacy for treatment of simple renal cysts. MATERIALS AND METHODS: Twenty patients with 25 symptomatic or large simple...
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Treatment of lymphangioma by surgical excision and sclerotherapy with OK-432: A case report

Cho JY, Cha D, Baek SH, Lee JD

  • KMID: 1567721
  • J Korean Assoc Oral Maxillofac Surg.
  • 2006 Jun;32(3):267-271.
32.
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