J Korean Ophthalmol Soc.  2006 Mar;47(3):489-493.

A Case Report: Treatment of Orbital Lymphangioma with Intralesional OK-432 Injection

• Choi JB
• Yoon JS
• Choi JY
• Lee SY

Abstract

PURPOSE: To report the first domestic case of orbital lymphangioma treated with intralesional OK-432 injection.
METHODS
Initial treatment with systemic corticosteroid had failed. After aspirating the blood, we injected OK-432 (0.05 mg) into the cystic space of the orbital lymphangioma.
RESULTS
Although there were minor complications, such as fever and mild tenderness, the patient had an uneventful recovery. After 6 weeks, her visual axis was restored.
CONCLUSIONS
We successfully treated this infant patient with an intralesional OK-432 injection. Based on this success, we suggest that treatment of orbital lymphangioma which is refractory to conservative treatment and difficult to resect, may include an intralesional OK-432 injection.

Keyword

OK-432; Orbital lymphangioma

MeSH Terms

Axis, Cervical Vertebra
Fever
Humans
Infant
Lymphangioma*
Orbit*
Picibanil*
Picibanil