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The Rate of Conversion from Immune-tolerant Phase to Early Immune-clearance Phase in Children with Chronic Hepatitis B Virus Infection

Hong SJ, Park HJ, Chu MA, Choi BS, Choe BH

  • KMID: 2315464
  • Pediatr Gastroenterol Hepatol Nutr.
  • 2014 Mar;17(1):41-46.
PURPOSE: The spontaneous seroconversion rate of hepatitis B e antigen (HBeAg)-positive chronic hepatitis B (CHB) virus infection in children is lower than that in adults. However, few studies have investigated...
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Effect of bFGF on the MCF-7 Cell Cycle with CD44+/CD24-: Promoting the G0/G1-->G2/S Transition

Yang ZL, Cheng K, Han ZD

PURPOSE: Few cells with stem cell characteristics possess capabilities of self-renewal and differentiation, which leads to high tumorigenesis and resistance to standard chemotherapeutic agents. These cells are mostly quiescent, and...
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Rheological characterization of thermoplasticized injectable gutta percha and resilon

Chang J, Baek SH, Lee IB

OBJECTIVES: The purpose of this study was to observe the change in the viscoelastic properties of thermoplasticized injectable root canal filling materials as a function of temperature and to compare...
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Molecular Biological Responses of TCDD Transformed Human Keratinocytes Induced by UVB Irradiation

Ham HJ, Kim DK, Han KH

  • KMID: 1559026
  • Korean J Anat.
  • 2001 Aug;34(4):335-344.
The expression of nm23-H1, nm23-H2, p53, c-myc, cyclin D1, and k-ras genes were investigated in TCDD transformed human keratinocyte RHEK1 cells by exposure to UVB 200 J/m2. For 3 days...
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The effects of gamma-radiation on cyclin-dependent kinases and their inhibitors in cultured vascular smooth muscle cells

Zo JH

BACKGROUND: In spite of the clinical introduction of brachytherapy to reduce restenosis, the biologic responses of vascular smooth muscle cells(VSMCs) to radiation have not been well studied. We investigated the...
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Dysregulation of Cell Cycle Regulating Proteins in Peripheral Lymphocytes from the Patients with Alzheimer's Disease

Chung SH, Kwon YA, Kim H, Shin JY, Kim DK

  • KMID: 2286986
  • Korean J Psychopharmacol.
  • 2004 Dec;15(4):474-479.
OBJECTIVE: Extensive neuronal death occurring in the Alzheimer's disease (AD) may be related with the apoptosis. Recent studies have suggested that regulatory failure of cell cycle appeared to be very...
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Thermoresponsive and Biodegradable Amphiphilic Block Copolymers with Pendant Functional Groups

Lee BK, Noh JH, Park JH, Park SH, Kim JH, Oh SH, Kim MS

BACKGROUND: To develop the biodegradability and thermoresponsive hydrogel, in this work we designed a pendant-functionalized, thermoresponsive, amphiphilic block copolymer. METHODS: Methoxy poly(ethylene glycol) (MPEG)-b-[poly(ε-caprolactone)-ran-poly(ε-caprolactone-3-one)-ran-polylactic acid] (MCL) and (MPEG-b-[PCL-ran-POD-ran-PLA]) [MCL-(CO)] block copolymers...
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In Situ Cross-Linkable Hydrogels as a Dynamic Matrix for Tissue Regenerative Medicine

Park KM, Park KD

BACKGROUND: Polymeric hydrogels are extensively used as promising biomaterials in a broad range of biomedical applications, including tissue engineering, regenerative medicine, and drug delivery. These materials have advantages such as...
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Anti-obesity effect of EGCG and glucosamine-6-phosphate through decreased expression of genes related to adipogenesis and cell cycle arrest in 3T3-L1 adipocytes

Kim KB, Jang SH

  • KMID: 2327454
  • J Nutr Health.
  • 2014 Feb;47(1):1-11.
PURPOSE: Several studies have proven that EGCG, the primary green tea catechin, and glucosamine-6-phosphate (PGlc) reduce triglyceride contents in 3T3-L1 adipocytes. The objective of this study is to evaluate the...
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Surface characteristics of thermally treated titanium surfaces

Lee YJ, Cui DZ, Jeon HR, Chung HJ, Park YJ, Kim OS, Kim YJ

PURPOSE: The characteristics of oxidized titanium (Ti) surfaces varied according to treatment conditions such as duration time and temperature. Thermal oxidation can change Ti surface characteristics, which affect many cellular...
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Human Papillomavirus Infection and Expression of Cyclin D1 in the Uterine Cervical Neoplasia

Kim MK, Kim HB, Lee SK, Sunwoo JG, Bae DH, Kim CJ

  • KMID: 2143478
  • Korean J Gynecol Oncol Colposc.
  • 2002 Mar;13(1):28-37.
About 80 subtypes of human papilloma viruses(HPVs) were known, and they were divided into two groups as 'high-risk HPVs' and 'low-risk HPVs' according to their oncogenic potentialities. Even though the...
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Phase Variation of Biofilm Formation in Staphylococcus aureus by IS 256 Insertion and Its Impact on the Capacity Adhering to Polyurethane Surface

Kiem S, Oh WS, Peck KR, Lee NY, Lee JY, Song JH, Hwang ES, Kim EC, Cha CY, Choe KW

While ica gene of Staphylococcus epidermidis is known to undergo phase variation by insertion of IS256, the phenomenon in Staphylococcus aureus has not been evaluated. Six biofilm-positive strains were tested...
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Effect of Mefloquine, a Gap Junction Blocker, on Circadian Period2 Gene Oscillation in the Mouse Suprachiasmatic Nucleus Ex Vivo

Koo J, Choe HK, Kim HD, Chun SK, Son GH, Kim K

BACKGROUND: In mammals, the master circadian pacemaker is localized in an area of the ventral hypothalamus known as the suprachiasmatic nucleus (SCN). Previous studies have shown that pacemaker neurons in...
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The Expressions of E2F1 and p53 in Gastrointestinal Stromal Tumors and Their Prognostic Significance

Kwon MJ, Nam ES, Cho SJ, Park HR, Shin HS, Lee JS, Park CH, Shin WG

  • KMID: 1979338
  • Korean J Pathol.
  • 2009 Jun;43(3):212-220.
BACKGROUND: E2F1 plays a critical role in the G1-to-S phase transition by inducing various genes that encode S phase-activating proteins and that modulate such diverse cellular functions as DNA synthesis,...
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Expression of cyclin E in gestational trophoblastic disease

Yi JW, Kim YT, Kim JW, Kim SH, Kim DK

  • KMID: 2143479
  • Korean J Gynecol Oncol Colposc.
  • 2002 Mar;13(1):38-48.
Gestational trophoblastic disease represents a spectrum of lesions characterized by an abnormal proliferation of trophoblast, including partial mole, complete mole, invasive mole, choriocarcinoma, and placental site trophoblastic tumor, which have...
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Poloxamer 407 Hydrogels for Intravesical Instillation to Mouse Bladder: Gel-Forming Capacity and Retention Performance

Kim SH, Kim SR, Yoon HY, Chang IH, Whang YM, Cho MJ, Kim MJ, Kim SY, Lee SJ, Choi YW

PURPOSE: Poloxamer 407 (P407) thermo-sensitive hydrogel formulations were developed to enhance the retention time in the urinary bladder after intravesical instillation. MATERIALS AND METHODS: P407 hydrogels (P407Gels) containing 0.2 w/w% fluorescein...
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Detection of alpha-thalassemia-1 Southeast Asian and Thai Type Deletions and beta-thalassemia 3.5-kb Deletion by Single-tube Multiplex Real-time PCR with SYBR Green1 and High-resolution Melting Analysis

Pornprasert S, Wiengkum T, Srithep S, Chainoi I, Singboottra P, Wongwiwatthananukit S

BACKGROUND: Prevention and control of thalassemia requires simple, rapid, and accurate screening tests for carrier couples who are at risk of conceiving fetuses with severe thalassemia. METHODS: Single-tube multiplex real-time PCR...
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Effect of Retrovirus and p53 Tumor Suppressor Gene in Gene Therapy of Cancer Cells

Suh SI, Suh MH, Baek WK, Cho JW

  • KMID: 2099290
  • J Korean Soc Microbiol.
  • 1998 Apr;33(2):227-235.
Cancer is considered to occur through abnormal growth and differentiation processes, in which oncogenes and tumor suppressor genes are deeply related. Cellular responses to DNA-damaging agents are believed to be...
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