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Putative Association of ITGB1 Haplotype with the Clearance of HBV Infection

Park TJ, Chun JY, Bae JS, Kim JY, Lee JS, Pasaje CF, Park BL, Cheong HS, Lee HS, Kim YJ, Shin HD

  • KMID: 2166472
  • Genomics Inform.
  • 2010 Mar;8(1):9-18.
Integrins are transmembrane receptor proteins that mediate cell-cell adhesion and cell-extracellular matrix (ECM) adhesion. The deregulation of cell-ECM adhesion and the abnormal expression of beta1 (beta1) integrins (ITGB1s) are involved...
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WDR46 is a Genetic Risk Factor for Aspirin-Exacerbated Respiratory Disease in a Korean Population

Pasaje CF, Bae JS, Park BL, Cheong HS, Kim JH, Uh ST, Park CS, Shin HD

PURPOSE: The human WD repeat-containing protein 46 (WDR46; also known as C6orf11), located at the disease-relevant centromere side of the class II major histocompatibility complex region, is hypothesized to be...
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Polymorphisms of ATF6B Are Potentially Associated With FEV1 Decline by Aspirin Provocation in Asthmatics

Park TJ, Kim JH, Pasaje CF, Park BL, Bae JS, Uh ST, Kim YH, Kim MK, Choi IS, Choi BW, Shin HR, Park JS, Koh I, Park CS, Shin HD

PURPOSE: Endoplasmic reticulum (ER) stress has recently been observed to activate NF-kappaB and induce inflammatory responses such as asthma. Activating transcription factor 6beta (ATF6B) is known to regulate ATFalpha-mediated ER...
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Association Analysis Between FILIP1 Polymorphisms and Aspirin Hypersensitivity in Korean Asthmatics

Kim JY, Kim JH, Park BL, Pasaje CF, Bae JS, Park JS, Jang AS, Uh ST, Kim YH, Kim MK, Choi IS, Cho SH, Choi BW, Park CS, Shin HD

PURPOSE: Aspirin exacerbated respiratory disease (AERD) results in a severe asthma attack after aspirin ingestion in asthmatics. The filamin A interacting protein 1 (FILIP1) may play a crucial role in...
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Potential Association of DCBLD2 Polymorphisms with Fall Rates of FEV1 by Aspirin Provocation in Korean Asthmatics

Park TJ, Kim JH, Park BL, Cheong HS, Bae JS, Pasaje CF, Park JS, Uh ST, Kim MK, Choi IS, Park CS, Shin HD

Aspirin exacerbated respiratory disease (AERD) is a clinical syndrome characterized by chronic rhinosinusitis with nasal polyposis and aspirin hypersensitivity. The aspirin-induced bronchospasm is mediated by mast cell and eosinophilic inflammation....
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