- No evidence of association between interleukin-13 gene polymorphism in aspirin intolerant chronic urticaria
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Palikhe NS, Kim SH, Choi GS, Ye YM, Park HS
- KMID: 2133797
- Allergy Asthma Immunol Res.
- 2009 Oct;1(1):36-40.
- doi: 10.4168/aair.2009.1.1.36
Aspirin-intolerant chronic urticaria (AICU) is a common condition among the chronic urticaria population, but the genetic mechanism is not yet understood. In this study, the genotypes and haplotypes of three... -
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- Polymorphisms of Aspirin-Metabolizing Enzymes CYP2C9, NAT2 and UGT1A6 in Aspirin-Intolerant Urticaria
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Palikhe NS, Kim SH, Nam YH, Ye YM, Park HS
- KMID: 2167079
- Allergy Asthma Immunol Res.
- 2011 Oct;3(4):273-276.
- doi: 10.4168/aair.2011.3.4.273
Acetyl salicylic acid (ASA) is metabolized by UDP-glucuronosyltransferase 1A6 (UGT1A6), cytochrome P4502C9 (CYP2C9), and N-acetyl transferase 2 (NAT2). Variations in the activities of these enzymes may modulate adverse ASA-related symptoms... -
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- Update on Recent Advances in the Management of Aspirin Exacerbated Respiratory Disease
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Palikhe NS, Kim JH, Park HS
- KMID: 1777085
- Yonsei Med J.
- 2009 Dec;50(6):744-750.
- doi: 10.3349/ymj.2009.50.6.744
Aspirin intolerant asthma (AIA) is frequently characterized as an aspirin (ASA)-exacerbated respiratory disease (AERD). It is a clinical syndrome associated with chronic severe inflammation in the upper and lower airways... -
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- Role of Toll-like Receptor 3 Variants in Aspirin-Exacerbated Respiratory Disease
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Palikhe NS, Kim SH, Kim JH, Losol P, Ye YM, Park HS
- KMID: 2130364
- Allergy Asthma Immunol Res.
- 2011 Apr;3(2):123-127.
- doi: 10.4168/aair.2011.3.2.123
PURPOSE: Although the mechanism of virus-induced, aspirin-exacerbated respiratory disease (AERD) is not known fully, direct activation of viral components through Toll-like receptor 3 (TLR3) has been suggested. TLR3 recognizes double-stranded... -
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- IL-13 Gene Polymorphisms are Associated With Rhinosinusitis and Eosinophilic Inflammation in Aspirin Intolerant Asthma
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Palikhe NS, Kim SH, Cho BY, Choi GS, Kim JH, Ye YM, Park HS
- KMID: 2260600
- Allergy Asthma Immunol Res.
- 2010 Apr;2(2):134-140.
- doi: 10.4168/aair.2010.2.2.134
PURPOSE: Aspirin-intolerant asthma (AIA) is characterized by moderate to severe asthma that is aggravated by aspirin or other non-steroidal anti-inflammatory drugs. Affected patients frequently have chronic rhinosinusitis and nasal polyposis... -
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- Biomarkers Predicting Isocyanate-Induced Asthma
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Palikhe NS, Kim JH, Park HS
- KMID: 2260373
- Allergy Asthma Immunol Res.
- 2011 Jan;3(1):21-26.
- doi: 10.4168/aair.2011.3.1.21
Three diisocyanates can cause occupational asthma (OA): toluene diisocyanate (TDI), 4,4 diphenylmethane diisocyanate (MDI), and 1,6-hexamethylene diisocyanate (HDI). We analyzed potential biomarkers of isocyanate-induced OA, based on investigated immunologic, genetic,... -
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