- Hyberthermia in the Rat from Handling and Injection Stress
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Pae YS
- KMID: 1967583
- Ewha Med J.
- 1984 Dec;7(4):267-269.
- doi: 10.12771/emj.1984.7.4.267
Experimental handling and colonic temperature measurement have been shown to cause stress and induce a long lasting rise in colonic temperature in the rat. Injection is also a type of... -
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- Turning Behavior and Substantia Nigra Structure After Unilateral Lesion and of the Rat Neostriatum
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Pae YS
- KMID: 2170815
- Ewha Med J.
- 1988 Dec;11(4):225-235.
- doi: 10.12771/emj.1988.11.4.225
After unilateral lesion of the rat neostriatum, we have been studied the relation between the behavioral chages of the rat and structural chages of the substantia nigra. We could find... -
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- Blockade by Naloxone and Naltrexone of the TRH-induced Stimulation of Colonic Transit in the Rabbit
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Pae YS
- KMID: 1967572
- Ewha Med J.
- 1984 Dec;7(4):187-190.
- doi: 10.12771/emj.1984.7.4.187
Thyrotropin releasing hormore(TRH) administered intracerebroventricularly (i.c.v) in microgram quantities to anesthetized rabbits, produces marked stimulation of colonic motility, transit and fluid accumulation. These effects depend on an intact vagal system.... -
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- Effect of Naloxone on the Mixed- Function Oxidation and Lipid Peroxidation in Rat Liver Microsomes
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Hong YS, Sung NE, Pae YS
- KMID: 1965692
- Ewha Med J.
- 1986 Sep;9(3):153-161.
- doi: 10.12771/emj.1986.9.3.153
The effects of Naloxone, narcotic antagonist, pretreated with normal saline, salicylate and hydrocortisone produced by with hypovolemic shock on the rates of cytochrome components, mixed function oxidation enzyme reactions and... -
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- Studies on the Hepatic Microsomal Mixed Function Oxidase System with Higenamine on the Rat
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Hong YS, Pae YS, Sung NE
- KMID: 1965658
- Ewha Med J.
- 1985 Sep;8(3):165-170.
- doi: 10.12771/emj.1985.8.3.165
The effect of intraperitonelly administered higenamine on the cytochrome P -450, b5, P-nitroanisole-O-demethylase and lipid peroxidation in the rat hepatic microsomes were determined. The following results were obtained ; 1)... -
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- Induction of Hepatic Microsomal UDP-Glucuronosyltransferase Activity in Nifedipine Treated Rats
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Hong YS, Pae YS
- KMID: 1965213
- Ewha Med J.
- 1990 Jun;13(2):45-51.
- doi: 10.12771/emj.1990.13.2.45
UDP-Glucuronosyltransferase(UDPGT) activity was studies in hepatic microsomal preparation from rats treated with nifedipine. The substrates 1-naphthol, P-nitrophenol, 4-methyl-umbelliferone and bilirubine were used. With 1-naphthol, nifedipine 2 and 4 weeks treatment... -
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- Developing Home Page for Ewha Womans University College of Medicine on the World Wide Web
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Byun SW, Kim SC, Lee SC, Pae YS
- KMID: 2170964
- Ewha Med J.
- 1998 Dec;21(4):263-266.
- doi: 10.12771/emj.1998.21.4.263
OBJECTIVES: Experience in development of home pages for Ewha Womans University College of Medicine were documented to present references for future development of informatics media. METHODS: Development principles were established for... -
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- The Effects of Vitamin Antioxidants on Lipid Peroxidation in Carbon Tetrachloride, Phenobarbital and Artemisia Messes - Schmidiana Var Viridis - Preteated Rats Liver Microsomes
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Han EK, Hong YS, Sung HE, Pae YS
- KMID: 2009002
- Ewha Med J.
- 1983 Jun;6(2):57-64.
- doi: 10.12771/emj.1983.6.2.57
After rats were treated with CC14, phenobarbital and artemisia messes-schmiaiana var viridis(artemisia), hepatic microsomal cytochrome P-450, cytochrome b5 and lipid peroxidation were investigated. When vitamin A, C and E were... -
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- Effect of Nifedipine on Induction of Cytochrome P-450 1A1 and 2B1 in Spontaneously Hypertensive Rate
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Hong YS, Kim HL, Park HY, Pae YS, Park SS
- KMID: 1964943
- Ewha Med J.
- 1995 Sep;18(3):161-167.
- doi: 10.12771/emj.1995.18.3.161
Cytochrome P-450(CYP) enzymes are important in catalyzing the hiotransffrmation on manyendogeneous compounds and xenobiotics, including drugs and carcinogens. In the presentstudy, effect of nifedipine a voltage dependent calcium channel blocker... -
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- Studies on the Effect of CCl4, Phenobarbital and Artemisia Messes-schmidiana val viridis on Biliary Excretion in Rat
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Pae YS
- KMID: 1967725
- Ewha Med J.
- 1983 Mar;6(1):17-22.
- doi: 10.12771/emj.1983.6.1.17
After animals were treatd with CCl4, histological changes were shown in the endoplasmic reticulum, and also microsomal activity was decreased and hepatic necrosis, lipid peroxidation in the liver were repoted.... -
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- The role of lipid peroxidation and glutathione on the glycochenodeoxycholic acid-induced cell death in primary cultured rat hepatocytes
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Chu SH, Park WM, Lee KE, Pae YS
- KMID: 1982598
- Korean J Physiol Pharmacol.
- 2000 Apr;4(2):121-127.
Intracellular accumulation of bile acids in the hepatocytes during cholestasis is thought to be pathogenic in cholestatic liver diseases. The objective of this study was to determine the role of lipid peroxidation and... -
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- Effect of Ethanol on the Neuronal Viability and Neurite Outgrowth in Primary Cultures of Rat Hippocampus
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Lee KE, Pae YS
- KMID: 2078828
- Ewha Med J.
- 1995 Dec;18(4):335-342.
- doi: 10.12771/emj.1995.18.4.335
Corrent information from studies in animal models indicates that perinatal exposure to atcohol produces a variety of damaging consequences in the central nervous system. These mayresult from direct neurotoxic effects... -
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- Glycochenodeoxycholic acid induces cell death in primary cultured rat hepatocyte: Apoptosis and necrosis
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Chu SH, Park WM, Lee KE, Pae YS
- KMID: 2071559
- Korean J Physiol Pharmacol.
- 1999 Dec;3(6):565-570.
Intracellular accumulation of bile acids in the hepatocytes during cholestasis is thought to be pathogenic in cholestatic liver injury. Due to the detergent-like effect of the hydrophobic bile acids, hepatocellular injury has been... -
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- The Effects in Colonic Body Temperature in Rats Injected Intracerebrally with PCPA & 5,7-DHT
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Pae YS, Park HY
- KMID: 1965084
- Ewha Med J.
- 1993 Dec;16(4):331-336.
- doi: 10.12771/emj.1993.16.4.331
Simonic(1988) have investigated that hypothermic effect of oholinornimetics is mediated through an activation of muscarine cholinergic receptors. And also, Yamada(1987) injected trytamine into the lateral cerebroventricle in mice and observed... -
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- The Role of the Central Parasympathetic Nervous System in Modulating Glucose Metabolism in Streptozotocin-induced Diabetic Rats
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Lee KE, Pae YS
- KMID: 1964933
- Ewha Med J.
- 1995 Jun;18(2):97-103.
- doi: 10.12771/emj.1995.18.2.97
Insulin controls the levels of blood sugar by inhibiting glucose release from liver and by stimulating glucose utilization in muscle and adipose tissues. In addition to its peripheral effects, insulin... -
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- The Effect of Unilateral Orbital Enucleation on Acetylcholine and Muscarinic Receptors in Visual Pathway, and Physical Activity of Rats
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Kim YH, Pae YS, Cho BC
- KMID: 2123358
- J Korean Ophthalmol Soc.
- 1995 May;36(5):855-867.
Acetylcholine is one of the major neurotransmitters in visual system of rats. Cholinergic, serotonergic and gamma-aminobutyric acid(GABA) ergic projections are known as modulators of visual processing. The purpose of this... -
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- Differential effect of homocysteic acid and cysteic acid on changes of inositol phosphates and (Ca2+)i in rat cerebellar granule cells
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Kim WK, Pae YS
- KMID: 2071522
- Korean J Physiol Pharmacol.
- 1998 Feb;2(1):41-48.
The present study was undertaken to characterize homocysteic acid (HCA)-and cysteic acid (CA)mediated formation of inositol phosphates (InsP) in primary culture of rat cerebellar granule cells. HCA and CA stimulated InsP formation in... -
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- Effects on 5-HT and Ach in the Rat by the I.C.V Injection of PCPA
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Pae YS
- KMID: 1965083
- Ewha Med J.
- 1993 Dec;16(4):321-330.
- doi: 10.12771/emj.1993.16.4.321
PCPA is a drug which depletes serotonin by inhibiting tryptophan hydroxylase activity. Recent evidence indicates that the ascending cholinergic projection from the basal forebrain and ascending serotonergic projections from the brain... -
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- Effect of adenosine on the release of (3H)-5-hydroxytryptamine during glucose/oxygen deprivation from rat hippocampal slices
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Lee KE, Cha KE, Pae YS
- KMID: 2285183
- Korean J Physiol Pharmacol.
- 1997 Dec;1(6):657-664.
The effects of adenosine, adenosine A1 receptor antagonist (DPCPX), or NMDA receptor antagonist (APV) on the spontaneous release of (3H)-5-hydroxytryptamine ((3H)-5-HT) during normoxic/normoglycemic or hypoxic/hypoglycemic period were studied in the rat hippocampal slices. The... -
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- Effect of Naloxone on the Cerebral Ischemia of the Rats
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Lee CH, Lee GY, Kim CH, Pae YS
- KMID: 2170842
- Ewha Med J.
- 1990 Dec;13(4):293-300.
- doi: 10.12771/emj.1990.13.4.293
Brain ischemia due to a critical reduction in cerebral blood flow is a common cause of irreversible brain damage. Ischemia is invariably accompanied by an increase in tissue lactate concentration... -
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