- The Effect of Diphenylhydantoin on the Action of Ouabain
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Kang SK, Park OK
- KMID: 2229702
- Korean Circ J.
- 1971 Dec;1(2):23-26.
- doi: 10.4070/kcj.1971.1.2.23
The effect of diphenylhydantoin on LD 50 of ouabain was investigated in frogs, using "one hour frog method". LD50 of ouabain in control group was 1.90 microg/10g. A dose of... -
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- The effects of ouabain on the ERG c-wave
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Kim HK
- KMID: 1735005
- Korean J Ophthalmol.
- 1987 Dec;1(2):84-89.
- doi: 10.3341/kjo.1987.1.2.84
ID clarify the effects of ouabain on the ERG c-wave, isolated chick retinas were exposed to different concentrations of ouabain and the results noted. Although the c-wave was abolished at... -
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- Effect of Ascorbic Acid on Corneal Endothelial Function
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Kim KS
- KMID: 2124721
- J Korean Ophthalmol Soc.
- 2000 May;41(5):1040-1046.
It has been reported that ascorbic acid[AA]appears to be actively taken up by the corneal endothelium and protect the endothelium against harmful effects of the oxidative reactions. To investigate the... -
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- Effects of Panax Ginseng on ATPase Activity of Mitochondrial Fraction from Rabbit Retina and Ciliary Epithelium
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Lee CS
- KMID: 2107057
- J Korean Ophthalmol Soc.
- 1974 Mar;15(1):45-56.
Recently it was introduced that panax ginseng enhanced the ATPase activity and antagonized the inhibited ATPase activity induced by some drugs. The author performed this experiment in order to investigate... -
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- Time-Related Alterations of Endogenous Ouabain in DOCA-Salt Hypertensive Rats
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Park CG, Hong SJ, Suh SY, Lim HE, Kim JW, Seo HS, Oh DJ, Ro YM
- KMID: 2227172
- Korean Circ J.
- 2004 Dec;34(12):1216-1222.
- doi: 10.4070/kcj.2004.34.12.1216
BACKGROUND AND OBJECTIVES: Controversy exists regarding the role of endogenous ouabain in the pathogenesis of DOCA-salt induced hypertension. The purpose of this study was to investigate the role of endogenous... -
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- Effect of Intracerebroventricular Digitalis on Cardiovascular System of Rabbits
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Song JW, Kang SS, Woo JH
- KMID: 2187642
- J Korean Neurosurg Soc.
- 1989 Feb;18(2):235-244.
Influences of intracerebroventricular(icv) ouabain on cardiovascular system and on pressor response to raised intracranial pressure(ICP) were investigated in urethane-anesthetized rabbits. Intravenous(iv) 40 microgram/kg ouabain did not affect blood pressure of... -
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- Effect of Ouabain on Intraocular Pressure in Rabbits
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Han KS
- KMID: 2106999
- J Korean Ophthalmol Soc.
- 1970 Dec;11(4):13-15.
Effect of Ouabain administration on aqueous humor dynamics were studied in albino rabbits. Intravenous injection of 0.1 mg/kg of ouabain in 10 rabbits produced significant reduction of intraocular pressure. The... -
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- Influence of Intracerebroventricularly-administered Ouabain on Renal Nerve Activity in Rabbits
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Lim YC
- KMID: 2275067
- Chonnam Med J.
- 1996 Dec;32(2):219-226.
Central nervous system is involved with the regulation of renal function either through nerual mechanisms or humoral mechanisms. Intracerebroventricularly-administred (icv) ouabain has been shown to elicits antidiuresis and antinatriuresis in... -
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- cAMP induction by ouabain promotes endothelin-1 secretion via MAPK/ERK signaling in beating rabbit atria
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Peng LQ, Li P, Zhang QL, Hong L, Liu LP, Cui X, Cui BR
- KMID: 2150468
- Korean J Physiol Pharmacol.
- 2016 Jan;20(1):9-14.
- doi: 10.4196/kjpp.2016.20.1.9
Adenosine 3',5'-cyclic monophosphate (cAMP) participates in the regulation of numerous cellular functions, including the Na(+)-K(+)-ATPase (sodium pump). Ouabain, used in the treatment of several heart diseases, is known to increase... -
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- Studies on Na-K-ATPase Activity of Goat Cerebral Cortex
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Hong IB, Lee YW
- KMID: 2187149
- J Korean Neurosurg Soc.
- 1979 Sep;8(2):307-316.
The author had investigated the effects of Na-K-ATPase activity on the incubation period, ATP and enzyme concentration, and various electrolytes in brain homogenate of Korean native goat. The results were... -
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- Effect of Carbamazepine on the Ouabain-Induced Arrhythmia in Rabbits
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Kim EH, Ha JH, Lee KY, Kim WJ
- KMID: 2373892
- Yeungnam Univ J Med.
- 1986 Dec;3(1):279-285.
- doi: 10.12701/yujm.1986.3.1.279
Carbamazepine is a derivative of iminostilbene with carbamoyl group and related chemically to the tricyclic antidepressants. Carbamazepine has been introduced for treatment of trigeminal neuralgia. Recently it is used as an... -
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- Role of alpha-Adrenergic Receptors in the Development of Delayed Afterdepolarization
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Kim JH, Joo KC, Ju JM, Kook H, Shin DH, Cho JG
- KMID: 1881499
- Korean Circ J.
- 1996 Oct;26(5):1048-1057.
- doi: 10.4070/kcj.1996.26.5.1048
BACKGROUND: To investigate the role of alpha-adrenergic receptors in the development of delayed afterdepolarization, the effect of alpha-adrenoceptor stimulation and blockade on ouabain induced delayed afterdepolarization(DDAD) was examined in rabbit... -
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- The Effect of Saponin on the Na+ - K+ Activated ATPase of Cattle Lens Epithelial Cell
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Chang WG, Koo KL, Kang BN
- KMID: 2336546
- J Korean Ophthalmol Soc.
- 1992 Jan;33(1):60-67.
The effect of saponin on the Na+ - K+ ATPase of anterior capsule and epithelium of cattle lens has been investigated. The experiment also designed to determine the cation of... -
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- Quantitative Measurement of Membrane Na+-K+ ATPase Activity using Thallium-201: Comparison with Rubidium-86
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Lee JT, Lee IK, Sohn SK, Lee KB
- KMID: 2078673
- Korean J Nucl Med.
- 1998 Apr;32(2):121-128.
PURPOSE: Na+-K+ ATPase Activity has beem estimated by the degree of inhibition of cation transport by cardiac glycosides (ouabain) using Rb-86 as a substrate. The biological characterist-Isc of T1-201 is... -
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- Altered Vascular Response to the K+induced Vasorelaxation in Aortic Smooth Muscle of Renal Hypertensive Rats
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Jun JY, Yeum CH, Yoon PJ, Liee JH, Choi HH, Park YW, Kim JH
- KMID: 2298026
- Korean Circ J.
- 2000 Aug;30(8):980-988.
- doi: 10.4070/kcj.2000.30.8.980
BACKGROUND: An increase of the extracellular K+concentrations up to about 8 mM in the isolated vessels causes relaxation in pre-contracted state. In order to elucidate the mechanisms of K+induced relaxation... -
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- Damage of Spiral Ganglion Cell Induced by Ouabain Application in Cat
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Kim BY, Bae WY, Kim JR, Lee TH
- KMID: 1726625
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2014 Sep;57(9):589-595.
- doi: 10.3342/kjorl-hns.2014.57.9.589
BACKGROUND AND OBJECTIVES: Auditory neuropathy is a hearing disorder characterized by the absence or the marked impairment of the auditory brainstem responses with the preservation of the cochlear microphonics (CMs)... -
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- Effect of Carteolol Hydrochloride on Sodium-Potassium Activated ATPase in Cattle Lena Epithelial Cell Membrane
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Lee KH, Chang WG, Kang BN
- KMID: 2122943
- J Korean Ophthalmol Soc.
- 1990 Feb;31(2):207-213.
The effect of Carteolol hydrocholride on the Na-K ATPase of anterior capsule and epithelium of cattle lens has been investigated. The experiments were also designed to determine the action of... -
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- Impaired Endothelium-Dependent Relaxation by Alternating Protein Kinase C and Na+-K+ ATPase in Isolated Rabbit Corpus Cavernosum Exposed to Elevated Glucose
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Jung SY, Hwang TK, Yoon JY
- KMID: 1991324
- Korean J Urol.
- 1997 May;38(5):463-472.
Impaired endothelium dependent relaxation occurs in diabetic rabbit corpus cavernosum and normal corpus cavernosum exposed to elevated glucose. Elevation of glucose can change the activities of two key enzymes, protein... -
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- Moderate elevation of extracellular K+ concentration induces vasorelaxation in isolated rat, rabbit and human cerebral arteries: Role of Na pump and Ba-sensitive process
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Kim DH, Kim SJ, Lee SJ, Park SJ, Kim KW
- KMID: 2071829
- Korean J Physiol Pharmacol.
- 1998 Dec;2(6):705-714.
Cerebral blood vessels relax when extracellular K+ concentrations ((K+))e are elevated moderately (2~15 mM, K+-induced vasorelaxation). We have therefore studied the underlying mechanism for this K+-induced vasorelaxation in the isolated middle cerebral arteries (MCAs).... -
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- Effects of Na+, K(+)-pump inhibitors on acetylcholine-induced relaxation in the rabbit aorta
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Lee YH, Ahn DS, Song HJ, Kim YH, Kim HS, Ahn SH, Kang BS
- KMID: 1117759
- Yonsei Med J.
- 1992 Mar;33(1):8-13.
- doi: 10.3349/ymj.1992.33.1.8
The purpose of this study was to investigate the effects of inhibitors of the Na+, K(+)-pump and membrane depolarizing agents on endothelium-dependent acetylcholine-induced relaxation in the rabbit thoracic aorta. Aortic... -
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