- Morphological and electrophysiological studies of the organ of corti following various noise exposure
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Kim HN, Chung MH, Moon TY, Shim YJ, Kim YM
- KMID: 1684381
- Korean J Otolaryngol-Head Neck Surg.
- 1991 Dec;34(6):1120-1151.
No abstract available. -
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- Development of Vestibular Organ and Cochlea
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Hwang CH
- KMID: 1722547
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2010 May;53(5):265-274.
- doi: 10.3342/kjorl-hns.2010.53.5.265
Inner ear is an important organ that is responsible for balance and hearing. It is composed of two complicated major subunits, vestibular organ and cochlea. During development, both functional units... -
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- Organotypic Culture of Organ of Corti with Floating Drop Method from Newborn Rat
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Cho CG, Chung JW, Kim HJ, Lee KS
- KMID: 1559724
- Korean J Otolaryngol-Head Neck Surg.
- 1998 Jul;41(7):823-829.
BACKGROUND AND OBJECTIVES: Organotypic culture of organ of Corti maintains the basic organization of the spiral lamina and can conserve several factors responsible for the neuronal growth of the nervous... -
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- Measurement of the Mechanical Deformation of Organ of Corti in a Model of Acute Endolymphatic Hydrops
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Lee SH, Kalinec F
- KMID: 2155057
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2016 Feb;59(2):110-119.
- doi: 10.3342/kjorl-hns.2016.59.2.110
BACKGROUND AND OBJECTIVES: Endolymphatic hydrops has been considered as an important histologic substrate of Meniere's disease. A permanent displacement of basilar membrane (BM) by increased endolymphatic pressure has been thought... -
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- Endogenous Stem Cells in the Ear
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Park KH
- KMID: 1798110
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2013 Dec;56(12):749-753.
- doi: 10.3342/kjorl-hns.2013.56.12.749
Basically stem cells have characteristics of multi-potency, differentiation into multiple tissue types, and self-renew through proliferation. Recent advances in stem cell biology can make identifying the stem-cell like cells in... -
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- Updates in Noise Induced Hearing Loss
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Shin SO
- KMID: 1726624
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2014 Sep;57(9):584-588.
- doi: 10.3342/kjorl-hns.2014.57.9.584
Noise-induced hearing loss could be caused by mechanical destruction of the delicate membranes of the inner ear, hair cells and supporting structures of the organ of Corti, and by intense... -
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- Outward Rectifying Current in Isolated Deiters' Cells from Guinea Pig Cochlea
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Kim HJ, Ahn JH, Kim WT, Leem CH, Chung JW, Lee KS
- KMID: 1887269
- Korean J Otolaryngol-Head Neck Surg.
- 2002 Jun;45(6):550-556.
BACKGROUND AND OBJECTIVES: The Deiters' cell is one of the supporting cells in the organ of Corti and is known to possibly regulate the signal transduction pathway in the organ... -
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- Apoptotic Pattern of Cochlear Outer Hair Cells and Frequency-specific Hearing Threshold Shift in Noise-exposed BALB/c Mice
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Lim HW, Choi SH, Kang HH, Ahn JH, Chung JW
- KMID: 1486058
- Clin Exp Otorhinolaryngol.
- 2008 Jun;1(2):80-85.
- doi: 10.3342/ceo.2008.1.2.80
OBJECTIVES: Apoptosis of outer hair cell (OHC) can be identified through nuclear staining by specific nuclear changes. The change of filamentous actin (F-actin) is also involved in early cell death... -
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- Apoptosis Progression in the Hair Cells in the Organ of Corti of GJB2 Conditional Knockout Mice
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Zhang Y, Zhang X, Li L, Sun Y, Sun J
- KMID: 2134595
- Clin Exp Otorhinolaryngol.
- 2012 Sep;5(3):132-138.
- doi: 10.3342/ceo.2012.5.3.132
OBJECTIVES: Apoptosis may play an important role in the mechanism underlying the GJB2 gene conditional knockout (cCx26) mice cochlear cell death. The objective of this study was to explore the... -
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- Potassium Currents in Isolated Deiters' Cells of Guinea Pig
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Chung JW, Nam EC, Kim WT, Youm JB, Leem CH
- KMID: 2285482
- Korean J Physiol Pharmacol.
- 2013 Dec;17(6):537-546.
- doi: 10.4196/kjpp.2013.17.6.537
Deiters' cells are the supporting cells in organ of Corti and are suggested to play an important role in biochemical and mechanical modulation of outer hair cells. We successfully isolated... -
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- Role of Endogenous Bone Marrow Stem Cells Mobilization in Repair of Damaged Inner Ear in Rats
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Elbana AM, Abdel-Salam S, Morad GM, Omran AA
- KMID: 2380809
- Int J Stem Cells.
- 2015 Nov;8(2):146-154.
- doi: 10.15283/ijsc.2015.8.2.146
BACKGROUND AND OBJECTIVES: The utilization of the stem cells is widely used in the last few years in different fields of medicine, either by external transplantation or endogenous mobilization, most... -
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- Comparison of Cochlear Morphology and Apoptosis in Mouse Models of Presbycusis
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Park SN, Back SA, Park KH, Kim DK, Park SY, Oh JH, Park YS, Yeo SW
- KMID: 2278608
- Clin Exp Otorhinolaryngol.
- 2010 Sep;3(3):126-135.
OBJECTIVES: Morphological studies on presbycusis, or age-related hearing loss, have been performed in several different strains of mice that demonstrate hearing loss with auditory pathology. The C57BL/6 (C57) mouse is... -
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- The Morphological Changes of the Cochlea in the Guinea Pig after Single Blast Wave Stimulation
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Cho CS, Park KY, Kim JY, Kim JW, Lee GW, Lee CH, Lee BK
- KMID: 2141374
- Korean J Otolaryngol-Head Neck Surg.
- 2002 Sep;45(9):839-845.
BACKGROUND AND OBJECTIVES: The mechanism of the noise damage to the cochlea is not fully understood in spite of many studies. The morphological changes in a noise stimulated model show... -
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- Biological Analysis of a New Spontaneous Mutant Mouse Showing Deafness and Circling Behavior
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Cho DY, Kim MS, Chung WH, Ryoo ZY, Hong SH
- KMID: 2276097
- Korean J Otolaryngol-Head Neck Surg.
- 2004 Feb;47(2):115-126.
BACKGROUND AND OBJECTIVES: Deafness is the most common sensory deficit and hereditary defect in human populations. The present study investigated the causative gene in circling mice using the complementation test.... -
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- Cochlear Pathology in Experimental Otitis Media with Effusion ofGuinea Pig Caused by Endotoxin
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Jung HH, Kim YH, Sung TH, Jung DK
- KMID: 2274518
- Korean J Otolaryngol-Head Neck Surg.
- 1998 Dec;41(12):1527-1535.
BACKGROUND AND OBJECTIVES: Injection of endotoxin into the middle ear of experimental animals results in otitis media with effusion and transient reversible hearing loss, which occurs in the higher concentration... -
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- The Effect of Intratympanically Delivered Lidocaine on Otoacoustic Emission in Tinnitus Patients
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Jang MH, Goh EK, Park JH, Lee SH, Chon KM
- KMID: 2074394
- Korean J Otolaryngol-Head Neck Surg.
- 2000 Sep;43(9):931-936.
BACKGROUND AND OBJECTIVES: Tinnitus is one of the most obscure otological pathologies. There is no universally proved treatment modality for tinnitus. Intratympanic lidocaine injection is one of the therapeutic trials.... -
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- An Experimental Study on Bisphosphonates Ototoxicity
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Park IS, Kim HJ, Lim HJ
- KMID: 2274403
- Korean J Otolaryngol-Head Neck Surg.
- 1998 Mar;41(3):307-312.
BACKGROUND AND OBJECTIVES: Bisphosphonates are known to inhibit bone resorption, and some researchs are also undergoing on their protective effect against localized bone resorprion in aural cholesteatoma. However, ototoxicity has... -
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- A Study of the Expression of Heat Shock Protein 72 in Guinea PigCochlea after Cisplatin Injection
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Yu WS, Oh SH, Kim CS
- KMID: 2274468
- Korean J Otolaryngol-Head Neck Surg.
- 1998 Sep;41(9):1105-1110.
BACKGROUND AND OBJECTIVES: Several studies have attempted to show the reasons for ototoxicity induced by cisplatin, but the cochlear ototoxicity remained poorly understood. Recently, it is considered that free radicals... -
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- The Effects of Neurotransmitters on the Ion Channels in the Isolated Deiters'Cells of Guinea Pig Cochlea
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Nam EC, Kim WT, Leem CH, Chung JW
- KMID: 1923102
- Korean J Otolaryngol-Head Neck Surg.
- 2003 Mar;46(3):191-197.
BACKGROUND AND OBJECTIVES: The supporting cells in the organ of Corti help to maintain the structural integrity of the organ, but it has been suggested that they also actively participate... -
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- Effect of Ebselen on Noise Induced Cochlear Damage
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Park YH, Lee YW, Park SW, Koo BS, Kim YM, Rha KS, Park CI
- KMID: 2276488
- Korean J Otolaryngol-Head Neck Surg.
- 2005 Oct;48(10):1211-1218.
BACKGROUND AND OBJECTIVES: With the advancement of modern civilization and mechanical development of society, the prevalence of noiseinduced hearing loss is increasing. There were some suggestions that noise-induced hearing loss... -
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