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The Rise of On-Demand Research and Specific Applications: Optogenetics in Urology

Kim KH

No abstract available.
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Optogenetic and Chemogenetic Approaches for Studying Astrocytes and Gliotransmitters

Bang J, Kim HY, Lee H

The brain consists of heterogeneous populations of neuronal and non-neuronal cells. The revelation of their connections and interactions is fundamental to understanding normal brain functions as well as abnormal changes...
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Optogenetics Applications for Treating Spinal Cord Injury

Ahmad A, Ashraf S, Komai S

Cases of spinal cord injury (SCI) are increasing all over the world; and in USA alone, there are 273,000 patients, which not only leads to morbidity and mortality but also...
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A new approach to urinary bladder control with optogenetics

Park E, Lee KS

No abstract available.
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Optogenetic Glia Manipulation: Possibilities and Future Prospects

Cho WH, Barcelon E, Lee SJ

Our brains are composed of two distinct cell types: neurons and glia. Emerging data from recent investigations show that glial cells, especially astrocytes and microglia, are able to regulate synaptic...
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Optical Tools to Investigate Cellular Activity in the Intestinal Wall

Boesmans W, Hao MM, Berghe PV

  • KMID: 2433473
  • J Neurogastroenterol Motil.
  • 2015 Jul;21(3):337-351.
  • doi: 10.5056/jnm15096
Live imaging has become an essential tool to investigate the coordinated activity and output of cellular networks. Within the last decade, 2 Nobel prizes have been awarded to recognize innovations...
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Advances in the simulation of light–tissue interactions in biomedical engineering

Krasnikov , Seteikin A, Roth B

Monte Carlo (MC) simulation for light propagation in scattering and absorbing media is the gold standard for studying the interaction of light with biological tissue and has been used for...
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Brain Stimulation and Modulation for Autism Spectrum Disorder

Kim T, Ryu JE, Bahn GH

Autism spectrum disorder (ASD) is characterized by a range of conditions including impairments in social interaction, communication, and restricted and repetitive behaviors. Pharmacological treatments can improve some symptoms of ASD,...
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Inhibition of anterior cingulate cortex excitatory neuronal activity induces conditioned place preference in a mouse model of chronic inflammatory pain

Kang SJ, Kim S, Lee J, Kwak C, Lee K, Zhuo M, Kaang BK

The anterior cingulate cortex (ACC) is known for its role in perception of nociceptive signals and the associated emotional responses. Recent optogenetic studies, involving modulation of neuronal activity in the...
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Optogenetic Rescue of Locomotor Dysfunction and Dopaminergic Degeneration Caused by Alpha-Synuclein and EKO Genes

Qi C, Varga S, Oh SJ, Lee CJ, Lee D

α-Synuclein (α-Syn) is a small presynaptic protein and its mutant forms (e.g. A53T) are known to be directly associated with Parkinson's disease (PD). Pathophysiological mechanisms underlying α-Syn-mediated neurodegeneration in PD...
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Neuroimmune interactions and kidney disease

Hasegawa S, Inoue T, Inagi R

The autonomic nervous system plays critical roles in maintaining homeostasis in humans, directly regulating inflammation by altering the activity of the immune system. The cholinergic anti-inflammatory pathway is a well-studied...
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Pulse-train Stimulation of Primary Somatosensory Cortex Blocks Pain Perception in Tail Clip Test

Lee S, Hwang E, Lee D, Choi JH

Human studies of brain stimulation have demonstrated modulatory effects on the perception of pain. However, whether the primary somatosensory cortical activity is associated with antinociceptive responses remains unknown. Therefore, we...
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