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The Role of Two Human Milk Oligosaccharides, 2′-Fucosyllactose and Lacto-N-Neotetraose, in Infant Nutrition

Hegar B, Wibowo Y, Basrowi RW, Ranuh RG, Sudarmo SM, Munasir Z, Atthiyah A, Widodo AD, Supriatmo , Kadim M, Suryawan A, Diana NR, Manoppo C, Vandenplas Y

Human breast milk contains numerous biomolecules. Human milk oligosaccharides (HMOs) are the third most abundant component of breast milk, after lactose and lipids. Amongst the synthetized HMOs, 2′-fucosyllactose (2′-FL) and...
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Irritable Bowel Syndrome

Kim JH, Jee SR

Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder. Its diagnosis is based on symptoms, and the Rome IV criteria are recognized as the gold diagnostic standard. The Korean...
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Review of the Clinical Practice Guidelines for Irritable Bowel Syndrome in Korea, 2017 Revised Edition

Jung HK

This guidance is an updated version of the irritable bowel syndrome (IBS) guidelines based on evidence-based medicine. IBS is a common chronic gastrointestinal syndrome that occurs in approximately 10% of...
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Use of Dietary Management in Irritable Bowel Syndrome: Results of a Survey of Over 1500 United States Gastroenterologists

Lenhart A, Ferch C, Shaw M, Chey WD

  • KMID: 2417389
  • J Neurogastroenterol Motil.
  • 2018 Jul;24(3):437-451.
  • doi: 10.5056/jnm17116
BACKGROUND/AIMS: Dietary therapy is increasingly used to manage gastrointestinal (GI) symptoms in patients with irritable bowel syndrome (IBS). We aim to gauge United States gastroenterologists’ perceptions of dietary therapies for...
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Clinical Practice Guidelines for Irritable Bowel Syndrome in Korea, 2017 Revised Edition

Song KH, Jung HK, Kim HJ, Koo HS, Kwon YH, Shin HD, Lim HC, Shin JE, Kim SE, Cho DH, Kim JH, Kim HJ, The Clinical Practice Guidelines Group Under the Korean Society of Neurogastroenterology and Motility

  • KMID: 2413096
  • J Neurogastroenterol Motil.
  • 2018 Apr;24(2):197-215.
  • doi: 10.5056/jnm17145
In 2011, the Korean Society of Neurogastroenterology and Motility (KSNM) published clinical practice guidelines on the management of irritable bowel syndrome (IBS) based on a systematic review of the literature....
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An Update on Gut Microbiota and Infant's Health

Manzoor Z, Koh YS

Childhood malnutrition is a global problem and one of the leading cause of stunted growth, and responsible for the death of millions of children every year. Although extensive efforts have...
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Effect of dual-type oligosaccharides on constipation in loperamide-treated rats

Han SH, Hong KB, Kim EY, Ahn SH, Suh HJ

BACKGROUND/OBJECTIVES: Constipation is a condition that can result from intestinal deformation. Because humans have an upright posture, the effects of gravity can cause this shape deformation. Oligosaccharides are common prebiotics...
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Validation of the Korean coefficient for the modification of diet in renal disease study equation

Oh YJ, Cha RH, Lee SH, Yu KS, Kim SE, Kim H, Kim YS

BACKGROUND/AIMS: Race and ethnicity are important determinants when estimatingglomerular filtration rate (GFR). The Korean coefficients for the isotope dilution mass spectrometry (IDMS) Modification of Diet in Renal Disease (MDRD) Study...
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Diet and Nutritional Management in Functional Gastrointestinal Disorder: Irritable Bowel Syndrome

Kim JH

Irritable bowel syndrome (IBS) is a multifactorial disorder with the pathogenesis of abnormal gastrointestinal motility, low-grade inflammation, visceral hypersensitivity, communication in the gut-brain axis, and so on. Traditionally, IBS has...
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The Low FODMAP Diet and Its Application in East and Southeast Asia

Iacovou M, Tan V, Muir JG, Gibson PR

  • KMID: 2381294
  • J Neurogastroenterol Motil.
  • 2015 Oct;21(4):459-470.
  • doi: 10.5056/jnm15111
There is growing interest in using food choice/dietary change to influence clinical outcomes in patients with irritable bowel syndrome (IBS). The low fermentable oligo-, di-, mono-saccharides, and polyols (FODMAPs) diet...
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Carbohydrates as food allergens

Soh JY, Huang CH, Lee BW

The literature supports the notion that carbohydrate epitopes, on their own, do not contribute significantly to the induction of allergic reactions. They bind weakly to IgE antibodies and have been...
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Delayed Anaphylaxis to Red Meat Associated With Specific IgE Antibodies to Galactose

Wen L, Zhou J, Yin J, Sun JL, Sun Y, Wu K, Katial R

A novel delayed anaphylactic reaction to red meat, associated with tick bites and IgE antibodies against galactose-alpha-1, 3-galactose (alpha-gal), was reported in 2009 in the US, Australia and Europe. In...
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Current Issues on Irritable Bowel Syndrome: Diet and Irritable Bowel Syndrome

Kim JH, Sung IK

Irritable bowel syndrome (IBS) is one of the most prevalent functional gastrointestinal disorders. It is a multifactorial disorder with its pathogenesis attributed to abnormal gastrointestinal motility, low-grade inflammation, visceral hypersensitivity,...
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Oxidative response of neutrophils to platelet-activating factor is altered during acute ruminal acidosis induced by oligofructose in heifers

Concha C, Carretta M, Alarcon P, Conejeros , Gallardo D, Hidalgo AI, Tadich N, Caceres DD, Hidalgo MA, Burgos RA

Reactive oxygen species (ROS) production is one of the main mechanisms used to kill microbes during innate immune response. D-lactic acid, which is augmented during acute ruminal acidosis, reduces platelet...
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Conformation and Linkage Studies of Specific Oligosaccharides Related to H1N1, H5N1, and Human Flu for Developing the Second Tamiflu

Yoo E

  • KMID: 2170647
  • Biomol Ther.
  • 2014 Mar;22(2):93-99.
The interaction between viral HA (hemagglutinin) and oligosaccharide of the host plays an important role in the infection and transmission of avian and human flu viruses. Until now, this interaction...
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Quantitative Assessment Technology of Small Animal Myocardial Infarction PET Image Using Gaussian Mixture Model

Woo SK, Lee YJ, Lee W, Kim MH, Park JA, Kim JS, Kim JG, Kang JH, Ji YH, Choi CW, Lim SM, Kim KM

  • KMID: 2307129
  • Korean J Med Phys.
  • 2011 Mar;22(1):42-51.
Nuclear medicine images (SPECT, PET) were widely used tool for assessment of myocardial viability and perfusion. However it had difficult to define accurate myocardial infarct region. The purpose of this...
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Comparison of Gefitinib versus Docetaxel in Patients with Pre-Treated Non-Small Cell Lung Cancer (NSCLC)

Hirsh V

More effective treatments in first, second, and third-line of metastatic non-small cell lung cancer (NSCLC) enable patients to live longer, with a better quality of life (QOL). Especially epidermal growth...
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Dose-response assessment of the anti-cancer efficacy of soy isoflavones in dimethylhydrazine-treated rats fed 6% fructooligosaccharide

Sung HY, Choi YS

  • KMID: 2313350
  • Nutr Res Pract.
  • 2008 Jun;2(2):55-61.
We investigated the combinatorial effects of different doses of dietary soy isoflavones (SI) and fructooligosaccharide (FOS) in a rat model of colon cancer. We hypothesized that increased bioavailability of SI...
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Effects of sn-2 palmitic acid-fortified vegetable oil and fructooligosaccharide on calcium metabolism in growing rats fed casein based diet

Lee YS, Kang EY, Park MN, Choi YY, Jeon JW, Yun SS

  • KMID: 2313341
  • Nutr Res Pract.
  • 2008 Mar;2(1):3-7.
This study was carried out to investigate the efficacy of sn-2 palmitic acid-fortified vegetable oil (Sn2PA) on calcium absorption and to confirm the synergistic effects of fructooligosaccharide on calcium absorption....
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Blood glucose analysis in patients on continuous ambulatory peritoneal dialysis with Icodextrin

Yoon SH, Choi NW, Yun SR

  • KMID: 2256255
  • Korean J Med.
  • 2008 Feb;74(2):170-175.
BACKGROUND/AIMS: Icodextrin (glucose polymer) is metabolized by a-amylase to oligosaccharides such as maltose and maltotriose. The presence of these metabolites could have an effect on the enzymatic glucose measurement especially...
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