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Influence on the bone mineral density and bone metabolism marker after the interruption and reinitiation of monthly minodronate therapy in postmenopausal women with osteoporosis

Okimoto N, Arita S, Akahoshi S, Baba K, Fukuhara S, Ishikura T, Yoshioka T, Fuse Y, Okamoto K, Menuki K, Sakai A

OBJECTIVES: The purpose of this study was to investigate the influences of interruption and reinitiation of monthly minodronate therapy on the bone mineral density (BMD) and bone metabolism markers in...
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A Novel Technique for Varus Tibial Cutting for Oxford Unicompartmental Knee Arthroplasty

Hiranaka T, Tanaka T, Fujishiro T, Okimura K, Shigemoto R, Araki S, Okada R, Nako R, Okamoto K

To reduce the stress on the medial tibial cortex and to decrease the risk of fracture, a varus cut of the tibia appears to be a reasonable alternative to the...
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Manipulation of Tibial Component to Ensure Avoidance of Bearing Separation from the Vertical Wall of Tibial Component in Oxford Unicompartmental Arthroplasty

Hiranaka T, Tanaka T, Okimura K, Fujishiro T, Shigemoto R, Araki S, Okada R, Nako R, Kamenaga T, Okamoto K

In Oxford unicompartmental knee arthroplasty, the relationship between the mobile bearing and the vertical wall of the tibial tray is important in preventing bearing dislocation. Separation of the bearing from...
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Kinematically Aligned Oxford Unicompartmental Knee Arthroplasty Using the Microplasty Instrumentation System

Hiranaka T, Fujishiro T, Koide M, Okamoto K

This technical note demonstrates kinematically aligned Oxford unicompartmental knee arthroplasty using the Microplasty instrumentation system with custom-made devices. The medial joint line is evaluated preoperatively; if it is aligned and...
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A Modified Under-Vastus Approach for Knee Arthroplasty with Anatomical Repair of Soft Tissue

Hiranaka T, Tanaka T, Fujishiro , Anjiki K, Nagata N, Kitazawa D, Kotoura K, Okamoto K

The under-vastus approach (UVA) is a modification of the conventional subvastus approach for knee arthroplasty. Our modified UVA allows the muscles to be spared while offering good exposure of the...
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Longer prolapsed rectum length increases recurrence risk after Delorme’s procedure

Tanabe T, Yamaguchi E, Nakada T, Nishio R, Okamoto K, Yamana T

Purpose: Risk factors for recurrence of rectal prolapse after surgery remain unclear. Delorme’s procedure is often selected for relatively small-sized rectal prolapse, but there are few reports discussing the association...
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Twin Rectal Tonsils Mimicking Carcinoid or Mucosa-Associated Lymphoid Tissue Lymphoma

Takehara M, Muguruma N, Kitamura S, Kimura T, Okamoto K, Miyamoto H, Bando Y, Takayama T

The rectal tonsil is a rare polypoid lesion exclusively found in the rectum and is considered a reactive proliferation of the lymphoid tissue. Although this lesion is benign, we recommend...
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The Medial Eminence Line for Predicting Tibial Fracture Risk after Unicompartmental Knee Arthroplasty

Yoshikawa , Hiranaka T, Okamoto K, Fujishiro , Hida Y, Kamenaga T, Sakai Y

Background: Tibial fracture after cementless Oxford unicompartmental knee arthroplasty (OUKA) is a rare but serious complication. It is reported more frequently in Asian countries. The aim of this retrospective study...
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Second-Look Arthroscopic Findings and Clinical Outcomes after Adipose-Derived Regenerative Cell Injection in Knee Osteoarthritis

Onoi Y, Hiranaka T, Hida Y, Fujishiro T, Okamoto K, Matsumoto T, Kuroda R

Background: To evaluate the clinical outcomes and second-look arthroscopic findings after intra-articular adipose-derived regenerative cell (ADRC) injection as treatment for knee osteoarthritis (OA). Methods: ADRCs were administered to 11 patients (19...
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Clinical Results of Dual SC Screw: A Mini-Sliding Hip Screw with an Anti-rotating Screw for Femoral Neck Fractures

Hiranaka T, Tanaka T, Okumura K, Fujishiro T, Shigemoto R, Araki S, Okada R, Nako R, Okamoto K

Background: Dual SC screw (DSCS) is a unique concept internal fixation device consisting of a sliding screw and barrel assembly that enables compression force to be applied to the femoral...
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Incidence of metastasis in circumflex iliac nodes distal to the external iliac nodes in cervical cancer

Takeshita , Todo Y, Okamoto K, Sudo S, Yamashiro , Kato H

OBJECTIVE: A causal relationship between removal of circumflex iliac nodes distal to the external iliac nodes (CINDEIN) and lower leg edema has been recently suggested. The aim of this study...
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Implications of para-aortic lymph node metastasis in patients with endometrial cancer without pelvic lymph node metastasis

Todo Y, Takeshita , Okamoto K, Yamashiro , Kato H

OBJECTIVE: The aim of this study was to confirm the incidence and implications of a lymphatic spread pattern involving para-aortic lymph node (PAN) metastasis in the absence of pelvic lymph...
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Retrospective surveillance of metabolic parameters affecting reproductive performance of Japanese Black breeding cows

Watanabe U, Takagi M, Yamato O, Otoi T, Okamoto K

This retrospective study was conducted to confirm the relationship between pre- and postpartum metabolic parameters and postpartum reproductive performance and to clarify seasonal characteristics of the metabolic parameters by using...
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Risk of lingual nerve injuries in removal of mandibular third molars: a retrospective case-control study

Tojyo I, Nakanishi , Shintani Y, Okamoto K, Hiraishi Y, Fujita S

BACKGROUND: Through the analysis of clinical data, we attempted to investigate the etiology and determine the risk of severe iatrogenic lingual nerve injuries in the removal of the mandibular third...
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A prediction model of survival for patients with bone metastasis from uterine cervical cancer

Matsumiya , Todo Y, Okamoto K, Takeshita , Yamazaki H, Yamashiro , Kato H

OBJECTIVE: The aim of the study was to establish a predictive model of survival period after bone metastasis from cervical cancer. METHODS: A total of 54 patients with bone metastasis from...
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Prognostic factors for patients with cervical cancer treated with concurrent chemoradiotherapy: a retrospective analysis in a Japanese cohort

Endo D, Todo Y, Okamoto K, Minobe S, Kato H, Nishiyama

OBJECTIVE: Concurrent chemoradiotherapy (CCRT) is the primary treatment for locally advanced cervical cancer. We studied prognostic factors for patients treated with CCRT. METHODS: We retrospectively reviewed records of 85 consecutive patients...
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Pyruvate Protects Giardia Trophozoites from Cysteine-Ascorbate Deprived Medium Induced Cytotoxicity

Raj D, Chowdhury , Sarkar R, Saito-Nakano Y, Okamoto K, Dutta S, Nozaki T, Ganguly S

Giardia lamblia, an anaerobic, amitochondriate protozoan parasite causes parasitic infection giardiasis in children and young adults. It produces pyruvate, a major metabolic product for its fermentative metabolism. The current study...
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PD-L1 expression correlated with p53 expression in oral squamous cell carcinoma

Tojyo I, Shintani Y, Nakanishi , Okamoto K, Hiraishi Y, Fujita S, Enaka M, Sato F, Muragaki Y

BACKGROUND: Programmed cell death ligand 1 (PD-L1) is an immune checkpoint molecule that attenuates the immune response. PD-L1 contributes to failed antitumor immunity; thereby, blockade of PD-L1 with monoclonal antibody...
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Therapeutic significance of full lymphadenectomy in early-stage ovarian clear cell carcinoma

Yamazaki H, Todo Y, Shimada C, Takeshita , Minobe S, Okamoto K, Yamashiro , Kato H

OBJECTIVES: This study evaluated the therapeutic significance of full lymphadenectomy in early-stage ovarian clear cell carcinoma (OCCC). METHODS: We retrospectively reviewed records of 127 consecutive patients with pT1/pT2 and M0 OCCC...
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Pretreatment risk factors for parametrial involvement in FIGO stage IB1 cervical cancer

Yamazaki H, Todo Y, Okamoto K, Yamashiro , Kato H

OBJECTIVE: All patients with stage IB1 cervical cancer do not need to undergo parametrectomy. Some low-risk criteria for parametrial involvement (PI) have been proposed based on pathological findings. The aim...
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