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Erratum: Correction of Figures. The Time Course Changes in Bone Metabolic Markers after Administering the Anti-Receptor Activator of Nuclear Factor-Kappa B Ligand Antibody and Drug Compliance among Patients with Osteoporosis

Inage K, Orita S, Yamauchi K, Sakuma Y, Kubota G, Oikawa Y, Sainoh T, Sato J, Fujimoto K, Shiga Y, Takahashi , Ohtori S

There were some mistakes in the numerical values of the graphs.
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Response to: “Long-term Outcomes of In Situ Fusion for Treating Dysplastic Spondylolisthesis”

Inage K, Orita S, Yamauchi K, Suzuki M, Sakuma Y, Kubota G, Oikawa Y, Sainoh T, Sato J, Fujimoto K, Shiga Y, Abe K, Kanamoto H, Inoue M, Kinoshita , Norimoto M, Umimura T, Takahashi , Ohtori S

No abstract available.
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Diagnosis of Lumbar Foraminal Stenosis using Diffusion Tensor Imaging

Eguchi Y, Ohtori S, Suzuki M, Oikawa Y, Yamanaka H, Tamai H, Kobayashi , Orita S, Yamauchi K, Suzuki M, Aoki Y, Watanabe A, Kanamoto H, Takahashi

Diagnosis of lumbar foraminal stenosis remains difficult. Here, we report on a case in which bilateral lumbar foraminal stenosis was difficult to diagnose, and in which diffusion tensor imaging (DTI)...
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Improvements in Intractable Lumbar and LowerExtremity Symptoms after Systemic Administration of Tocilizumab, an Anti-interleukin-6 Receptor Antibody

Sainoh T, Sainoh T, Orita S, Orita S, Miyagi M, Miyagi M, Suzuki-Narita M, Suzuki-Narita M, Sakuma Y, Sakuma Y, Oikawa Y, Oikawa Y, Kubota G, Kubota G, Sato J, Sato J, Shiga Y, Shiga Y, Fujimoto K, Fujimoto K, Eguchi Y, Eguchi Y, Koda M, Koda M, Aoki Y, Aoki Y, Akazawa T, Akazawa T, Furuya T, Furuya T, Nakamura J, Nakamura J, Takahashi H, Takahashi H, Maki S, Maki S, Inoue M, Inoue M, Kinoshita H, Kinoshita H, Norimoto M, Norimoto M, Sato T, Sato T, Sato M, Sato M, Suzuki M, Suzuki M, Enomoto K, Enomoto K, Takaoka H, Takaoka H, Mizuki N, Mizuki N, Hozumi T, Hozumi T, Tsuchiya R, Tsuchiya R, Kim G, Kim G, Otagiri T, Otagiri T, Mukaihata T, Mukaihata T, Hishiya T, Hishiya T, Ohtori S, Ohtori S, Inage K, Inage K

Study Design: Prospective cohort study (open-label, single-arm, and non-blinded). Purpose: This study aims to determine the effects of systemic administration of tocilizumab, an anti-interleukin-6 (IL-6) receptor antibody on refractory low back...
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No Acceleration of Intervertebral Disc Degeneration after a Single Injection of Bupivacaine in Young Age Group with Follow-Up of 5 Years

Ohtori S, Inoue G, Orita S, Eguchi Y, Ochiai N, Kishida S, Kuniyoshi , Nakamura J, Aoki Y, Ishikawa T, Miyagi M, Kamoda H, Suzuki M, Takaso M, Toyone T, Kubota G, Sakuma Y, Oikawa Y, Inage K, Sainoh T, Takahashi

STUDY DESIGN: Prospective study of changes in intervertebral disc degeneration after injection of bupivacaine. PURPOSE: To examine whether injection of bupivacaine into human intervertebral discs accelerates their degeneration. OVERVIEW OF LITERATURE: Bupivacaine...
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Interspinous Ligament Lidocaine and Steroid Injections for the Management of Baastrup's Disease: A Case Series

Okada K, Ohtori S, Inoue G, Orita S, Eguchi Y, Nakamura J, Aoki Y, Ishikawa T, Miyagi M, Kamoda H, Suzuki M, Kubota G, Sakuma Y, Oikawa Y, Inage K, Sainoh T, Toyone T, Yamauchi K, Takahashi

STUDY DESIGN: Prospective study. PURPOSE: To examine the long-term effects of interspinous ligament injections of local anesthetics and steroids for the treatment of Baastrup's diseases. OVERVIEW OF LITERATURE: Baastrup's disease is associated...
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Clinical Incidence of Sacroiliac Joint Arthritis and Pain after Sacropelvic Fixation for Spinal Deformity

Ohtori S, Sainoh T, Takaso M, Inoue G, Orita S, Eguchi Y, Nakamura J, Aoki Y, Ishikawa T, Miyagi M, Arai G, Kamoda H, Suzuki M, Kubota G, Sakuma Y, Oikawa Y, Yamazaki M, Toyone T, Takahashi

PURPOSE: Sacroiliac fixation using iliac screws for highly unstable lumbar spine has been reported with an improved fusion rate and clinical results. On the other hand, there is a potential...
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Evaluating Spinal Canal Lesions Using Apparent Diffusion Coefficient Maps with Diffusion-Weighted Imaging

Kanamoto H, Norimoto M, Eguchi Y, Oikawa Y, Orita S, Inage K, Abe K, Inoue M, Kinoshita H, Umimura T, Matsumoto K, Masuda Y, Furuya T, Koda M, Aoki Y, Watanabe A, Takahashi K, Ohtori S

Study Design: Observational study. Purpose: To evaluate healthy volunteers and patients with spinal canal lesions using apparent diffusion coefficient (ADC) maps with diffusion-weighted imaging. Overview of Literature: Decompression surgery for lumbar spinal...
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Injection of Bupivacaine into Disc Space to Detect Painful Nonunion after Anterior Lumbar Interbody Fusion (ALIF) Surgery in Patients with Discogenic Low Back Pain

Kimura S, Ohtori S, Orita S, Inoue G, Eguchi Y, Takaso M, Ochiai N, Kuniyoshi , Aoki Y, Ishikawa T, Miyagi M, Kamoda H, Suzuki M, Sakuma Y, Kubota G, Oikawa Y, Inage K, Sainoh T, Yamauchi K, Toyone T, Nakamura J, Kishida S, Sato J, Takahashi

  • KMID: 2386481
  • Yonsei Med J.
  • 2014 Mar;55(2):487-492.
PURPOSE: Bupivacaine is commonly used for the treatment of back pain and the diagnosis of its origin. Nonunion is sometimes observed after spinal fusion surgery; however, whether the nonunion causes...
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Progressive Change in Joint Degeneration in Patients with Knee or Hip Osteoarthritis Treated with Fentanyl in a Randomized Trial

Fujii T, Takana K, Orita S, Inoue G, Ochiai N, Kuniyoshi , Aoki Y, Ishikawa T, Miyagi M, Kamoda H, Suzuki M, Sakuma Y, Kubota G, Oikawa Y, Inage K, Sainoh T, Sato J, Yamauchi K, Toyone T, Nakamura J, Kishida S, Takahashi , Ohtori S

PURPOSE: Opioids improve pain from knee and hip osteoarthritis (OA) and decrease the functional impairment of patients. However, there is a possibility that opioids induce analgesia and suppress the physiological...
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Increase of TRPV1-Immunoreactivity in Dorsal Root Ganglia Neurons Innervating the Femur in a Rat Model of Osteoporosis

Yoshino K, Suzuki M, Kawarai Y, Sakuma Y, Inoue G, Orita S, Yamauchi K, Aoki Y, Ishikawa T, Miyagi M, Kamoda H, Kubota G, Oikawa Y, Inage K, Sainoh T, Sato J, Nakamura J, Toyone T, Takahashi , Ohtori S

PURPOSE: Transient receptor potential vanilloid 1 (TRPV1) is a ligand-gated nonselective cation channel, which can be activated by capsaicin and other noxious stimuli. Recently, an association between bone pain and...
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Transient Receptor Potential Vanilloid 1-Immunoreactive Innervation Increases in Fractured Rat Femur

Kawarai Y, Suzuki M, Yoshino K, Inoue G, Orita S, Yamauchi K, Aoki Y, Ishikawa T, Miyagi M, Kamoda H, Kubota G, Sakuma Y, Oikawa Y, Inage K, Sainoh T, Sato J, Nakamura J, Takaso M, Toyone T, Takahashi , Ohtori S

PURPOSE: Pain from vertebral or femoral neck fractures is a particularly important problem in clinical orthopaedics. Transient receptor potential vanilloid 1 (TRPV1) is a ligand-gated nonselective cation channel, and there...
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PainVision Apparatus Is Effective for Assessing Low Back Pain

Ohtori S, Kawaguchi , Takebayashi T, Orita S, Inoue G, Yamauchi K, Aoki Y, Nakamura J, Ishikawa T, Miyagi M, Kamoda H, Suzuki M, Kubota G, Sakuma Y, Oikawa Y, Inage K, Sainoh T, Sato J, Takahashi , Konno S

STUDY DESIGN: Case series. PURPOSE: To determine the utility of "PainVision" apparatus for the assessment of low back pain. OVERVIEW OF LITERATURE: A newly developed device, the PainVision PS-2100 (Nipro, Osaka, Japan),...
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Genetic Characterization of Clinical Acanthamoeba Isolates from Japan using Nuclear and Mitochondrial Small Subunit Ribosomal RNA

Rahman MM, Yagita K, Kobayashi , Oikawa Y, Hussein AI, Matsumura , Tokoro M

Because of an increased number of Acanthamoeba keratitis (AK) along with associated disease burdens, medical professionals have become more aware of this pathogen in recent years. In this study, by...
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The Time Course Changes in Bone Metabolic Markers after Administering the Anti-Receptor Activator of Nuclear Factor-Kappa B Ligand Antibody and Drug Compliance among Patients with Osteoporosis

Inage K, Orita S, Yamauchi K, Sakuma Y, Kubota G, Oikawa Y, Sainoh T, Sato J, Fujimoto K, Shiga Y, Takahashi , Ohtori S

STUDY DESIGN: Retrospective study. PURPOSE: We conducted a study to investigate the time course changes in bone metabolic markers after the administration of the anti-receptor activator of nuclear factor-kappa B ligand...
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Mini-Open Anterior Retroperitoneal Lumbar Interbody Fusion: Oblique Lateral Interbody Fusion for Lumbar Spinal Degeneration Disease

Ohtori S, Orita S, Yamauchi K, Eguchi Y, Ochiai N, Kishida S, Kuniyoshi , Aoki Y, Nakamura J, Ishikawa T, Miyagi M, Kamoda H, Suzuki M, Kubota G, Sakuma Y, Oikawa Y, Inage K, Sainoh T, Sato J, Fujimoto K, Shiga Y, Abe K, Toyone T, Inoue G, Takahashi

PURPOSE: Surgery for lumbar spinal degeneration disease is widely performed. While posterior decompression and fusion are popular, anterior lumbar interbody fusion (ALIF) is also used for treatment. Extreme lateral interbody...
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Up-Regulation of Pain Behavior and Glial Activity in the Spinal Cord after Compression and Application of Nucleus Pulposus onto the Sciatic Nerve in Rats

Norimoto M, Sakuma Y, Suzuki M, Orita S, Yamauchi K, Inoue G, Aoki Y, Ishikawa T, Miyagi M, Kamoda H, Kubota G, Oikawa Y, Inage K, Sainoh T, Sato J, Nakamura J, Toyone T, Takahashi , Ohtori S

STUDY DESIGN: Experimental animal study. PURPOSE: To evaluate pain-related behavior and changes in glial activity in the spinal dorsal horn after combined sciatic nerve compression and nucleus pulposus (NP) application in...
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Efficacy of Combination of Meloxicam and Pregabalin for Pain in Knee Osteoarthritis

Ohtori S, Inoue G, Orita S, Takaso M, Eguchi Y, Ochiai N, Kishida S, Kuniyoshi , Aoki Y, Ishikawa T, Miyagi M, Kamoda H, Suzkuki M, Nakamura J, Kubota G, Sakuma Y, Oikawa Y, Toyone T, Inage K, Sainoh T, Yamauchi K, Takahashi

PURPOSE: Osteoarthritic pain is largely considered to be inflammatory pain. Sensory nerve fibers innervating the knee have been shown to be significantly damaged in rat models of knee osteoarthritis (OA)...
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Discrimination between Lumbar Intraspinal Stenosis and Foraminal Stenosis using Diffusion Tensor Imaging Parameters: Preliminary Results

Eguchi Y, Ohtori S, Suzuki M, Oikawa Y, Yamanaka H, Tamai H, Kobayashi , Orita S, Yamauchi K, Suzuki M, Aoki Y, Watanabe A, Kanamoto H, Takahashi

STUDY DESIGN: Retrospective observational study. PURPOSE: To examine fractional anisotropy (FA) values and apparent diffusion coefficient (ADC) values of damaged nerves to discriminate between lumbar intraspinal stenosis (IS) and foraminal stenosis...
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Existence of a Neuropathic Pain Component in Patients with Osteoarthritis of the Knee

Ohtori S, Orita S, Yamashita , Ishikawa T, Ito T, Shigemura , Nishiyama , Konno S, Ohta H, Takaso M, Inoue G, Eguchi Y, Ochiai N, Kishida S, Kuniyoshi , Aoki Y, Arai G, Miyagi M, Kamoda H, Suzkuki M, Nakamura J, Furuya T, Kubota G, Sakuma Y, Oikawa Y, Suzuki M, Sasho T, Nakagawa K, Toyone T, Takahashi

PURPOSE: Pain from osteoarthritis (OA) is generally classified as nociceptive (inflammatory). Animal models of knee OA have shown that sensory nerve fibers innervating the knee are significantly damaged with destruction...
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