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The Intestinal Microbiota and Human Disease

Ko JS

Advances in sequencing technology and the development of metagenomics have opened up new ways to investigate the microorganisms inhabiting the human gut. The intestinal microbiota confer protection against pathogens, contribute...
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Effect of High Fat Diet on Insulin Resistance: Dietary Fat Versus Visceral Fat Mass

Park SY, Kim YW, Kim JY, Jang EC, Doh KO, Lee SK

The purpose of the present study was to determine whether chronic high-fat diet (HF) induces insulin resistance independently of obesity. We randomly divided 40 rats into two groups and fed...
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A Comparative Study of Youth Health Risk Behaviors by Region: Focused on Metropolitan Areas, Medium Sized and Small City Areas, and Rural Areas

Park E

PURPOSE: This study was done to compare health risk behavior prevalence for youth living in metropolitan, medium sized and small cities or rural area, in order to enhance understanding regional...
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Change in activity of the sympathetic nervous system in diet-induced obese rats

Park SY, Lee YJ, Kim YW, Kim HJ, Doh KO, Lee MK, Kim JY, Lee SK

We investigated the change in activity of the sympathetic nervous system (SNS) in high-sucrose diet (HSD)-induced obese rats compared with controls. Power spectral analyses of R-R interval variability were performed...
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Effects of Body Composition, Leptin, and Adiponectin on Bone Mineral Density in Prepubertal Girls

Rhie YJ, Lee KH, Chung SC, Kim HS, Kim DH

Body weight is positively associated with bone mineral density but the relationship between obesity and bone mineral density is unclear. Leptin and adiponectin are potential independent contributors to bone mineral...
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The relationship between plasma leptin and nutritional status in chronic hemodialysis patients

Koo JR, Pak KY, Kim KH, Chun RW, Kim HJ, Chae DW, Choi MG, Noh JW

Leptin serves an important role in suppressing appetite in mice and is known to be elevated in chronic renal failure (CRF) patients. But clinical significance of leptin as an appetite-reducing...
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Prognostic Impact of Changes in Adipose Tissue Areas after Colectomy in Colorectal Cancer Patients

Choe EK, Park KJ, Ryoo SB, Moon SH, Oh HK, Han EC

There have been few studies assessing the changes in the body components of patients after colectomy in colorectal cancer (CRC). The purpose of this study was to verify the trends...
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Antiobesity activity of a sphingosine 1-phosphate analogue FTY720 observed in adipocytes and obese mouse model

Moon MH, Jeong JK, Lee JH, Park YG, Lee YJ, Seol JW, Park SY

  • KMID: 1506224
  • Exp Mol Med.
  • 2012 Oct;44(10):603-614.
Higher levels of body fat are associated with an increased risk for development numerous adverse health conditions. FTY720 is an immune modulator and a synthetic analogue of sphingosine 1-phosphate (S1P),...
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Heart Rate Variability and Metabolic Syndrome in Hospitalized Patients with Schizophrenia

Lee K, Park J, Choi J, Park CG

PURPOSE: Reduced heart rate variability significantly increases cardiovascular mortality. Metabolic syndrome increases the cardiac autonomic dysfunction. Recently, increasing cardiovascular mortality has been reported in patients with schizophrenia. This study was...
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