- The Potential Role of Nitric Oxide in Halting Cancer Progression Through Chemoprevention
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Vahora H, Khan MA, Alalami U, Hussain A
- KMID: 2161517
- J Cancer Prev.
- 2016 Mar;21(1):1-12.
- doi: 10.15430/JCP.2016.21.1.1
Nitric oxide (NO) in general plays a beneficial physiological role as a vasorelaxant and the role of NO is decided by its concentration present in physiological environments. NO either facilitates... -
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- Immunohistochemical Expression of Placental Nitric Oxide Synthase in Preeclampsia and Normal Pregnancy
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Kim JI, Yoon SD, Kim DM
- KMID: 2261207
- Korean J Obstet Gynecol.
- 1998 Dec;41(12):2957-2961.
OBJECTIVE: Our purpose was to compare the expression of endothelial nitric oxide synthase in the placenta and umbilical cord of preeclamptic placenta with that of the normotensive placenta. METHOD: We... -
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- Genetic Polymorphism of Endothelial Nitric Oxide Synthase in Korean Schizophrenic Patients
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Choi MS, Chung SK, Cho GH, Kim DS, Hwang IK
- KMID: 2340942
- J Korean Neuropsychiatr Assoc.
- 2004 Jan;43(1):18-22.
OBJECTIVES: Although genotype of endothelial nitric oxide synthase has been investigated in many neuropsychiatric disorders, results were controversial and even contradictory. The purpose of this study was to investigate the... -
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- Effect of Valproic Acid on Nitric Oxide and Nitric Oxide Synthase in Trabecular Meshwork Cell
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Son MS, Park CH, Kim JW
- KMID: 2413817
- J Korean Ophthalmol Soc.
- 2018 Jun;59(6):543-548.
- doi: 10.3341/jkos.2018.59.6.543
PURPOSE: To investigate the effects of valproic acid on the production of nitric oxide (NO) and expression of endothelial nitric oxide synthase (eNOS) in cultured human trabecular meshwork cells (HTMC). METHODS:... -
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- Role of angiotensin II and nitric oxide in the rat paraventricular nucleus
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Yang EK
- KMID: 1606837
- Korean J Physiol Pharmacol.
- 2001 Feb;5(1):41-46.
To investigate the mutual relationship between angiotensin II (Ang II) and nitric oxide (NO) in paraventricular nucleus (PVN), Ang II receptor type Ia (AT1A), type Ib (AT1B), endothelial constitutive nitric oxide synthase (ecNOS),... -
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- Expression of nitric oxide synthase isoforms in the porcine ovary during follicular development
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Kim H, Moon C, Ahn M, Lee Y, Kim H, Kim S, Ha T, Jee Y, Shin T
- KMID: 1114849
- J Vet Sci.
- 2005 Jun;6(2):97-101.
The expression of nitric oxide synthase (NOS) isoforms in the ovaries of pigs was examined to study the involvement of nitric oxide, a product of NOS activity, in the function... -
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- The Effect of Estrogen on Expression of Neuronal and Endothelial Nitric Oxide Synthase and on Histologic Composition in Rat Bladder and Urethra
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Park SW, Lee JZ
- KMID: 2311985
- Korean J Urol.
- 2008 Jun;49(6):533-539.
PURPOSE: We investigated the effects of estrogen on the expression of neuronal nitric oxide synthase(nNOS) and on endothelial nitric oxide synthase(eNOS), and furthermore elucidated its effect on the histologic composition... -
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- Expression of Nitric Oxide Synthase(NOS) in Rat Bladders Subjected to Short-term Partial Outlet Obstruction
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Ihm DH, Chung HC, Song JM
- KMID: 2311966
- Korean J Urol.
- 2008 Jul;49(7):622-626.
PURPOSE: Nitric oxide synthase(NOS) is an important enzyme in the production of nitric oxide(NO). The constitutive type(cNOS) is expressed in the normal physiologic state, and the inducible type(iNOS) in expressed... -
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- Impaired endothelium-dependent relaxation is mediated by reduced production of nitric oxide in the streptozotocin-induced diabetic rats
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Park KS, Kim CS, Kang SW, Park JB, Kim KJ, Chang SJ, Jeon BH
- KMID: 1580813
- Korean J Physiol Pharmacol.
- 2000 Jun;4(3):263-270.
To evaluate the involvement of nitric oxide production on the endothelium-dependent relaxation in diabetes, we have measured vascular and endothelial function and nitric oxide concentration, and the expression level of... -
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- Immunohistochemical Localization of Endothelial Nitric Oxide Synthase in Normotensive and Preeclamptic Placentas
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Shin MS, Kim BH, Lee PY, Lee IS, Kim A, Huh JR, Mok JE
- KMID: 2269597
- Korean J Obstet Gynecol.
- 1999 May;42(5):968-974.
OBJECTIVE: Endothelial isoform of nitric oxide synthase[eNOS] regulates the vascular resistance by producing nitric oxide[NO], endothelium-derived relaxing factor. The purpose of this study was to compare the expression of eNOS... -
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- The dependence of nitric oxide synthase inhibition caused by cigarette smoking extract on the cellular aging of bovine aortic endothelial cells
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Le V, Kim YH, Min J
- KMID: 2380103
- Environ Health Toxicol.
- 2014 ;29(1):e2014010.
- doi: 10.5620/eht.e2014010
OBJECTIVES: Cigarette smoking had been recorded as the main cause of impaired endothelium- dependent vasodilation in smokers by reducing nitric oxide (NO), a production of endothelial nitric oxide synthase (eNOS).... -
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- Correlative Changes of Endothelial Nitric Oxide Synthase and Choline Acetyltransferase in the Hippocampus after Exercise
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Cho YK, Zi J, Choe GS, Kang HM, Kim J, Ahn H, Park C
- KMID: 2092941
- Korean J Anat.
- 2008 Sep;41(3):185-192.
We found that the expression and activity of endothelial nitric oxide synthase (eNOS) is increased in the hippocampus during exercise (Moon et al., 2006). However, the upstream regulatory factor on... -
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- The expression of endothelial nitric oxide synthase in the uterus
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Sou HJ, Kim JW, Kim SR, Yi SY
- KMID: 2273800
- Korean J Obstet Gynecol.
- 2009 Nov;52(11):1144-1151.
OBJECTIVE: Nitric oxide has a short half-life and is easily oxidized by nitrite, we can indirectly find out its activity by measuring the nitric oxide synthase in cells. The purpose... -
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- Endothelial Dysfunction-Its Molecular Mechanism and Potential Implication in Therapy
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Kim CH
- KMID: 1895023
- Korean Circ J.
- 2006 Sep;36(9):609-611.
- doi: 10.4070/kcj.2006.36.9.609
Endothelial dysfunction is known to be early stage of atherosclerosis and its presence leads to poor prognosis. Recently many basic researchs were done to elucidate the basic mechanism related to... -
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- p66shc Adaptor Protein Suppresses the Activation of Endothelial Nitric Oxide Synthase in Mouse Embryonic Fibroblasts
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Lee SK, Kim YS, Kim CS, Son SJ, Yoo DG, Lee KH, Lee SD, Park JB, Jeon BH
- KMID: 2285327
- Korean J Physiol Pharmacol.
- 2006 Jun;10(3):155-159.
Among the Shc proteins, p66shc is known to be related to oxidative stress responses and regulation of the production of reactive oxygen species (ROS). The present study was undertaken to... -
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- Effect of Rho Kinase Inhibitor on the Production of Nitric Oxide in Trabecular Meshwork Cells
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Kim JW, Kim KH, Hwang SJ
- KMID: 2212801
- J Korean Ophthalmol Soc.
- 2016 Apr;57(4):650-656.
- doi: 10.3341/jkos.2016.57.4.650
PURPOSE: To investigate the effects of Rho kinase (ROCK) inhibitor on the production of nitric oxide (NO) and expression of endothelial nitric oxide synthase (eNOS) in cultured human trabecular meshwork... -
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- Blood Pressure Variability and Vascular Dysfunction in Essential Hypertension
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Okumura K, Cheng XW
- KMID: 2330956
- J Korean Soc Hypertens.
- 2012 Sep;18(3):75-87.
There are several aspects of blood pressure. Clinically, how to best assess blood pressure average and variability is still a matter of the ongoing debate. Besides office blood pressure, we... -
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- The Effects of Estrogen on Neuronal Nitric Oxide Synthase Expression, Endothelial Nitric Oxide Synthase Expression and Vascular Endothelial Growth Factor Expression and on the Histologic Composition of Rat Uterus and Vagina
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Park SW, Lee YJ, Lee JZ
- KMID: 2294216
- Korean J Urol.
- 2006 Jan;47(1):55-63.
- doi: 10.4111/kju.2006.47.1.55
PURPOSE: As suggested by many investigators, the cause of age-related female sexual dysfunction is the decline of serum estrogen. We investigated the effects of estrogen on the nitric oxide synthase... -
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- Dexmedetomidine inhibits vasoconstriction via activation of endothelial nitric oxide synthase
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Nong L, Ma J, Zhang G, Deng C, Mao S, Li H, Cui J
- KMID: 2350500
- Korean J Physiol Pharmacol.
- 2016 Sep;20(5):441-447.
- doi: 10.4196/kjpp.2016.20.5.441
Despite the complex vascular effects of dexmedetomidine (DEX), its actions on human pulmonary resistance arteries remain unknown. The present study tested the hypothesis that DEX inhibits vascular tension in human... -
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- Tat-Mediated p66shc Transduction Decreased Phosphorylation of Endothelial Nitric Oxide Synthase in Endothelial Cells
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Lee SK, Lee JY, Joo HK, Cho EJ, Kim CS, Lee SD, Park JB, Jeon BH
- KMID: 1768014
- Korean J Physiol Pharmacol.
- 2012 Jun;16(3):199-204.
- doi: 10.4196/kjpp.2012.16.3.199
We evaluated the role of Tat-mediated p66shc transduction on the activation of endothelial nitric oxide synthase in cultured mouse endothelial cells. To construct the Tat-p66shc fusion protein, human full length... -
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