- Epstein-Barr Virus and p16INK4A Methylation in Squamous Cell Carcinoma and Precancerous Lesions of the Cervix Uteri
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Kim NR, Lin Z, Kim KR, Cho HY, Kim I
- KMID: 1712746
- J Korean Med Sci.
- 2005 Aug;20(4):636-642.
- doi: 10.3346/jkms.2005.20.4.636
Methylation of p16 is an important mechanism in cervical carcinogenesis. However, the relationship between cervical squamous cell carcinoma (SCC) and Epstein-Barr virus (EBV) remains controversial. Here, we explored whether EBV... -
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- Risk Factors for Metachronous Gastric Neoplasms in Patients Who Underwent Endoscopic Resection of a Gastric Neoplasm
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Yoon H, Kim N, Shin CM, Lee HS, Kim BK, Kang GH, Kim JM, Kim JS, Lee DH, Jung HC
- KMID: 2363967
- Gut Liver.
- 2016 Mar;10(2):228-236.
- doi: 10.5009/gnl14472
BACKGROUND/AIMS: To identify the risk factors for metachronous gastric neoplasms in patients who underwent an endoscopic resection of a gastric neoplasm. METHODS: We prospectively collected clinicopathologic data and measured the methylation... -
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- A Case of Multiple Endocrine Neoplasia Type 1 Combined with Papillary Thyroid Carcinoma
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Kim HJ, Park JS, Kim CS, Kang ES, Cha BS, Lim SK, Kim KR, Lee HC, Ahn CW
- KMID: 724269
- Yonsei Med J.
- 2008 Jun;49(3):503-506.
- doi: 10.3349/ymj.2008.49.3.503
This is the first report of papillary thyroid carcinoma combined with multiple endocrine neoplasia type 1 (MEN1) in Korea. MEN1 is a hereditary disease comprising neoplastic disorders such as pituitary,... -
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- Genetic Alterations in Primary Gastric Carcinomas Correlated with Clinicopathological Variables by Array Comparative Genomic Hybridization
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Kang JU, Kang JJ, Kwon KC, Park JW, Jeong TE, Noh SM, Koo SH
- KMID: 2157817
- J Korean Med Sci.
- 2006 Aug;21(4):656-665.
- doi: 10.3346/jkms.2006.21.4.656
Genetic alterations have been recognized as an important event in the carcinogenesis of gastric cancer (GC). We conducted high resolution bacterial artificial chromosome array-comparative genomic hybridization, to elucidate in more... -
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- Site-specific Colorectal Cancer; How Is It Different?
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Kim HS
- KMID: 1775768
- Korean J Gastroenterol.
- 2013 Feb;61(2):63-70.
- doi: 10.4166/kjg.2013.61.2.63
One of the most critical characteristics of colorectal cancer (CRC) is the difference between proximal (right-sided colon cancer, RCC) and distal (left-sided colon cancer, LCC) disease. The recent CRC studies... -
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- Update on rare epithelial ovarian cancers: based on the Rare Ovarian Tumors Young Investigator Conference
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Jang JY, Yanaihara , Pujade-Lauraine E, Mikami Y, Oda K, Bookman M, Ledermann , Shimada M, Kiyokawa T, Kim BG, Matsumura , Kaku T, Kuroda T, Nagayoshi , Kawabata A, Iida Y, Kim JW, Quinn M, Okamoto A
- KMID: 2413437
- J Gynecol Oncol.
- 2017 Jul;28(4):e54.
- doi: 10.3802/jgo.2017.28.e54
There has been significant progress in the understanding of the pathology and molecular biology of rare ovarian cancers, which has helped both diagnosis and treatment. This paper provides an update... -
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- Mitochondrial DNA Aberrations and Pathophysiological Implications in Hematopoietic Diseases, Chronic Inflammatory Diseases, and Cancers
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Kim HR, Won SJ, Fabian C, Kang MG, Szardenings M, Shin MG
- KMID: 2363141
- Ann Lab Med.
- 2015 Jan;35(1):1-14.
- doi: 10.3343/alm.2015.35.1.1
Mitochondria are important intracellular organelles that produce energy for cellular development, differentiation, and growth. Mitochondrial DNA (mtDNA) presents a 10- to 20-fold higher susceptibility to genetic mutations owing to the... -
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- Impaired phosphorylation and mis-localization of Bub1 and BubR1 are responsible for the defective mitotic checkpoint function in Brca2-mutant thymic lymphomas
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Lee H
- KMID: 1093618
- Exp Mol Med.
- 2003 Oct;35(5):448-453.
Breast cancer susceptibility gene, BRCA2, is a tumor suppressor and individuals who inherit one defected copy of BRCA2 allele experience early onset breast cancer or ovarian cancer accompanied by the... -
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- P70S6K and Elf4E Dual Inhibition Is Essential to Control Bladder Tumor Growth and Progression in Orthotopic Mouse Non-muscle Invasive Bladder Tumor Model
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Chi BH, Kim SJ, Seo HK, Seo HH, Lee SJ, Kwon JK, Lee TJ, Chang IH
- KMID: 2133310
- J Korean Med Sci.
- 2015 Mar;30(3):308-316.
- doi: 10.3346/jkms.2015.30.3.308
We investigated how the dual inhibition of the molecular mechanism of the mammalian target of the rapamycin (mTOR) downstreams, P70S6 kinase (P70S6K) and eukaryotic initiation factor 4E (eIF4E), can lead... -
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- Association of Toll-Like Receptor 2 Polymorphisms with Papillary Thyroid Cancer and Clinicopathologic Features in a Korean Population
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Kim MK, Park SW, Kim SK, Park HJ, Eun YG, Kwon KH, Kim J
- KMID: 2157943
- J Korean Med Sci.
- 2012 Nov;27(11):1333-1338.
- doi: 10.3346/jkms.2012.27.11.1333
Toll-like receptors (TLRs) single nucleotide polymorphisms (SNPs) were analyzed in patients with papillary thyroid cancer (PTC; n = 133) and their clinicopathologic features and age-matched controls (n = 321) using... -
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- Anthocyanin Induces Apoptosis of DU-145 Cells In Vitro and Inhibits Xenograft Growth of Prostate Cancer
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Ha US, Bae WJ, Kim SJ, Yoon BI, Hong SH, Lee JY, Hwang TK, Hwang SY, Wang Z, Kim SW
- KMID: 2352784
- Yonsei Med J.
- 2015 Jan;56(1):16-23.
- doi: 10.3349/ymj.2015.56.1.16
PURPOSE: To investigate the effects of anthocyanins extracted from black soybean, which have antioxidant activity, on apoptosis in vitro (in hormone refractory prostate cancer cells) and on tumor growth in... -
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