- Cancer cell metabolism: implications for therapeutic targets
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Jang M, Kim SS, Lee J
- KMID: 2154264
- Exp Mol Med.
- 2013 Oct;45(10):e45.
Cancer cell metabolism is characterized by an enhanced uptake and utilization of glucose, a phenomenon known as the Warburg effect. The persistent activation of aerobic glycolysis in cancer cells can... -
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- Effect of curcumin on the interaction between androgen receptor and Wnt/beta-catenin in LNCaP xenografts
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Hong JH, Lee G, Choi HY
- KMID: 2344105
- Korean J Urol.
- 2015 Sep;56(9):656-665.
- doi: 10.4111/kju.2015.56.9.656
PURPOSE: Curcumin is a nontoxic, chemopreventive agent possessing multifaceted functions. Our previous study showed that curcumin inhibits androgen receptor (AR) through modulation of Wnt/beta-catenin signaling in LNCaP cells. Therefore, we... -
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- Inhibition of autophagy protein LC3A as a therapeutic target in ovarian clear cell carcinomas
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Miyamoto M, Takano M, Aoyama T, Soyama H, Yoshikawa , Tsuda H, Furuya K
- KMID: 2413444
- J Gynecol Oncol.
- 2017 May;28(3):e33.
- doi: 10.3802/jgo.2017.28.e33
OBJECTIVE: Ovarian clear cell carcinoma (CCC) is one of histological subtypes showing poor prognosis due to chemoresistance. The association of autophagy-related proteins and clinical implementation in CCC has not been... -
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- Pseudomonas aeruginosa Exotoxin A Reduces Chemoresistance of Oral Squamous Carcinoma Cell via Inhibition of Heat Shock Proteins 70 (HSP70)
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Park SR, Lee KD, Kim UK, Gil YG, Oh KS, Park BS, Kim GC
- KMID: 1071422
- Yonsei Med J.
- 2010 Sep;51(5):708-716.
- doi: 10.3349/ymj.2010.51.5.708
PURPOSE: Oral squamous carcinoma (OSCC) cells exhibit resistance to chemotherapeutic agent-mediated apoptosis in the late stage of malignancy. Increased levels of heat shock proteins 70 (HSP70) in cancer cells are... -
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- Pathophysiological Role of Hormones and Cytokines in Cancer Cachexia
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Kim HJ, Kim HJ, Yun J, Kim KH, Kim SH, Lee SC, Bae SB, Kim CK, Lee NS, Lee KT, Park SK, Won JH, Park HS, Hong DS
- KMID: 1120148
- J Korean Med Sci.
- 2012 Feb;27(2):128-134.
- doi: 10.3346/jkms.2012.27.2.128
We investigated the role of fasting hormones and pro-inflammatory cytokines in cancer patients. Hormones (ghrelin, adiponectin, and leptin) and cytokines (TNF-alpha, IFN-gamma, and IL-6) were measured by ELISA or RIA... -
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- Cellular uptake of magnetic nanoparticle is mediated through energydependent endocytosis in A549 cells
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Kim JS, Yoon TJ, Yu KN, Noh MS, Woo M, Kim BG, Lee KH, Sohn BH, Park SB, Lee JK, Cho MH
- KMID: 1089477
- J Vet Sci.
- 2006 Dec;7(4):321-326.
- doi: 10.4142/jvs.2006.7.4.321
Biocompatible silica-overcoated magnetic nanoparticles containing an organic fluorescence dye, rhodamine B isothiocyanate (RITC), within a silica shell [50 nm size, MNP@SiO2(RITC)s] were synthesized. For future application of the MNP@SiO2(RITC)s into... -
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- Usefulness of Carcinoembryonic Antigen for Monitoring Tumor Progression during Palliative Chemotherapy in Metastatic Colorectal Cancer
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Kim G, Jung EJ, Ryu CG, Hwang DY
- KMID: 1776926
- Yonsei Med J.
- 2013 Jan;54(1):116-122.
- doi: 10.3349/ymj.2013.54.1.116
PURPOSE: To evaluate the efficacy of carcinoembryonic antigen (CEA) measurement for monitoring tumor progression during palliative chemotherapy in metastatic colorectal cancer. MATERIALS AND METHODS: Forty-eight patients with initially unresectable metastatic colorectal... -
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- 14-3-3ζ Overexpression is Associated with Poor Prognosis in Ovarian Cancer
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Kim HJ, Sung SH, Kim CY, Bae MK, Cho MS, Kim YH, Kim SC, Ju W
- KMID: 2418848
- Yonsei Med J.
- 2018 Jan;59(1):51-56.
- doi: 10.3349/ymj.2018.59.1.51
PURPOSE: 14-3-3ζ regulates cell signaling, cell cycle progression, and apoptosis, and its overexpression is associated with disease recurrence and poor clinical outcomes in some solid tumors. However, its clinicopathological role... -
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