- Is It Possible to Predict Chemotherapy Response by the Gene Expression?
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Choi JH
- KMID: 1767512
- Korean J Gastroenterol.
- 2005 Jul;46(1):66-68.
No abstract available -
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- Association between excision repair cross-complementation group 1 polymorphism and clinical outcome of platinum-based chemotherapy in patients with epithelial ovarian cancer
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Kang S, Ju W, Kim JW, Park NH, Song YS, Kim SC, Park SY, Kang SB, Lee HP
- KMID: 1094158
- Exp Mol Med.
- 2006 Jun;38(3):320-324.
ERCC1 is a DNA repair gene and has been associated with resistance to DNA damaging agents. In this study we hypothesized that a polymorphism of ERCC1 Asn118Asn (C->T) might affect... -
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- Identification of Novel Methylation Markers in Hepatocellular Carcinoma using a Methylation Array
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Shin SH, Kim BH, Jang JJ, Suh KS, Kang GH
- KMID: 1714035
- J Korean Med Sci.
- 2010 Aug;25(8):1152-1159.
- doi: 10.3346/jkms.2010.25.8.1152
Promoter CpG island hypermethylation has become recognized as an important mechanism for inactivating tumor suppressor genes or tumor-related genes in human cancers of various tissues. Gene inactivation in association with... -
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- Rottlerin enhances IL-1beta-induced COX-2 expression through sustained p38 MAPK activation in MDA-MB-231 human breast cancer cells
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Park EJ, Kwon TK
- KMID: 1058704
- Exp Mol Med.
- 2011 Dec;43(12):669-675.
- doi: 10.3858/emm.2011.43.12.077
Cyclooxygenase-2 (COX-2) is an important enzyme in inflammation. In this study, we investigated the underlying molecular mechanism of the synergistic effect of rottlerin on interleukin1beta (IL-1beta)-induced COX-2 expression in MDA-MB-231... -
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- EGF Induced RET Inhibitor Resistance in CCDC6-RET Lung Cancer Cells
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Chang H, Sung JH, Moon SU, Kim HS, Kim JW, Lee JS
- KMID: 2374183
- Yonsei Med J.
- 2017 Jan;58(1):9-18.
- doi: 10.3349/ymj.2017.58.1.9
PURPOSE: Rearrangement of the proto-oncogene rearranged during transfection (RET) has been newly identified potential driver mutation in lung adenocarcinoma. Clinically available tyrosine kinase inhibitors (TKIs) target RET kinase activity, which... -
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- DNMT1 mediates chemosensitivity by reducing methylation of miRNA-20a promoter in glioma cells
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Zhou D, Wan Y, Xie D, Wang Y, Wei J, Yan Q, Lu P, Mo L, Xie J, Yang S, Qi X
- KMID: 2155436
- Exp Mol Med.
- 2015 Sep;47(9):e182.
- doi: 10.1038/emm.2015.57
Although methyltransferase has been recognized as a major element that governs the epigenetic regulation of the genome during temozolomide (TMZ) chemotherapy in glioblastoma multiforme (GBM) patients, its regulatory effect on... -
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- Association between Genetic Polymorphisms of CYP2D6 and Outcomes in Breast Cancer Patients with Tamoxifen Treatment
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Park HS, Choi JY, Lee MJ, Park S, Yeo CW, Lee SS, Shin JG, Park BW
- KMID: 1777838
- J Korean Med Sci.
- 2011 Aug;26(8):1007-1013.
- doi: 10.3346/jkms.2011.26.8.1007
The aim of the study was to evaluate the association between genetic polymorphisms of CYP2D6 and outcomes in breast cancer patients with tamoxifen treatment. We evaluated the CYP2D6 genetic polymorphisms... -
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