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Role of C-type Natriuretic Peptide in Linear Growth

Chung WY

The natriuretic peptides are a family of three peptides, atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP) and C-type natriuretic peptide (CNP). CNP is produced in the growth plate and...
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Effect of atrial natriuretic peptide on the proliferation and activity of osteoblastic cells

Lee JR, Ko SY, Kim JK, Kim SW

  • KMID: 1917021
  • Korean J Physiol Pharmacol.
  • 2000 Aug;4(4):283-289.
Natriuretic peptides comprise a family of three structurally related peptides; atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), and C-type natriuretic peptide (CNP). The present study was performed to investigate the effect of...
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Bio-Molecular Markers for Cardiovascular Disease: Significance of Natriuretic Peptides and Adrenomedullin

Horio T, Kawano Y

There are many established and proposed bio-molecular markers for cardiovascular disease, including vasoactive substances, substances related to inflammation and oxidative stress, and substances involved in tissue structure and remodeling. Among...
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Upregulation of Renin-angiotensin, Endothelin and C-type Natriuretic Peptide in Rat Glomerulus with Bilateral Ureteral Obstruction

Bae EH, Kim SW

  • KMID: 1587476
  • Korean J Physiol Pharmacol.
  • 2006 Dec;10(6):343-347.
The present study was designed to investigate the effects renin-angiotensin-aldosterone system (RAAS), endothelin (ET) and local natriuretic peptide (NP) system for glomerulopathy induced in the experimental bilateral ureteral obstructive rats....
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Abnormal Relaxation Responses to C-type Natriuretic Peptide in Aorta and Pulmonary Artery of Rats with Congestive Heart Failure

Kim CH, Kim KI, Cho YS, Zo JH, Oh BH, Lee MM, Park YB, Choi YS, Lee YW

BACKGROUND: C-type natriuretic peptide (CNP), secreted from endothelial cells, dilates the vessel and increases the renal excretion of sodium and water. Plasma CNP level is not elevated in patients with...
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C-Type Natriuretic Peptide/Natriuretic Peptide Receptor 2 Is Involved in Cell Proliferation and Testosterone Production in Mouse Leydig Cells

Yang L, Lei L, Zhao Q, Gong Y, Guan G, Huang S

PURPOSE: This study investigated the role of natriuretic peptide receptor 2 (NPR2) on cell proliferation and testosterone secretion in mouse Leydig cells. MATERIALS AND METHODS: Mouse testis of different postnatal stages...
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Expression of C-type Natriuretic Peptide and Natriuretic Peptide Receptors in the Mouse Submandibular Glands Following Embryonic Development, Postnatal Differentiation and Aging

Bok SM, Kim TH, Park KR, Cho ES

  • KMID: 1564369
  • Korean J Anat.
  • 2005 Aug;38(4):325-336.
C-type natriuretic peptide (CNP), a member of natriuretic peptide family, is mainly synthesized in the endothelium and central nervous system. But CNP is also involved in the growth and differentiation...
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Effects of Phosphodiesterase 5 Inhibition with Sildenafil on Atrial Contractile and Secretory Function

Quan HX, Kim SY, Jin XS, Park JK, Kim SZ, Cho KW

  • KMID: 2285326
  • Korean J Physiol Pharmacol.
  • 2006 Jun;10(3):149-154.
Selective inhibition of phosphodiesterase (PDE) 5 opened a new therapeutic approach for cardiovascular disorders. Therefore, the effect of PDE5 inhibition on the cardiac function should thoroughly be defined. The purpose...
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C-Type Natriuretic Peptide as a Surrogate Marker in Variant Angina Pectoris

Lee DH, Youn HJ, Choi YS, Lee JM, Park CS, Jung HO, Jeon HK, Lee MY

BACKGROUND AND OBJECTIVES: The purpose of this study was to assess the value of C-type natriuretic peptide (CNP) as a surrogate marker for detection of coronary artery spasm in variant...
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