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Metabolic dysfunction-associated fatty liver disease is a ubiquitous latent cofactor in viral- and alcoholic-related hepatocellular carcinoma: Editorial on “Global prevalence of metabolic dysfunction-associated fatty liver disease-related hepatocellular carcinoma: A systematic review and meta-analysis”

Nakamura T, Nakano M, Tsutsumi T, Amano K, Kawaguchi T

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Recurrent Infective Endocarditis Following Transcatheter Edge-to-Edge Mitral Valve Repair with MitraClip System

Kadoya Y, Zen K, Fukai K, Matsubayashi K, Yamano M, Yamano T, Nakamura T, Matoba S

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The Current Strategy for Managing Pancreatic Neuroendocrine Tumors in Multiple Endocrine Neoplasia Type 1

Niina Y, Fujimori N, Nakamura T, Igarashi H, Oono T, Nakamura K, Kato M, Jensen RT, Ito T, Takayanagi R

  • KMID: 2053489
  • Gut Liver.
  • 2012 Jul;6(3):287-294.
Multiple endocrine neoplasia type 1 (MEN1) is an inherited autosomal dominant disease presenting with pancreatic neuroendocrine tumors (pNETs), parathyroid tumors, or pituitary tumors. Using the PubMed database, we reviewed the...
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Study of the cartilage matrix production-promoting effect of chicken leg extract and identification of the active ingredient

Yamada H, Nakamura U, Nakamura T, Uchida Y, Yamatsu A, Kim M

BACKGROUND/OBJECTIVES: Osteoarthritis (OA) is a major public health issue in Japan and other countries, and foods that prevent or treat OA are in strong demand. Proteins and peptides in chicken...
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Exposure to paraben and triclosan and allergic diseases in Tokyo: A pilot cross-sectional study

Mitsui-Iwama M, Yamamoto-Hanada K, Fukutomi Y, Hirota R, Muto G, Nakamura T, Yoshikawa , Nakamura H, Mikami M, Morioka I, Ohya Y

BACKGROUND: Previous studies have reported that exposure to paraben (Pb) and triclosan (TCS) is associated with allergies. However, Pb and TCS exposure in the Japanese population is not fully understood. OBJECTIVES:...
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Angiopoietin-Like Protein 2 Induces Synovial Inflammation in the Facet Joint Leading to Degenerative Changes via Interleukin-6 Secretion

Sugimoto K, Nakamura T, Tokunaga T, Uehara Y, Okada T, Taniwaki T, Fujimoto T, Oike Y, Nakamura E

STUDY DESIGN: Experimental human study. PURPOSE: To determine whether angiopoietin-like protein 2 (ANGPTL2) is highly expressed in the hyperplastic facet joint (FJ) synovium and whether it activates interleukin-6 (IL-6) secretion in...
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Oncoplastic Technique Combining an Adipofascial Flap with an Extended Glandular Flap for the Breast-Conserving Reconstruction of Small Dense Breasts

Ogawa T, Hanamura N, Yamashita , Kimura H, Ito M, Nakamura T, Kashikura , Nohara Y, Noro A

We introduce a method combining two oncoplastic techniques for breast-conserving reconstruction. The procedure is as follows: first, an extended glandular flap is made by undermining the breast from both the...
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Abdominal Advancement Flap as Oncoplastic Breast Conservation: Report of Seven Cases and Their Cosmetic Results

Ogawa T, Hanamura N, Yamashita , Ito M, Kimura H, Nakamura T, Kashikura , Nohara Y, Noro A

An abdominal advancement flap (AAF) is a flap that pulls the elevated abdominal skin up and creates the shape of the inferior portion of the breast by making a neo-inframammary...
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Phase 2 single-arm study on the efficacy and safety of niraparib in Japanese patients with heavily pretreated, homologous recombination-deficient ovarian cancer

Okamoto A, Kondo E, Nakamura T, Yanagida S, Hamanishi J, Harano K, Hasegawa K, Hirasawa T, Hori K, Komiyama S, Matsuura M, Nakai H, Nakamura H, Sakata J, Tabata T, Takehara K, Takekuma M, Yokoyama Y, Kase Y, Sumino S, Soeda J, Suri A, Aoki D, Sugiyama T

Objective: To evaluate the efficacy and safety of niraparib in Japanese women with heavily pretreated ovarian cancer. Methods: This Phase 2 open-label, single-arm study enrolled Japanese women with homologous recombination deficiency-positive...
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Stand-Alone Anterior Cervical Discectomy and Fusion Using an Additive Manufactured Individualized Bioactive Porous Titanium Implant without Bone Graft: Results of a Prospective Clinical Trial

Fujibayashi S, Takemoto M, Nakamura T, Matsushita T, Kokubo T, Sasaki K, Mori S, Matsuda S

The purpose of this study was to introduce our patient-specific bioactive porous titanium implant manufactured using selective laser melting (SLM) and to establish the efficacy and safety of the implant...
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Iatrogenic Lumbar Vertebral Fracture during Osteosynthesis for a Trochanteric Fracture of the Femur in Diffuse Idiopathic Skeletal Hyperostosis

Sasagawa T, Murakami H, Maruhashi , Segawa T, Yamamoto D, Shimizu S, Morita Y, Nakamura T

Vertebral fractures occur with only slight trauma in patients with diffuse idiopathic skeletal hyperostosis (DISH). However, a lumbar vertebra fracture, due to an intraoperative body position has not been previously...
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Development of New Organ Preservation Solutions in Kyoto University

Chen F, Nakamura T, Wada H

Although lung transplantation (LTx) has been established as a therapeutic approach for end-stage respiratory failure, several problems remain to be solved. In addition to the serious problem of donor shortage,...
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Delphi Method Consensus-Based Identification of Primary Trauma Care Skills Required for General Surgeons in Japan

Hirose K, Murakami S, Kurashima Y, Sato N, Poudel S, Tanaka K, Matsui A, Nakanishi Y, Asano T, Noji T, Ebihara Y, Nakamura T, Tsuchikawa T, Shichinohe T, Okada K, Yokota I, Hasegawa N, Hirano S

Purpose: General surgeons at regional hospitals should have the primary trauma care skills necessary to treat critically ill trauma patients to withstand transfer. This study was conducted to identify a...
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Polypharmacy is a risk factor for disease flare in adult patients with ulcerative colitis: a retrospective cohort study

Wang J, Nakamura T, Tuskey AG, Behm BW

BACKGROUND/AIMS: Polypharmacy is a common clinical problem with chronic diseases that can be associated with adverse patient outcomes. The present study aimed to determine the prevalence and patient-specific characteristics associated...
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Associated Factors for Lumbar Degenerative Spondylolisthesis in Japanese Patients with Osteoarthritis of the Hip: A Radiographic Study

Sasagawa T, Nakamura T

STUDY DESIGN: Retrospective study. PURPOSE: To determine the presence and frequency of factors for degenerative spondylolisthesis (DS) in patients with hip osteoarthritis (OA). OVERVIEW OF LITERATURE: OA of the hip joint (hip...
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Cosmetic Evaluation Methods Adapted to Asian Patients after Breast-Conserving Surgery and Examination of the Necessarily Elements for Cosmetic Evaluation

Nohara Y, Hanamura N, Zaha H, Kimura H, Kashikura , Nakamura T, Noro A, Imai N, Shibusawa , Ogawa T

PURPOSE: Although various strategies have been reported, there are no defined criteria for cosmetic evaluation methods after breast-conserving surgery (BCS). Since Asians tend to have smaller breasts, indistinct inframammary folds,...
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Multicenter Prospective Study of Lateral Lumbar Interbody Fusions Using Bioactive Porous Titanium Spacers without Bone Grafts

Fujibayashi S, Takemoto M, Ishii K, Funao H, Isogai N, Otsuki B, Shimizu T, Nakamura T, Matsuda S

Study Design: Prospective multicenter clinical study. Purpose: To evaluate the efficacy of bioactive surface treatment for porous titanium spacers without bone graft for lateral lumbar interbody fusion (LLIF) through clinical and...
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Clinical Outcomes of Biliary Drainage during a Neoadjuvant Therapy for Pancreatic Cancer: Metal versus Plastic Stents

Kuwatani M, Nakamura T, Hayashi T, Kimura Y, Ono M, Motoya M, Imai K, Yamakita K, Goto T, Takahashi K, Maguchi H, Hirano S, Hokkaido Pancreatic Cancer Study Group (HOPS)

Neoadjuvant chemotherapy/neoadjuvant chemoradiotherapy (NAC/NACRT) can be performed in patients with pancreatic cancer to improve survival. We aimed to clarify the clinical outcomes of biliary drainage with a metal stent (MS)...
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Endoscopic Ultrasound-Guided Tissue Acquisition by 22-Gauge Franseen and Standard Needles for Solid Pancreatic Lesions

Ishigaki K, Nakai Y, Oyama H, Kanai S, Suzuki T, Nakamura T, Sato T, Hakuta R, Saito K, Saito T, Takahara N, Hamada T, Mizuno S, Kogure H, Tada M, Isayama H, Koike K

Background/Aims: Recently, a three-plane symmetric nee- dle with Franseen geometry was developed for endoscopic ultrasound-guided fine needle biopsy (EUS-FNB). In this ret-rospective study, tissue acquisition per pass was compared between 22-gauge...
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Clinical and Imaging Features of Multiple System Atrophy: Challenges for an Early and Clinically Definitive Diagnosis

Watanabe H, Riku Y, Hara K, Kawabata K, Nakamura T, Ito M, Hirayama M, Yoshida M, Katsuno M, Sobue G

Multiple system atrophy (MSA) is an adult-onset, progressive neurodegenerative disorder. Patients with MSA show various phenotypes during the course of their illness, including parkinsonism, cerebellar ataxia, autonomic failure, and pyramidal...
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