- Calcium Sensitization Mechanisms in Gastrointestinal Smooth Muscles
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Perrino BA
- KMID: 2203574
- J Neurogastroenterol Motil.
- 2016 Apr;22(2):213-225.
- doi: 10.5056/jnm15186
An increase in intracellular Ca2+ is the primary trigger of contraction of gastrointestinal (GI) smooth muscles. However, increasing the Ca2+ sensitivity of the myofilaments by elevating myosin light chain phosphorylation... -
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- Cardiac Hypertrophy in Transgenic Mice with Overexpressed Small-Subunit of Human Myosin Light Chain Phosphatase
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Bae SW, Lee WH, Kim CH, Park HK, Lee SC, Ko YH, Park SW, Arimura T, Kimura A, Park JE
- KMID: 2227250
- Korean Circ J.
- 2003 Dec;33(12):1165-1173.
- doi: 10.4070/kcj.2003.33.12.1165
BACKGROUND AND OBJECTIVES: Recent reports have demonstrated that perturbation of the balance between myo-sin light chain (MLC) phosphorylation and the dephosphorylation status is associated with the development of cardiac hypertrophy.... -
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- Flavone Attenuates Vascular Contractions by Inhibiting RhoA/Rho Kinase Pathway
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Baek I, Jeon SB, Song MJ, Yang E, Sohn UD, Kim IK
- KMID: 2071672
- Korean J Physiol Pharmacol.
- 2009 Jun;13(3):201-207.
- doi: 10.4196/kjpp.2009.13.3.201
Our previous study demonstrated that flavone inhibits vascular contractions by decreasing the phosphorylation levelof the myosin phosphatase target subunit (MYPT1). In the present study, we hypothesized that flavone attenuates vascular... -
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- Endothelium Independent Effect of Pelargonidin on Vasoconstriction in Rat Aorta
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Min YS, Yoon HJ, Je HD, Lee JH, Yoo SS, Shim HS, Lee HY, La HO, Sohn UD
- KMID: 2420388
- Biomol Ther.
- 2018 Jul;26(4):374-379.
- doi: 10.4062/biomolther.2017.197
In this study, we investigated the effects of pelargonidin, an anthocyanidin found in many fruits and vegetables, on endothelium-independent vascular contractility to determine the underlying mechanism of relaxation. Isometric contractions... -
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- Comparison of Improving Effects for Diabetic Erectile Dysfunction according to the Anti-Glycemic Agents: Phlorizin and Insulin
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Park J, Kwon O, Cho SY, Cho MC, Paick JS, Kim SW
- KMID: 2443236
- World J Mens Health.
- 2019 May;37(2):210-218.
- doi: 10.5534/wjmh.180057
PURPOSE: To compare the improving effects of diabetic erectile dysfunction with two anti-glycemic agents; phlorizin and insulin. MATERIALS AND METHODS: Sixty Sprague-Dawley rats were divided into four groups (n=15 in each... -
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- Lipid emulsion inhibits vasodilation induced by a toxic dose of bupivacaine by suppressing bupivacaine-induced PKC and CPI-17 dephosphorylation but has no effect on vasodilation induced by a toxic dose of mepivacaine
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Cho H, Ok SH, Kwon SC, Lee SH, Baik J, Kang S, Oh J, Sohn JT
- KMID: 2354215
- Korean J Pain.
- 2016 Oct;29(4):229-238.
- doi: 10.3344/kjp.2016.29.4.229
BACKGROUND: The goal of this in vitro study was to investigate the effect of lipid emulsion on vasodilation caused by toxic doses of bupivacaine and mepivacaine during contraction induced by... -
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- Is It Possible to Recover Erectile Function Spontaneously after Cavernous Nerve Injury? Time-Dependent Structural and Functional Changes in Corpus Cavernosum Following Cavernous Nerve Injury in Rats
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Kim TB, Cho MC, Paick JS, Kim SW
- KMID: 2298806
- Korean J Androl.
- 2012 Apr;30(1):31-39.
- doi: 10.5534/kja.2012.30.1.31
PURPOSE: There has been a scarcity of integrated, long-term (>4 week) studies on structural and functional alterations in the penis according to the period following cavernous nerve (CN) injury. The... -
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