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The Effects of Diazepam on the Carbachol Induced Contraction of the Isolated Rat Ileum

Kim JO, Kwon OC, Ha JH, Lee KY, Kim WJ

To investigate the effect of diazepam on the contractility of the intestinal smooth muscle, longitudinal muscle strip isolated from rat ileum was prepared for myography in isolated organ bath. 1) Basal...
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Effect of GABA on the Contractility of Canine Trachealis Muscle

Koo CH, Kwon OC, Choi EM, Lee KY, Kim WJ

This study aimed to investigate the existence of GABA receptor and the mechanisms of action of GABA and diazepam of the trachealis muscle isolated from dog. Horizontal muscle strips of...
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Effect of Baclofen on the Cholinergic Nerve Stimulation in Isolated Rat Detrusor

Lee KY, Lee KM, Choi EM, Choi HC, Ha JH, Kim WJ

This study aimed to investigate the mechanism of action of baclofen on the detrusor muscle isolated from rat. Rats (Sprague-Dawley) were sacrificed by decapitation and exsanguination. Horizontal muscle strips of...
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Characteristics of Potassium Channel in the Isolated Rat Detrusor Muscle

Jang MS, Choi EM, Ha JH, Lee KY, Kim WJ

The purpose of this study was to investigate the characteristics or the potassium channels existing in the rat urinary bladders. Smooth muscle strips of rat detrusor urinae were examined by isometric...
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Existance of cholinergic and purinergic receptor on the detrusor muscle of rat urinary bladder

Choi TS, Kwon OC, Ha JH, Lee KY, Kim WJ

This study was aimed at investigation of the stimulatory innervations on the rat urinary bladder. Detrusor muscle strips of 15 mm long were suspended in isolated muscle chambers containing 1...
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Effect of NG-nitro-L-arginine methyl ester and Methylene Blue on the Endotoxin-induced Vascular Hyporesponsiveness

Choi HC, Ha JH, Lee KY, Kim WJ, Sohn UD

  • KMID: 2320331
  • Yeungnam Univ J Med.
  • 1997 Dec;14(2):337-349.
The study was undertaken to examine the intensity of involvement of inducible nitric oxide synthase(iNOS) and cyclic GMP signal transduction pathway as one of the mechanisms of vaso-relaxative action of...
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Involvement of peripheral benzodiazepine receptor on contractility of canine trachealis muscle

Rhyu HY, Choi HC, Choi EM, Sohn UD, Lee KY, Kim WJ, Ha JH

  • KMID: 2285195
  • Korean J Physiol Pharmacol.
  • 1997 Dec;1(6):769-774.
Non-neuronal high affinity binding sites for benzodiazepines have been found in many peripheral tissues including cardiac muscle and vascular smooth muscle, and have been designated as 'peripheral benzodiazepine receptor'. Benzodiazepines have been shown...
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Capsaicin-Sensitive Sensory Nerves Indirectly Modulate Motor Function of the Urinary Bladder

Chang HH, Chang SJ, Hsieh CH, Hsu CK, Yang SS

PURPOSE: The urinary bladder (UB) is innervated by both sensory and autonomic nerves. Recent studies have shown that sensory neuropeptides induced contractions in the detrusor muscle. Therefore, in a mouse...
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