- The maintenance ability and Ca²⺠availability of skeletal muscle are enhanced by sildenafil
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Huang M, Lee KJ, Kim KJ, Ahn MK, Cho CH, Kim DH, Lee EH
- KMID: 2367554
- Exp Mol Med.
- 2016 Dec;48(12):e278.
- doi: 10.1038/emm.2016.134
Sildenafil relaxes vascular smooth muscle cells and is used to treat pulmonary artery hypertension as well as erectile dysfunction. However, the effectiveness of sildenafil on skeletal muscle and the benefit... -
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- The Expression of Cytokines and Chemokine mRNA by Human Skeletal Muscle Cell Line (SKM14)
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Joo IS, Huh K, Lee YB, Kim SU
- KMID: 1616354
- J Korean Neurol Assoc.
- 2003 Feb;21(1):89-96.
BACKGROUND: Muscle is a target of immunological injury in several muscle diseases, such as idiopathic inflammatory myopathy. However, it is also a target for gene therapy. Therefore, it is important... -
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- TRPC3 cation channel plays an important role in proliferation and differentiation of skeletal muscle myoblasts
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Woo JS, Cho CH, Kim DH, Lee EH
- KMID: 983954
- Exp Mol Med.
- 2010 Sep;42(9):614-627.
- doi: 10.3858/emm.2010.42.9.061
During membrane depolarization associated with skeletal excitation-contraction (EC) coupling, dihydropyridine receptor [DHPR, a L-type Ca2+ channel in the transverse (t)-tubule membrane] undergoes conformational changes that are transmitted to ryanodine receptor... -
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- p38 MAPK Participates in Muscle-Specific RING Finger 1-Mediated Atrophy in Cast-Immobilized Rat Gastrocnemius Muscle
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Kim J, Won KJ, Lee HM, Hwang BY, Bae YM, Choi WS, Song H, Lim KW, Lee CK, Kim B
- KMID: 2285386
- Korean J Physiol Pharmacol.
- 2009 Dec;13(6):491-496.
- doi: 10.4196/kjpp.2009.13.6.491
Skeletal muscle atrophy is a common phenomenon during the prolonged muscle disuse caused by cast immobilization, extended aging states, bed rest, space flight, or other factors. However, the cellular mechanisms... -
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- Stem Cell Research in Cardiovascular System
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Choi SC, Lim DS
- KMID: 2030757
- Korean J Anat.
- 2004 Apr;37(2):133-140.
Myocardial infarction leads to loss of tissue and impairment of cardiac performance. Because cardiomyocytes have a limited ability to self-renewal, and thus the transplantation of adult stem cells into infarcted... -
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- Expression of Caveolin-3 in the Muscle Cell and Tissue
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Kwon BS, Lee SJ, Hyun JK, Jun DJ, Joo HW, Kim BH, Shin DH
- KMID: 2323855
- J Korean Acad Rehabil Med.
- 2003 Jun;27(3):382-387.
OBJECTIVE: Caveolae are the microdomain of the plasma membrane that have been implicated in signal transduction and caveolin is a principal component of the caveolae. Caveolin-3, a family of caveolin... -
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- Current Concepts in Stem Cell Therapy for Cardiovascular Diseases: What We Know and Don't Know
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Jeon KH
- KMID: 2129478
- Hanyang Med Rev.
- 2015 Nov;35(4):242-249.
- doi: 10.7599/hmr.2015.35.4.242
Medical therapies and mechanical interventions for the treatment of myocardial infarction (MI) and ischemic heart failure have seen great progress. However, current therapies only slow the progression to heart failure,... -
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- Sumoylation of histone deacetylase 1 regulates MyoD signaling during myogenesis
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Joung H, Kwon S, Kim KH, Lee YG, Shin S, Kwon DH, Lee YU, Kook T, Choe N, Kim JC, Kim YK, Eom GH, Kook H
- KMID: 2438357
- Exp Mol Med.
- 2018 Jan;50(1):e427.
- doi: 10.1038/emm.2017.236
Sumoylation, the conjugation of a small ubiquitin-like modifier (SUMO) protein to a target, has diverse cellular effects. However, the functional roles of the SUMO modification during myogenesis have not been... -
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- Stem Cell Therapy for Patients with Myocardial Infarction
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Kim HS
- KMID: 2184728
- J Korean Med Assoc.
- 2006 Nov;49(11):1035-1045.
- doi: 10.5124/jkma.2006.49.11.1035
Several randomized placebo controlled clinical trials, which were based on the solid data from cell biologic, animal, and phase 1 clinical trials, have been published to demonstrate the efficacy of... -
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- Topical application of epidermal growth factor accelerates wound healing by myofibroblast proliferation and collagen synthesis in rat
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Kwon YB, Kim HW, Roh DH, Yoon SY, Baek RM, Kim JY, Kweon HY, Lee KG, Park YH, Lee JH
- KMID: 1059193
- J Vet Sci.
- 2006 Jun;7(2):105-109.
- doi: 10.4142/jvs.2006.7.2.105
Recombinant human epidermal growth factor (rhEGF) stimulates the proliferation and migration of epithelial cells in human cell culture systems and animal models of partial-thickness skin wounds. This study investigated the effect of a topical... -
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