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Passive Skeletal Muscle Excursion after Tendon Rupture Correlates with Increased Collagen Content in Muscle

Koh IH, Kang HJ, Jeon SW, Park JH, Choi YR

PURPOSE: This study was designed to measure time-dependent changes in muscle excursion and collagen content after tenotomy, and to analyze the correlation between muscle excursion and collagen content in a...
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Iron Supplementation in Experimental Hyperthyroidism: Effects on Oxidative Stress in Skeletal Muscle Tissue

Seymen HO, Civelek S, Seven A, Yigit G, Hatemi H, Burcak G

This study was designed to investigate the effects of iron supplementation on the parameters of oxidative stress in the skeletal muscle tissue of hyperthyroidism induced rats. Hyperthyroidism was found to...
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Fast and slow gating types of SR ryanodine receptor/channel purified from canine latissimus dorsi muscle

Shin JH, Yoo GH, Lee CJ, Suh CK

The ryanodine receptor/channel (RyR) mediates the release of calcium from the sarcoplasmic reticulum (SR) in both skeletal and cardiac muscle cells. There are three isoforms of the RyR: RyR1, RyR2,...
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The Correlation between Insulin Resistance and the Visceral Fat to Skeletal Muscle Ratio in Middle-aged Women

Kim CS, Nam JY, Park JS, Kim DM, Yoon SJ, Ahn CW, Lim SK, Kim KR, Lee HC, Huh KB, Cha BS

Central obesity with visceral fat accumulation and the amount of skeletal muscle mass may influence insulin sensitivity via its capacity for glucose load uptake. We investigated the relationships among the...
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Delivery of Factor VIII Gene into Skeletal Muscle Cells Using Lentiviral Vector

Jeon HJ, Oh TK, Kim OH, Kim ST

PURPOSE: This study was designed to investigate whether transduction of lentiviral vectors (LV) carrying human coagulation factor VIII (hFVIII) cDNA into skeletal muscle could increase circulating hFVIII concentrations. MATERIALS AND...
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Changes in Muscular Lipids in Unilateral Isolated Hypertrophy of Gastrocnemius Muscle Can Be Revealed by 1H MR Spectroscopy

Brechtel K, Machann J, Pick M, Schaefer J, Claussen C, Schick F

OBJECTIVE: To test whether proton magnetic resonance spectroscopy (1H-MRS) reveals changes in the lipid content of the gastrocnemius muscle (GM) and soleus muscle (SOL) of a patient with unilateral isolated...
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Aging impairs insulin-stimulated glucose uptake in rat skeletal muscle via suppressing AMPKalpha

Qiang W, Weiqiang K, Qing Z, Pengju Z, Yi L

  • KMID: 756077
  • Exp Mol Med.
  • 2007 Aug;39(4):535-543.
Insufficient intracellular fat oxidation is an important contributor to aging-related insulin resistance, while the precise mechanism underlying is unclear. AMP-activated protein kinase (AMPK) is an important regulator of intracellular fat...
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Cathepsin L derived from skeletal muscle cells transfected with bFGF promotes endothelial cell migration

Chung JH, Im EK, Jin T, Lee SM, Kim SH, Choi EY, Shin MJ, Lee KH, Jang Y

Gene transfer of basic fibroblast growth factor (bFGF) has been shown to induce significant endothelial migration and angiogenesis in ischemic disease models. Here, we investigate what factors are secreted from...
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