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Activities of Hepatic Enzymes for Ethanol Metabolism in Cholestatic Rats with Acute Ethanol Intoxication

Mun KC, Kwak CS, Jo YH

  • KMID: 2304643
  • Korean J Gastroenterol.
  • 1999 Jul;34(1):50-55.
No abstract available.
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Verification of learner’s differences by team-based learning in biochemistry classes

Mun KH, Mun KC

PURPOSE: We tested the effect of team-based learning (TBL) on medical education through the second-year premedical students’ TBL scores in biochemistry classes over 5 years. METHODS: We analyzed the results based...
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Effect of Melatonin on Hemolysis Induced by Cyclosporine

Kwak CS, Mun KC, Suh SI

  • KMID: 1264081
  • Korean J Nephrol.
  • 2001 Sep;20(5):838-841.
Hemolysis is one of the side effects of cyclosporine(CsA). Some experimental and clinical data have strongly suggested that CsA-induced hemolysis is resulted from the increased production of free radical species...
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Effect of Immunosuppressive Drugs on the Metalloproteinase in the Glioma Cells and Osteoblasts

Mun KC

The matrix metalloproteinases (MMPs) play a key role in the normal physiology of connective tissue during development, morphogenesis, and wound healing. Dysregulation of their activity has been implicated in numerous...
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Damage Induced by Oxygen Free Radicals in the Cell Fractionation of Regenerating Liver

Park HY, Mun KC

  • KMID: 2038324
  • Korean J Gastroenterol.
  • 2002 Apr;39(4):284-288.
BACKGROUND/AIMS: Oxygen free radicals can be defined as oxygen molecules or molecular fragments that have an unpaired electron. They are formed in all living organisms during physiological and pathophysiological metabolism,...
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Effect of Cyanate on Lens Protein Carbamylation and Catalase Activuty

Mun KC, Lee SY

  • KMID: 2336777
  • J Korean Ophthalmol Soc.
  • 1999 Feb;40(2):369-375.
Proteins are known to be carbamylated as a result of reactions with ureaderived cyanate. We investigated the effect of carbamylation by cyanate on the catalase activity which is known that...
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Metabolism of Oxygen Free Radicals in the Regenerating Liver of Rats

Park SK, Park HY, Mun KC, Kim YH, Kwak CS

  • KMID: 1647121
  • Korean J Gastroenterol.
  • 2002 Oct;40(4):255-262.
BACKGROUND/AIMS: To know the metabolism of oxygen free radicals in the regenerating liver, the 70% (median and left lateral lobes) partial hepatectomy was performed in the Sprague-Dawley rats. METHODS: The original...
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Effect of Amino Acids and Albumin on Damage Induced by Cyanate in Osteoblast

Park KD, Park SB, Choi HJ, Mun KC, Kim HC

  • KMID: 2079744
  • Korean J Nephrol.
  • 2007 Jul;26(4):404-413.
PURPOSE: Cyanate, known as one of the uremic toxins and derived spontaneously from urea, has several effects on the biologic substances including erythropoietin, antioxidant and ceruloplasmin. To find out the...
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Metabolism of Reactive Oxygen Species in Neutrophils from Patients with End-Stage Renal Disease

Choi HJ, Kwon JK, Mun KC, Chang EJ, Kwak CS, Han SY, Hwang EA, Park SB, Kim HC

  • KMID: 2079400
  • Korean J Nephrol.
  • 2004 May;23(3):429-438.
BACKGROUND: The present study was aimed to know the cause of impaired bactericidal activity, especially the metabolism of oxygen free radicals in neutrophils from patients with end-stage renal disease (ESRD)....
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Effect of Melatonin on the Cisplatin Induced Ototoxicity in Rats

Kim JG, Park SH, Nam SI, Chang EJ, Mun KC, Kim SP

  • KMID: 2276043
  • Korean J Otolaryngol-Head Neck Surg.
  • 2003 Oct;46(10):808-814.
BACKGROUND AND OBJECTIVES: Cisplatin (CP), an antitumor agent widely used in the treatment of head and neck cancers, has side effects such as ototoxicity and nephrotoxicity. These side effects are...
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Effect of Hemodialysis on Levels of Malondialdehyde and Antioxidant Enzymes in Erythrocytes from Patients with End Stage Renal Disease

Mun KC, Joo I, Kim YH, Park SB, Kim HC

  • KMID: 2254642
  • Korean J Nephrol.
  • 1998 Jul;17(4):591-596.
To clarify the mechanism of the protective effect of hemodialysis on lipid peroxidation in RBC membrane structures, the level of malondialdehyde (MDA) which is the lipid peroxidation product, and the...
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Changes of Catecholamine Metabolic Enzymes in Rat Liver during 2 Weeks of Head-down Suspension

Bae JH, Mun KC

  • KMID: 1544401
  • Korean J Aerosp Environ Med.
  • 1997 Sep;7(3):44-49.
During simulated weightlessness and spaceflight, variations in plasma and urinary catecholamine(GA) levels haute been observed. The alterations of metabolism of CA In liver, the main site of metabolism, ate yet...
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Activities of Hepatic Antioxidant Enzymes in Bile Duct Ligates Rats

Mun KC, Kwak CS

  • KMID: 1891135
  • Korean J Gastroenterol.
  • 1997 Jul;30(1):66-71.
BACKGROUND AND AIMS: Protective role of antioxidant enzymes under the cholestasis was evaluated. METHODS:: The activity of xanthine oxidase, the amount of superoxide radical production, and the activities of antioxidant...
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Protective Effect of Melatonin on the Nephrotoxicity by Cisplatin

Choi HJ, Shin YH, Mun KC, Song DK, Kim IC, Seo SH, Kwak CS, Chang EJ, Kim HC

  • KMID: 2254355
  • Korean J Nephrol.
  • 2004 Mar;23(2):205-212.
BACKGROUND: Cisplatin (CP), an antitumor agent widely used in the treatment of cancers, has nephrotoxicity. This side effect is closely related to oxidative stress. In the present study, we attempted...
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The protective effect of allopurinol on cholestatic liver injury induced by bile duct ligation

Mun KC, Kwak CS, Kwon KY

To determine whether oxygen free radicals are responsible for the pathogenesis of the cholestasis induced by ligation of common bile duct (CBD) variables which reflect the hepatic function in the...
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Effect of Cu Zn Levels on Superoxide Dismutase Activity in Erythrocytes from Patients with end Stage Renal Disease

Mun KC, Kwon JK

  • KMID: 1990079
  • Korean J Nephrol.
  • 1999 Mar;18(2):265-269.
Suppressed superoxide dismutase activity, which is responsible for the dismutation of superoxide anion to hydrogen peroxide, is known to be one of the factors leading to lipid peroxidation in the erythrocyte membrane...
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Effect of Melatonin on the Diabetes Mellitus Induced by Streptozotocin in Rats

Lee RR, Kim YH, Kwak CS, Yeo MY, Mun KC

  • KMID: 2008278
  • J Korean Diabetes Assoc.
  • 2002 Oct;26(5):357-365.
BACKGROUND: Oxygen free radicals are related to the pathogenesis and development of diabetes mellitus. The effect of melatonin, a known powerful antioxidant, was studied diabetes mellitus induced by streptozotocin in...
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Impact of calcineurin inhibitors on rat glioma cells viability

Seong JH, Park WY, Paek JH, Park SB, Han S, Mun KC, Jin K

BACKGROUND: Although kidney transplantation outcomes have improved dramatically after using calcineurin inhibitors (CNIs), CNI toxicity continues to be reported and the mechanism remains uncertain. Here, we investigated the neurotoxicity of...
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Mechanism of Renal Oxidative Damage following 4-week Head-down Suspension in Rats

Bae JH, Mun KC, Kwak CS, Song DK, Park WK

  • KMID: 2298549
  • Korean J Aerosp Environ Med.
  • 2000 Jun;10(2):113-119.
The purpose of this study was to observe the variation of malondialdehyde (MDA), an indirect index of oxidative damage, following 4-week of head-down suspension (HDS) at -45degreein rats as a...
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Activities of Hepatic Antioxidant Enzymes in Rats during 14 Days of Head-down Suspension as a Model of Simulated Weightlessness

Bae JH, Park WK, Song DK, Chae EU, Kwak CS, Kim YH, Mun KC

  • KMID: 2092978
  • Korean J Aerosp Environ Med.
  • 1997 Dec;7(4):44-50.
Cells and tissues of human and animal are protected against free radicals by several complex mechanisms including the action of antioxidant enzymes, such as superoxide dismutase (SOD), glutathione peroxidase (GSH-Px)...
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