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Bronchial Response to High and Low Molecular Weight Occupational Inhalant Allergens

Lipińska-Ojrzanowska A, Nowakowska-Świrta E, Wiszniewska M, Walusiak-Skorupa J

PURPOSE: Occupational asthma may be induced by high- or low-molecular weight allergens (HMWA or LMWA, respectively). The study was conducted to compare the pattern of bronchial response in 200 HMWA-induced...
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Quantification of Cell-Free DNA: A Comparative Study of Three Different Methods

Jeon K, Lee J, Lee JS, Kim M, Kim HS, Kang HJ, Lee YK

BACKGROUND: Cell-free DNA (cfDNA) provides unique potential as a biomarker for cancer patients or in the field of prenatal care. Following extraction from plasma, cfDNA should be quantified before downstream...
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Identification and Characterization of Two New S-Adenosylmethionine-Dependent Methyltransferase Encoding Genes Suggested Their Involvement in Stipe Elongation of Flammulina velutipes

Huang Q, Mukhtar I, Zhang Y, Wei Z, Han X, Huang R, Yan J, Xie B

Two new SAM-dependent methyltransferase encoding genes (fvsmt1 and fvsmt2) were identified from the genome of Flammulina velutipes. In order to make a comprehensive characterization of both genes, we performed in...
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Production of polyclonal antibody against kidney antigens: a model for studying autoantibody in feline chronic kidney diseases

Songaksorn N, Petsophonsakul W, Pringproa , Lampang KN, Sthitmatee N, Sriphawattana N, Thongkorn

Chronic kidney disease is considered to be most common in geriatric domestic cats. It has been reported that the feline viral rhinotracheitis, calicivirus, and panleukopenia (FVRCP) vaccine prepared from the...
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Hyaluronic acid has chondroprotective and joint-preserving effects on LPS-induced synovitis in horses

Neuenschwander HM, Moreira JJ, Vendruscolo CP, Fülber J, Seidel SR, Michelacci YM, Baccarin R

The intra-articular use of hyaluronic acid (HA) for the treatment of synovitis and osteoarthritis is still controversial. As a consequence, corticosteroids remain the most frequently employed therapeutic agents, despite their...
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Expression and serological application of recombinant epitope-repeat protein carrying an immunodominant epitope of Newcastle disease virus nucleoprotein

Gaikwad SS, Lee HJ, Kim JY, Choi KS

PURPOSE: The aim of the present study was to develop a serodiagnostic test for differentiation infected from vaccinated animal (DIVA) strategy accompanying the marker vaccine lacking an immunodominant epitope (IDE)...
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Biocontrol of Orchid-pathogenic Mold, Phytophthora palmivora, by Antifungal Proteins from Pseudomonas aeruginosa RS1

Sowanpreecha R, Rerngsamran P

Black rot disease in orchids is caused by the water mold Phytophthora palmivora. To gain better biocontrol performance, several factors affecting growth and antifungal substance production by Pseudomonas aeruginosa RS1...
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Comparative Characterization of Four Calcium-Binding EF Hand Proteins from Opisthorchis viverrini

Emmanoch P, Kosa N, Vichasri-Grams S, Tesana S, Grams R, Geadkaew-Krenc A

Four isoforms of calcium binding proteins containing 2 EF hand motifs and a dynein light chain-like domain in the human liver fluke Opisthorchis viverrini, namely OvCaBP1, 2, 3, and 4,...
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Detecting Allergens From Black Tiger Shrimp Penaeus monodon That Can Bind and Cross-link IgE by ELISA, Western Blot, and a Humanized Rat Basophilic Leukemia Reporter Cell Line RS-ATL8

Jarupalee , Chatchatee P, Komolpis K, Suratannon N, Roytrakul , Yingchutrakul Y, Yimchuen W, Butta P, Jacquet A, Palaga T

BACKGROUND: Black tiger shrimp Penaeus monodon is one of the common causes of shellfish allergy that is increasing worldwide. One of the important problems in the management of shellfish allergy...
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Protective Effects of Cinnamic Acid Derivatives on Gastric Lesion

Lee SY, Hwang IY, Jeong CS

P-methoxycinnamic acid and 3,4,5-trimethoxycinnamic acid are the compounds found in Polygalae Radix, the root of Polygala tenuifolia Willdenow, and have been reported to have hepatoprotective and anti-neurodegenerative effects. On the...
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Local Delivery of CTGF siRNA with Poly(sorbitol-co-PEI) Reduces Scar Contraction in Cutaneous Wound Healing

Cho KH, Singh B, Maharjan1 , Jang Y, Choi YJ, Cho CS

Healing process in scarring inevitably produces a considerable amount of non-organized dense collagen-rich matrix called scar thus impairing the native structure of skin. Connective tissue growth factor (CTGF) overexpression within...
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Hylan GF-20 Viscosupplementation in the Treatment of Symptomatic Osteoarthritis of the Knee: Clinical Effect Survivorship at 5 Years

Boutefnouchet T, Puranik G, Holmes E, Bell KM

PURPOSE: Controversies remain surrounding the choice of hyaluronic acid products and patient selection. A study was conducted to report the long-term survivorship of intra-articular injection effect of high molecular weight...
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Development and properties of hypoallergenic infant formula

Ha WK, Lee J, Kim KE

Milk proteins are composed of casein, further classified into αS1-casein, αS2-casein, β-casein, and κ-casein, and whey protein, which is separated into α-lacatalbumin, β-lactoglobulin, serum albumin, and some minor proteins, such...
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Rheological study of hyaluronic acid derivatives

Chernos M, Grecov D, Kwok E, Bebe S, Babsola O, Anastassiades T

The viscoelastic properties of four novel, low molecular weight hyaluronic acid derivatives were investigated and compared to the parent hyaluronic acid compound. Briefly, all derivatives were synthesized by first deacetylating...
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Levels of common salivary protein 1 in healthy subjects and periodontal patients

Heo SM, Lee S, Wang H, Jeong JH, Oh SW

PURPOSE: Human saliva, as a vital part of the immune defense system, contains a number of distinct proteins and peptides. Recently human common salivary protein 1 (CSP1) has been identified...
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The Mechanical Effect of Rod Contouring on Rod-Screw System Strength in Spine Fixation

Acar N, Karakasli , Karaarslan AA, Ozcanhan M, Ertem F, Erduran M

OBJECTIVE: Rod-screw fixation systems are widely used for spinal instrumentation. Although many biomechanical studies on rod-screw systems have been carried out, but the effects of rod contouring on the construct...
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Hornerin Is Involved in Breast Cancer Progression

Choi J, Kim DI, Kim J, Kim BH, Kim A

PURPOSE: The S100 gene family, which comprises over 20 members, including S100A1, S100A2, S100A8, S100A9, profilaggrin, and hornerin encodes low molecular weight calcium-binding proteins with physiological and pathological roles in...
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Physical and biochemical characteristics of allergens

Jeong KY

What makes a certain molecule to elicit allergic responses? It has been a long-running question in allergology and immunology. Molecular properties of allergens have been characterized for last 30 years....
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Sensitization to silk allergen among workers of silk filatures in India: a comparative study

Gowda G, Shivalingaiah AH, Vijayeendra AM, Sarkar N, Nagaraj C, Masthi NR

BACKGROUND: Sericulture plays an eminent role in development of rural economy in India. Silk filature is a unit where silk is unwound from the cocoons and the strands are collected...
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Brain metastasis in human epidermal growth factor receptor 2-positive breast cancer: from biology to treatment

Koo T, Kim IA

Overexpression of human epidermal growth factor receptor 2 (HER2) is found in about 20% of breast cancer patients. With treatment using trastuzumab, an anti-HER2 monoclonal antibody, systemic control is improved....
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