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Radiolabeling Methods Used for Preparation of Molecular Probes

Choe YS

  • KMID: 2078803
  • Korean J Nucl Med.
  • 2004 Apr;38(2):121-130.
Molecular imaging visualizes cellular processes at a molecular or genetic level in living subjects, and diverse molecular probes are used for this purpose. Radiolabeling methods as well as radioisotopes are...
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Optical Molecular Imaging for Diagnosing Intestinal Diseases

Kim SY, Myung SJ

  • KMID: 2165421
  • Clin Endosc.
  • 2013 Nov;46(6):620-626.
Real-time visualization of the molecular signature of cells can be achieved with advanced targeted imaging techniques using molecular probes and fluorescence endoscopy. This molecular optical imaging in gastrointestinal endoscopy is...
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Nuclear Medicine Techniques

Lee KH

Molecular imaging is emerging as an exciting new discipline that deals with imaging of disease on a cellular or genetic level. Nuclear medicine has tra6 tionally focused on noninvasive imaging...
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Nuclear Medicine in Oncology

Choi CW

Nuclear oncolgy is important in the diagnosis, staging, and long-term surveillance of a number of cancers. Over the past 10 years there has been an explosion of new radioisotopic tracers...
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Review: optically-triggered phase-transition droplets for photoacoustic imaging

Chen Q, Yu J, Kim K

Optically-triggered phase-transition droplets have been introduced as a promising contrast agent for photoacoustic and ultrasound imaging that not only provide significantly enhanced contrast but also have potential as photoacoustic theranostic...
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Advances in the Endoscopic Assessment of Inflammatory Bowel Diseases: Cooperation between Endoscopic and Pathologic Evaluations

Cheon JH

Endoscopic assessment has a crucial role in the management of inflammatory bowel disease (IBD). It is particularly useful for the assessment of IBD disease extension, severity, and neoplasia surveillance. Recent...
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Effect of Manganese on primary rat calvarial cell

Kim JE, Kim YJ, Chung HJ, Kim OS

Chronic exposure to high levels of manganese leads a pronounce and debilitating disorder known as manganism. Research on the toxic manifestation of manganese have focused primarily on its neurological effects...
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The Effect of RGP Lens and Reverse Geometry Lens on Redistribution of Corneal Epithelial Cell in Rabbit

Jeong YJ, Lee HB, Park SP

  • KMID: 2338598
  • J Korean Ophthalmol Soc.
  • 2014 Jan;55(1):110-118.
PURPOSE: To investigate the migration and redistribution of rabbit corneal epithelial cells when wearing reverse geometry lens (RGL) or rigid gas permeable lens (RGP). METHODS: In 30 rabbits, the right eyes...
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Resurrection of antibody as a therapeutic drug

Chung HK, Chung JH

Currently 18 monoclonal antibodies were approved by FDA for inj ection into humans for therapeutic or diagnostic purpose. And 146 clinical trials are under way to evaluate the efficacy of...
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Effects of Oxygen Free Radical on the In-vitro Development of Human Embryos

Hwang KJ, Yoo JH, Kwon HC, Yang HW, Ryu HS, Chang KH, Sohn SH, Oh KS

  • KMID: 2075300
  • Korean J Obstet Gynecol.
  • 1997 Sep;40(9):1821-1828.
INTRODUCTION: In human IVF-ET only a few oocytes develop to be good quality embryos depending on the incubation conditions and the quality of ovum and sperm, while the rest show...
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Evaluation of alpha-Tubulin as an Antigenic and Molecular Probe to Detect Giardia lamblia

Kim J, Shin MH, Song KJ, Park SJ

The alpha/beta-tubulin heterodimer is the basic subunit of microtubules in eukaryotes. Polyclonal antibodies specific to recombinant alpha-tubulin of Giardia lamblia were made, and found effective as a probe to specifically...
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Nucleotide sequence analysis of HTLV-I isolate from a Korean patient with HAM/TSP

Saito M, Moritoyo T, Park JH, Lee BI, Kim JS, Fujisawa J, Osame M, Yoshida M

Limited nucleotide sequences of human T-cell lymphotropic virus type I (HTLV-1) provirus isolated from the first case of a Korean patient with HTLV-I associated myelopathy and tropical spastic paraparesis (HAM/TSP)...
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Ischemia-responsive Protein(irp94) Gene Expression in a Neuronal Cell Culture Model of Ischemia

Kim SH, Yang YM, Ha YR, Chung SP, Yoo IS, Kim IB

  • KMID: 2100588
  • J Korean Soc Emerg Med.
  • 2001 Sep;12(3):201-206.
BACKGROUND: The ischemia responsive protein 94 kDa(irp94) gene belongs to the heat shock protein 110 family and was isolated in 1999 from rat brain by transiently induced forebrain ischemia. The...
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Analysis of p53 tumor suppressor gene mutations and human papillomavirus infection in human bladder cancers

Kim KH, Kim YS

To determine whether the dysfunction of p53 caused either by mutation of the p53 gene itself or by binding to E6 protein of oncogenic HPVs is involved in the transitional...
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Mutations in the pre-core region of hepatitis B virus DNA in patients with chronic liver diseases

Kim WH, Kim KH, Chung JP, Kang JK, Park IS

To investigate the prevalence of point mutation in the pre-core (pre-C) region of hepatitis B virus (HBV) DNA, we performed dot blot hybridization and sequencing of enzymatically amplified HBV DNA...
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Discrepancy in T cell clonal expansions in synovial fluid and peripheral blood from rheumatoid arthritis patients

Choi IH, Chwae Y, Lee SK, Chu M, Kim JD, Kim SJ

Rheumatoid arthritis (RA) is an autoimmune disease involving the synovial membrane of peripheral joints. T cells specific for self antigens may play a critical role. Identification of T cell receptors...
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Prenatal fetal sex determination from maternal peripheral blood using polymerase chain reaction

Yang YH, Yoo HS, Kim IK

We have investigated the use of a nested polymerase chain reaction(PCR) assay with Y-specific sequence from the DYS 14 locus on the short arm of Y-chromosome for prenatal sex determination...
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