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The changes of mitochondrial cytochrome c and GABAergic neuron in neuropathic pain model

Kim WS, Park JY, Kim TK, Baik SW

BACKGROUND: Role of cytochrome c (Cyt c) is an apoptogenic agent under certain conditions. The mitochondrial permeability transition pore (MPTP) plays an important role in cell death since it opens,...
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The Formation of Giant Mitochondria in the Liver Cells Induced by Hydrazine

Kwon IH, Lee JG, Sohn YK, Sohn TJ

  • KMID: 2274855
  • Korean J Pathol.
  • 1986 Sep;20(3):288-294.
The authors studied the formation of giant mitochondria in liver cell. The Sprague Dawley rats were sacrificed following intervals; 5, 10, 20, 30, and 60 minutes after intraperitoneal injection of...
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Electron Microscopic Study on Mitochondria and Cytochrome Oxidase Activity Following Acute Carbon Monoxide Exposure in Rat Myocardium

Chong DY, Lee Y, Cho SH, Song KY

The problem of carbon monoxide intoxication has been increasing since 1950s and it is still regarded as one of the most serious public health problem in Korea. If the patients...
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Experimental Aconitine Optic Neuropathy

Kim SD, Kim SH

  • KMID: 2122962
  • J Korean Ophthalmol Soc.
  • 1990 May;31(5):661-679.
Effects of aconitine on the retina and optic nerve were studied in rabbits by means of visual evoked potential(VEP), electroretinogram(ERG), and electron microscopy. Aconitine(0.4mg/kg) was administered intra peritoneally. The effects...
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Retnal Toxicty of Intravitreal Tissue Plasminogen Activator with C3F8 Injection in Rabbit Eyes

Kim KS, Rhee K, Huh K

  • KMID: 2125996
  • J Korean Ophthalmol Soc.
  • 2004 Jul;45(7):1181-1188.
PURPOSE: To determine the concentration at which a mixed injection of tissue plasminogen activator (tPA) and C3F8 gas is toxic, we studied the histopathological changes in the rabbit retina. METHODS:...
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Matrine Suppresses Pancreatic Fibrosis by Regulating TGF-β/Smad Signaling in Rats

Liu P, Zhu L, Zou G, Ke H

PURPOSE: This study aimed to elucidate the molecular mechanisms of the anti-pancreatic fibrosis effects of matrine in rats. MATERIALS AND METHODS: Trinitrobenzene sulfonic acid was administrated to rats to establish a...
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The Effect of Mitomycin C(MMC) on Sinus Mucosal Openings in Rabbits

Kim BK, Chung WS

  • KMID: 2206015
  • J Korean Ophthalmol Soc.
  • 2001 Jul;42(7):1016-1029.
PURPOSE: This experimental study investigates the effect of mitomycin C(MMC) on the healing of sinus mucosal opening. METHODS: One hundred and twenty rabbits were used and divided into 8 groups...
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Histological Changes in the Heart-Lung Preparation by the Autoperfusion

Han SS

The experimental study for extracorporeal preservation of the autoperfused working heart-lung preparation was performed in 5 dogs. Their weights were between 14??6kg, average of 14.8kg. The preparations were observed from...
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Two Case of Sudoriparous Angioma

Choi GJ, Cho KH, Houh D, Kim HO, Kim CW

  • KMID: 1678636
  • Korean J Dermatol.
  • 1982 Dec;20(6):957-964.
Sudoriparous angioma is an unusual form of angioma with pain and hyperhidrosis. We present two cases of typical sudoriparous angioma. Case 1: 9-year-old female showed 0. 8 to 2. 0cm...
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Inhibition of Corneal Angiogenesis by Orally Administered Thalidomide

Lee JY, Kim JM, Choi TH, Kim JW

  • KMID: 2108325
  • J Korean Ophthalmol Soc.
  • 1997 Dec;38(12):2098-2107.
Thalidomide, a potent teratogen, is Known as an angiogenic inhibitor. This study was performed to examine the effect of thalidomide on corneal angiogenesis in rabbit cornea induced by chemical cauterization....
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Changes of Blood-Retinal Barrier Induced by Destruction of the Retinal Pigment Epithelium

Kim MM, Hahn DK, Sohn TJ, Kwak JS

  • KMID: 2122743
  • J Korean Ophthalmol Soc.
  • 1987 Aug;28(4):759-773.
The author studied the functional derangement of blood-retinal barrier induced by destruction of the pigment epithelial cells of the retina. Sodium iodate, which was well known to exert a selectively...
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Cell-in-Cell Death Is Not Restricted by Caspase-3 Deficiency in MCF-7 Cells

Wang S, He M, Li L, Liang Z, Zou Z, Tao A

PURPOSE: Cell-in-cell structures are created by one living cell entering another homotypic or heterotypic living cell, which usually leads to the death of the internalized cell, specifically through caspase-dependent cell...
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Morphologic changes in the spinal cord following intrathecal palonosetron-HCl injection in rats

Yoo SH, Chung JH, Seo Y, Choi MK, Choi WK, Kim JB

BACKGROUND: Intravenous palonosetron-HCl, a second-generation antagonist of selective serotonin type 3 (5-HT3) receptors, can prevent chemotherapy-induced nausea and vomiting (CINV) and postoperative nausea and vomiting (PONV). 5-HT3 receptors are abundant...
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Prevention of Diabetes by Fenofibrate in OLETF Rats: Hepatic Mechanism for Reducing Visceral Adiposity

Lee HJ, Park MK, Lee KI, An YJ, Kim JM, Park JY, Han Y, Hong SH, Choi SS, Yoo YH, Suh JD, Kim DK

BACKGROUND: The aim of this study is to evaluate the hepatic mechanism of fenofibrate that has the diabetes protective action in rats. METHODS: We chose OLETF rats and divided them...
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The Changes of Cerebral Metabolic Parameters, Serum Levels of Neuron-Specific Enolase and S-100beta Protein During Retrograde Cerebral Perfusion Under Profound Hypothermic Total Circulatory Arrest

Kim KH, Lee JI

  • KMID: 1877917
  • Korean J Thorac Cardiovasc Surg.
  • 2001 Sep;34(9):653-661.
BACKGROUND: Retrograde cerebral perfusion(RCP) is one of the methods used for brain protection during aortic arch surgery. The author previously published the data, however, for the safety of it, there...
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