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Silver Nanoparticles as a Smart Antimicrobial Agent

Yang EJ, Jang J, Kim S, Choi IH

In modern medicine the resistance to conventional antibiotics is becoming a serious concern due to high instances of mortality. Several metallic nanoparticles are suggested as promising anti-microbial agents against multidrug-resistant...
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Phagocytosis and Endocytosis of Silver Nanoparticles Induce Interleukin-8 Production in Human Macrophages

Kim S, Choi IH

Phagocytosis or endocytosis by macrophages is critical to the uptake of fine particles, including nanoparticles, in order to initiate toxic effects in cells. Here, our data enhance the understanding of...
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Platinum nanoparticles reduce ovariectomy-induced bone loss by decreasing osteoclastogenesis

Kim WK, Kim JC, Park HJ, Sul OJ, Lee MH, Kim JS, Choi HS

  • KMID: 1397447
  • Exp Mol Med.
  • 2012 Jul;44(7):432-439.
Platinum nanoparticles (PtNP) exhibit remarkable antioxidant activity. There is growing evidence concerning a positive relationship between oxidative stress and bone loss, suggesting that PtNP could protect against bone loss by...
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Exposure to Cerium Oxide Nanoparticles Is Associated With Activation of Mitogen-activated Protein Kinases Signaling and Apoptosis in Rat Lungs

Rice KM, Nalabotu S, Manne ND, Kolli MB, Nandyala G, Arvapalli , Ma JY, Blough ER

OBJECTIVES: With recent advances in nanoparticle manufacturing and applications, potential exposure to nanoparticles in various settings is becoming increasing likely. No investigation has yet been performed to assess whether respiratory...
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Highly Sensitive and Novel Point-of-Care System, aQcare Chlamydia TRF Kit for Detecting Chlamydia trachomatis by Using Europium (Eu) (III) Chelated Nanoparticles

Ham JY, Jung J, Hwang BG, Kim WJ, Kim YS, Kim EJ, Cho MY, Hwang MS, Won DI, Suh JS

BACKGROUND: The bacterium Chlamydia trachomatis is one of the leading causes of sexually transmitted diseases worldwide. Since no simple and effective tool exists to diagnose C. trachomatis infections, we evaluated...
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In vivo Tracking of Mesenchymal Stem Cells Labeled with a Novel Chitosan-coated Superparamagnetic Iron Oxide Nanoparticles using 3.0T MRI

Reddy AM, Kwak BK, Shim HJ, Ahn C, Lee HS, Suh YJ, Park ES

This study aimed to characterize and MRI track the mesenchymal stem cells labeled with chitosan-coated superparamagnetic iron oxide (Chitosan-SPIO). Chitosan-SPIO was synthesized from a mixture of FeCl2 and FeCl3. The...
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Size Control of 99mTc-tin Colloid Using PVP and Buffer Solution for Sentinel Lymph Node Detection

Kim EM, Lim ST, Sohn MH, Jeong HJ

Colloidal particle size is an important characteristic that allows mapping sentinel nodes in lymphoscintigraphy. This investigation aimed to introduce different ways of making a 99mTc-tin colloid with a size of...
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Comparison of the Efficacies of Silver-Containing Dressing Materials for Treating a Full-Thickness Rodent Wound Infected by Methicillin-resistant Staphylococcus aureus

Lee JH, Chae JD, Kim DG, Hong SH, Lee WM, Ki M

BACKGROUND: Methicillin-resistant Staphylococcus aureus (MRSA) may cause infections during wound dressing. We aimed to compare the antibacterial activities and wound-healing effects of commercially available silver-coated or silver-impregnated wound dressings on...
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