- Cloning and sequencing of p33 in a Korean isolate of Theileria sergenti
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Kang SW, Choi EJ, Kweon CH
- KMID: 1715324
- Korean J Parasitol.
- 1997 Jun;35(2):105-110.
- doi: 10.3347/kjp.1997.35.2.105
The gene encoding the 33 kDa piroplasm surface protein of Theileria sergenti isolated in Korea was cloned and the nucleotide sequence was determined by dideoxy chain termination method. The cloned... -
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- Molecules and their functions in autophagy
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Pyo JO, Nah J, Jung YK
- KMID: 1120125
- Exp Mol Med.
- 2012 Feb;44(2):73-80.
- doi: 10.3858/emm.2012.44.2.029
Autophagy is a self-degradation system of cellular components through an autophagosomal-lysosomal pathway. Over the last 15 yr, yeast genetic screens led to the identification of a number of genes involved... -
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- Brain site-specific proteome changes in aging-related dementia
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Manavalan , Mishra M, Feng L, Sze SK, Akatsu H, Heese K
- KMID: 2154258
- Exp Mol Med.
- 2013 Sep;45(9):e39.
This study is aimed at gaining insights into the brain site-specific proteomic senescence signature while comparing physiologically aged brains with aging-related dementia brains (for example, Alzheimer's disease (AD)). Our study... -
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- Genetic predisposition in nonalcoholic fatty liver disease
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Sookoian S, Pirola CJ
- KMID: 2412107
- Clin Mol Hepatol.
- 2017 Mar;23(1):1-12.
- doi: 10.3350/cmh.2016.0109
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease whose prevalence has reached global epidemic proportions. Although the disease is relatively benign in the early stages, when... -
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- Isolation, in vitro propagation, genetic analysis, and immunogenic characterization of an Ehrlichia canis strain from southeastern Brazil
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Alves RN, Rieck SE, Ueira-Vieira C, Labruna MB, Beletti ME
- KMID: 1784645
- J Vet Sci.
- 2014 Jun;15(2):241-248.
- doi: 10.4142/jvs.2014.15.2.241
Amplification of the 16S rRNA gene from a blood sample obtained from a dog in southeastern Brazil was used to confirm a naturally acquired Ehrlichia (E.) canis infection. Following isolation... -
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- Analysis of Single Nucleotide Polymorphism in Adolescent Idiopathic Scoliosis in Korea: For Personalized Treatment
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Moon ES, Kim HS, Sharma V, Park JO, Lee HM, Moon SH, Chong HS
- KMID: 1503917
- Yonsei Med J.
- 2013 Mar;54(2):500-509.
- doi: 10.3349/ymj.2013.54.2.500
PURPOSE: The incidence of adolescent idiopathic scoliosis (AIS) has rapidly increased, and with it, physician consultations and expenditures (about one and a half times) in the last 5 years. Recent... -
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- NRAMP1 gene polymorphisms in patients with rheumatoid arthritis in Koreans
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Yang YS, Kim SJ, Kim JW, Koh EM
- KMID: 1731240
- J Korean Med Sci.
- 2000 Feb;15(1):83-87.
- doi: 10.3346/jkms.2000.15.1.83
Natural resistance-associated macrophage protein 1 (Nramp1) is a genetic locus associated with innate resistance or susceptibility of murine hosts to infection with intracellular pathogens such as Salmonella, Leishmania and Mycobacterium.... -
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- Field Cancerization in Sporadic Colon Cancer
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Park SK, Song CS, Yang HJ, Jung YS, Choi KY, Koo DH, Kim KE, Jeong KU, Kim HO, Kim H, Chun HK, Park DI
- KMID: 2412075
- Gut Liver.
- 2016 Sep;10(5):773-780.
- doi: 10.5009/gnl15334
BACKGROUND/AIMS: Aberrant DNA methylation has a specific role in field cancerization. Certain molecular markers, including secreted frizzled-related protein 2 (SFRP2), tissue factor pathway inhibitor 2 (TFPI2), N-Myc downstream-regulated gene 4... -
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- Multi-transmembrane protein K15 of Kaposi's sarcoma-associated herpesvirus targets Lyn kinase in the membrane raft and induces NFAT/AP1 activities
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Cho NH, Choi YK, Choi JK
- KMID: 1104811
- Exp Mol Med.
- 2008 Oct;40(5):565-573.
- doi: 10.3858/emm.2008.40.5.565
Viral proteins of gamma-2 herpesviruses, such as LMP2A of Epstein Barr virus (EBV) and Tip of herpesvirus saimiri (HVS) dysregulate lymphocyte signaling by interacting with Src family kinases. K15 open... -
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- Identification of Proteins That Interact with Podocin Using the Yeast 2-Hybrid System
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Park SJ, Lee BH, Kim DJ
- KMID: 2396072
- Yonsei Med J.
- 2009 Apr;50(2):273-279.
PURPOSE: As a membrane protein at the insertion site of the slit diaphragm (SD) complex in podocyte foot processes, podocin has been reported to act as a scaffolding protein required... -
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- A Population-Based Genomic Study of Inherited Metabolic Diseases Detected Through Newborn Screening
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Park KJ, Park S, Lee E, Park JH, Park JH, Park HD, Lee SY, Kim JW
- KMID: 2373595
- Ann Lab Med.
- 2016 Nov;36(6):561-572.
- doi: 10.3343/alm.2016.36.6.561
BACKGROUND: A newborn screening (NBS) program has been utilized to detect asymptomatic newborns with inherited metabolic diseases (IMDs). There have been some bottlenecks such as false-positives and imprecision in the... -
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- Analysis of antigenic domain of GST fused major surface protein (p30) fragments of Toxoplasma gondii
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Nam HW, Im KS, Baek EJ, Choi WY, Cho SY
- KMID: 658223
- Korean J Parasitol.
- 1996 Jun;34(2):135-141.
- doi: 10.3347/kjp.1996.34.2.135
Antigenic domain of major surface protein (p30) of Toxoplasma gondii was analyzed after polymerase chain reaction (PCR) of its gene fragments. Hydrophilic or hydrophobic moiety of amino acid sequences were... -
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- Radiologic and Pathologic Findings of a Follicular Variant of Papillary Thyroid Cancer with Extensive Stromal Fat: A Case Report
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Choi JW, Kim TH, Roh HG, Moon WJ, Lee SH, Hwang TS, Park KS
- KMID: 2344291
- Korean J Radiol.
- 2015 Dec;16(6):1349-1352.
- doi: 10.3348/kjr.2015.16.6.1349
Thyroid cancer may have small adipose structures detected by microscopy. However, there are no reports of thyroid cancer with gross fat evaluated by radiological methods. We reported a case of... -
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- Persistence of Orientia tsutsugamushi in Humans
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Chung MH, Lee JS, Baek JH, Kim M, Kang JS
- KMID: 1792991
- J Korean Med Sci.
- 2012 Mar;27(3):231-235.
- doi: 10.3346/jkms.2012.27.3.231
We investigated the persistence of viable Orientia tsutsugamushi in patients who had recovered from scrub typhus. Blood specimens were available from six patients with scrub typhus who were at 1... -
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- Leukotriene-related Gene Polymorphisms in Patients with Aspirin-intolerant Urticaria and Aspirin-intolerant Asthma: Differing Contributions of ALOX5 Polymorphism in Korean Population
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Kim SH, Choi JH, Holloway J, Suh CH, Nahm DH, Ha EH, Park CS, Park HS
- KMID: 2157738
- J Korean Med Sci.
- 2005 Dec;20(6):926-931.
- doi: 10.3346/jkms.2005.20.6.926
The pathogenesis of aspirin (acetylsalicylic acid, ASA)-intolerant urticaria (AIU) is still poorly understood but it has recently been suggested that it is associated with the overproduction of leukotriene (LT). This... -
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- Identification of a Novel Deletion Region in 3q29 Microdeletion Syndrome by Oligonucleotide Array Comparative Genomic Hybridization
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Seo EJ, Jun KR, Yoo HW, Yoo HK, Lee JO
- KMID: 1096822
- Korean J Lab Med.
- 2010 Feb;30(1):70-75.
- doi: 10.3343/kjlm.2010.30.1.70
BACKGROUND: The 3q29 microdeletion syndrome is a genomic disorder characterized by mental retardation, developmental delay, microcephaly, and slight facial dysmorphism. In most cases, the microdeletion spans a 1.6-Mb region between... -
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- Differential Immunohistological Features of Inflammatory Myopathies and Dysferlinopathy
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Choi JH, Park YE, Kim SI, Kim JI, Lee CH, Park KH, Kim DS
- KMID: 1783127
- J Korean Med Sci.
- 2009 Dec;24(6):1015-1023.
- doi: 10.3346/jkms.2009.24.6.1015
This study was performed in order to characterize the types of the infiltrating cells, and the expression profiles of major histocompatibility complex (MHC) class I and membrane attack complex (MAC)... -
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- Protective effects of recombinant Brucella abortus Omp28 against infection with a virulent strain of Brucella abortus 544 in mice
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Lim JJ, Kim DH, Lee JJ, Kim DG, Min W, Lee HJ, Rhee MH, Kim S
- KMID: 1389768
- J Vet Sci.
- 2012 Sep;13(3):287-292.
- doi: 10.4142/jvs.2012.13.3.287
The outer membrane proteins (OMPs) of Brucella (B.) abortus have been extensively studied, but their immunogenicity and protective ability against B. abortus infection are still unclear. In the present study,... -
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- Nonalcoholic Fatty Liver Disease
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Ko JS
- KMID: 1775872
- Korean J Gastroenterol.
- 2010 Jul;56(1):6-14.
- doi: 10.4166/kjg.2010.56.1.6
Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide, and is commonly associated with obesity. The spectrum of NAFLD ranges from simple steatosis to nonalcoholic steatohepatitis (NASH)... -
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- Evaluation of serotyping using monoclonal antibodies and PCR-RFLP for Chlamydia trachomatis serotype identification
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Choi TY, Kim DA, Seo YH
- KMID: 1066488
- J Korean Med Sci.
- 2001 Feb;16(1):15-19.
- doi: 10.3346/jkms.2001.16.1.15
We compared genotyping by restriction fragment length polymorphism (RFLP) analysis of the amplified omp1 gene with serotyping by dot enzyme-linked immunosorbent assay (dot-ELISA) to determine the suitability of RFLP analysis... -
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