- Lipid rafts are important for the association of RANK and TRAF6
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Ha H, Kwak HB, Le SW, Kim HH, Lee ZH
- KMID: 1109317
- Exp Mol Med.
- 2003 Aug;35(4):279-284.
Rafts, cholesterol- and sphingolipid-rich membrane microdomains, have been shown to play an important role in immune cell activation. More recently rafts were implicated in the signal transduction by members of... -
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- Effect of Irradiation on Microparticles in Red Blood Cell Concentrates
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Cho CH, Yun SG, Koh YE, Lim CS
- KMID: 2373557
- Ann Lab Med.
- 2016 Jul;36(4):362-366.
- doi: 10.3343/alm.2016.36.4.362
Changes in microparticles (MP) from red blood cell (RBC) concentrates in the context of irradiation have not been investigated. The aim of this study was to evaluate how irradiation affects... -
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- LRIG1 Enhances Chemosensitivity by Modulating BCL-2 Expression and Receptor Tyrosine Kinase Signaling in Glioma Cells
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Guo Z, Chen Q, Liu B, Tian D, Zhang S, Li M
- KMID: 1799481
- Yonsei Med J.
- 2014 Sep;55(5):1196-1205.
- doi: 10.3349/ymj.2014.55.5.1196
PURPOSE: Leucine-rich repeats and immunoglobulin-like domains 1 (LRIG1) are an inhibitor of receptor tyrosine kinases (RTKs) that was discovered in recent years, and many studies showed that LRIG1 is a... -
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- Rhamnogalacturonan II is a Toll-like receptor 4 agonist that inhibits tumor growth by activating dendritic cell-mediated CD8+ T cells
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Park SN, Noh KT, Jeong YI, Jung ID, Kang HK, Cha GS, Lee SJ, Seo JK, Kang DH, Hwang TH, Lee EK, Kwon B, Park YM
- KMID: 2154227
- Exp Mol Med.
- 2013 Feb;45(2):e8.
We evaluated the effectiveness of rhamnogalacturonan II (RG-II)-stimulated bone marrow-derived dendritic cells (BMDCs) vaccination on the induction of antitumor immunity in a mouse lymphoma model using EG7-lymphoma cells expressing ovalbumin... -
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- Metabolic loading of guanosine induces chondrocyte apoptosis via the Fas pathway
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Kim DJ, Chung JH, Ryu EK, Rhim JH, Ryu YS, Park SH, Kim KT, Kang HS, Chung HK, Park SC
- KMID: 1110124
- Exp Mol Med.
- 2006 Aug;38(4):401-407.
Although the apoptosis of chondrocytes plays an important role in endochondral ossification, its mechanism has not been elucidated. In this study, we show that guanosine induces chondrocyte apoptosis based on... -
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- Expression of CD40 and Apoptosis Related Molecules in Autoimmune Thyroid Diseases
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Kie JH, Cho MS, Yang WI
- KMID: 1728870
- Yonsei Med J.
- 2001 Oct;42(5):488-496.
- doi: 10.3349/ymj.2001.42.5.488
Apoptosis is responsible for the loss of thyrocytes in autoimmune thyroiditis. Recent investigations into the pathogenesis of apoptosis have revealed that the important roles of suicide molecules expression on both... -
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- Activation of caspase-8 in 3-deazaadenosine-induced apoptosis of U-937 cells occurs downstream of caspase-3 and caspase-9 without Fas receptor-ligand interaction
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Chae YJ, Kim HS, Rhim HS, Kim BE, Jeong SW, Kim IK
- KMID: 1457543
- Exp Mol Med.
- 2001 Dec;33(4):284-292.
3-Deazaadenosine (DZA), a cellular methylation blocker was reported to induce the caspase-3-like activities-dependent apoptosis in U-937 cells. In this study, we analyzed the activation pathway of the caspase cascade involved... -
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