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Coincidence of Dermal Melanocyte Hamartoma and Becker's Nevus in a Patient with Neurofibromatosis Type 1

Kim YJ, Choi ME, Lee MW, Choi JH, Chang SE

  • KMID: 2470219
  • Korean J Dermatol.
  • 2019 Dec;57(10):632-634.
Dermal melanocytosis is characterized by an increased number of ovoid to elongated melanocytes situated between collagen fibers in the dermis, including blue nevus, Mongolian spots, nevus of Ota and Ito...
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Adipose-Derived Stem Cell Coculturing Stimulates Integrin-Mediated Extracellular Matrix Adhesion of Melanocytes by Upregulating Growth Factors

Kim H, Yi N, Do BR, Lee AY

Coculture with adipose-derived stem cells (ADSCs) can stimulate proliferation and migration of melanocytes. To enhance outcomes of skin disorders caused by melanocyte loss or death, mixed transplantation with ADSCs has...
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Some Becker's Nevus Melanocytes Remain Alive after Treatment with Q-Switched Alexandrite Laser

Jung HJ, Moon SY, Sohn MY, Jang YH, Lee SJ, Kim DW, Lee WJ

No abstract available.
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Pimecrolimus increases the melanogenesis and migration of melanocytes in vitro

Xu P, Chen J, Tan C, Lai RS, Min ZS

Vitiligo is an intriguing depigmentary disorder and is notoriously difficult to be treated. The ultimate goal of vitiligo treatment is to replenish the lost melanocytes by immigration from hair follicle...
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Clinicopathological Features and Immunohistochemical Alterations of Keratinocyte Proliferation, Melanocyte Density, Smooth Muscle Hyperplasia and Nerve Fiber Distribution in Becker's Nevus

Sheng P, Cheng YL, Cai CC, Guo WJ, Zhou Y, Shi G, Fan YM

BACKGROUND: Although Becker's nevus (BN) is a relatively common disease, the systematic studies of clinicopathological and immunohistochemical results are poorly reported. OBJECTIVE: To investigate the clinicopathological features and immunohistochemical alterations of...
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Pigmentation Effect of Electromagnetic Fields at Various Intensities to Melanocytes

Cho SE, Kim YM, Kang KH, Kim SC, Park JK, Seo YK

Melanogenesis is the biological process that results in the synthesis of skin pigment of melanin and it has various functions in living systems and is synthesized by the melanosome within...
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Effect of MITF-M and MITF-A Overexpression on the Dendrtic Formation in Melanocytes

Jo IS, Sohn KC, Kim CD, Lee YH

The microphthalmia-associated transcription factor (MITF), has been described as the master regulator of the basic helix-loop-helix leucine zipper family, involves melanogenesis in melanocytes. MITF consists of at least six isoforms,...
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Early Involvement of Hair Melanocytes Prior to Epidermal Melanocytes in the Progress of Halo Nevus

Shin S, Oh SH

  • KMID: 2350798
  • Korean J Dermatol.
  • 2016 Feb;54(2):151-153.
No abstract available.
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Modulation of Melanogenesis by Heme Oxygenase-1 via p53 in Normal Human Melanocytes

Lim HS, Jin S, Yun SJ

As a key regulator of melanogenesis, p53 controls microphthalmia-associated transcription factor (MITF) and tyrosinase expression. The anti-oxidant enzyme heme oxygenase-1 (HO-1) is induced by various forms of cellular stress and...
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Changes in Melanin and Melanocytes in Mottled Hypopigmentation after Low-Fluence 1,064-nm Q-Switched Nd:YAG Laser Treatment for Melasma

Jang YH, Park JY, Park YJ, Kang HY

No abstract available.
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Possible Existence of Melanocytes or Melanoblasts in Human Sebaceous Glands

Jang YH, Kim SL, Lee JS, Kwon KY, Lee SJ, Kim DW, Lee WJ

BACKGROUND: Melanocytes are present in both basal epidermis and hair follicles. Melanocyte stem cells have been found in hair follicle bulge. During embryogenesis, the outer cells of the bulge differentiate...
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Adipose-Derived Stem Cells Improve Efficacy of Melanocyte Transplantation in Animal Skin

Lim WS, Kim CH, Kim JY, Do BR, Kim EJ, Lee AY

  • KMID: 2170627
  • Biomol Ther.
  • 2014 Jul;22(4):328-333.
Vitiligo is a pigmentary disorder induced by a loss of melanocytes. In addition to replacement of pure melanocytes, cocultures of melanocytes with keratinocytes have been used to improve the repigmentation...
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The Effects of Keratinocyte-derived Factors Involved in Transforming the Morphologies of Melanocyte and in Translocating Melanosomes to Keratinocyte

Yoon YH, Kim JY, Song IH, Sung EG

  • KMID: 2224463
  • Korean J Anat.
  • 2007 Sep;40(3):235-241.
Keratinocyte-derived factors are involved in regulating the proliferation, differentiation or melanogenesis of melanocytes. To investigate the effects of keratinocyte-derived factors on the skin pigmentation, human melanocytes and keratinocytes were cultivated...
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Effect of Trans-4-Aminomethylcyclohexanecarboxylic Acid on the Proliferation and Melanization in Cultured Normal Human Melanocytes

Seo SJ, Cho SH, Cho WI, Jung MS, Ro SW, Kim MN, Hong CK

  • KMID: 2352827
  • Ann Dermatol.
  • 2007 Jun;19(2):60-67.
BACKGROUND: Trans-4-aminomethylcyclohexanecarboxylic acid (tranexamic acid) has recently been reported to inhibit prostaglandin synthesis and hinder the pigmentation caused after UV radiation. OBJECTIVE: we evaluated the influence of tranexamic acid on...
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The Effects of Tacrolimus on Keratinocytes and Melanocytes of Vitiligo

Kim HJ, Sung HC, Park KD, Na GY, Lee WJ, Lee SJ, Kim DW

  • KMID: 2248954
  • Korean J Dermatol.
  • 2006 Jun;44(6):708-713.
BACKGROUND: Vitiligo is caused by the destruction of melanocytes, however the precise mechanism is still not known. Recently, abnormalities of both humoral and cell-mediated immunity have been documented in patients...
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Expression of Human Melanocyte Markers in PMA-containing Medium and Physiologic Mitogen-containing Medium

Yoon TJ, Kim KT, Kim KH, Lee JW, Lee MH

  • KMID: 2248994
  • Korean J Dermatol.
  • 2006 May;44(5):579-585.
BACKGROUND: There are many growth media for cultivation of human melanocytes (MGM), depending on the supplements added, and the growth of cells is closely related to these components. To understand...
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A Case of Dermal Melanocyte Hamartoma Treated with Q-switched Nd-YAG Laser

Kim JE, Ahn JY, Seo SJ, Hong CK

  • KMID: 2302651
  • Korean J Dermatol.
  • 2005 Apr;43(4):522-524.
Dermal melanocytosis is characterized by the presence of ectopic melanocytes in the dermis. There are several clinical forms, such as blue nevus, mongolian spot, nevus of Ota, nevus of Ito...
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Numerical Changes of Melanocytes in Artificial Epidermis Reconstructed by Keratinocytes and Melanocytes Coculture

Song IH

  • KMID: 2030763
  • Korean J Anat.
  • 2004 Apr;37(2):199-207.
To follow up the change of melanocytes to keratinocytes ratio in stratified epidermis reconstructed by mixed culture of these cells, the author investigated the ratio of melanocyte to keratinocyte in...
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Identification of UVB Effects on Gene Expressed by Normal Human Melanocytes

Kim HS, Park HH, Lee MH

  • KMID: 1977852
  • Korean J Dermatol.
  • 2003 Dec;41(12):1597-1602.
BACKGROUND: Irradiation of the skin with ultraviolet rays result in alterations of immune response as well as melanogenesis and melanocarcinogenensis. These effects are largely mediated by soluble mediators released from...
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SM709, Ingredient of Antimelanogenic Bamboo Extract, Blocks Endothelin-1-induced [Ca2+]i Increase in Human Melanocytes

Kim SH, Lee KM, Kim HS, Lee GS, Jeon BH, Kim KJ, Park JB

  • KMID: 1607515
  • Korean J Physiol Pharmacol.
  • 2003 Dec;7(6):311-316.
Endothelins secreted from keratinocytes are intrinsic mitogens and melanogens of human melanocytes in UVB-induced hyperpigmentation. To elucidate the cellular mechanism of antimelanogenic activity of bamboo extract, the effects of three...
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