Korean J Dermatol.
1997 Jun;35(3):571-574.
Microscopic Findings of Cultured Human Melanocytes from a Vitiligo Subject
Abstract
- Vitiligo is an acquired systemic disease of the skin characterized by circumscribed patches of complete pigment loss due to destruction of melanocytes. A 28-year old male patient presented with generalized depigmented patchs. We performed microscopic studies of cultured melanocytes from this patient and compared them with those of normal neonatal foreskin. Phase contrast microscopic findings revealed no difference between the two groups of melanocytes, but transmission electron microscopic findings showed dilated circular rough endoplasmic reticulum in cultured melanocytes from our vitiligo patient. We could observe the innate cellular structural aberration of melanocytes from the vitiligo subject.
Keyword
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Culture of melanocytes obtained from normal and vitiligo subjects
- Two Cases of Vitiligo Developed on the Persisting Dermal Melanocytosis: Is There a Difference between Epidermal Melanocytes and Dermal Melanocytes?
- The Effects of Tacrolimus on Keratinocytes and Melanocytes of Vitiligo
- Effect of suction blister fluid and IFN-gamma on HLA-A,B,C and HLA-DR espression in cultures human melanocytes
- Understanding of Pathomechanisms and Clinical Practice for Vitiligo
