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Imaging Spectrum and Pitfalls of 11C-Methionine Positron Emission Tomography in a Series of Patients with Intracranial Lesions

Ito K, Matsuda H, Kubota K

11C-methionine (Met) positron emission tomography (PET) is one of the most commonly used PET tracers for evaluating brain tumors. However, few reports have described tips and pitfalls of 11C-Met PET...
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Relationship between Autistic Spectrum Trait and Regional Cerebral Blood Flow in Healthy Male Subjects

Ota M, Matsuo J, Sato N, Teraishi T, Hori H, Hattori K, Kamio Y, Maikusa N, Matsuda H, Kunugi H

OBJECTIVE: Autistic spectrum traits are postulated to lie on a continuum that extends between individuals with autism and individuals with typical development. The present study was carried out to investigate...
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A Single Intraperitoneal Injection of Endotoxin Changes Glial Cells in Rats as Revealed by Positron Emission Tomography Using [¹¹C]PK11195

Ota M, Ogura J, Ogawa S, Kato K, Matsuda H, Kunugi H

PURPOSE: Intracranial administration of lipopolysaccharide (LPS) is known to elicit a rapid innate immune response, activate glial cells in the brain, and induce depression-like behavior. However, no study has focused...
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Benefits of hesperidin in central nervous system disorders: a review

Kim J, Wie MB, Ahn M, Tanaka A, Matsuda H, Shin T

Citrus species contain significant amounts of flavonoids that possess antioxidant activities; furthermore, dietary citrus is not associated with adverse effects or cytotoxicity in healthy individuals. Hesperidin, which is an abundant...
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Gene Expression Profile of Olfactory Transduction Signaling in an Animal Model of Human Multiple Sclerosis

Kim J, Ahn M, Choi Y, Ekanayake , Park CM, Moon C, Jung K, Tanaka A, Matsuda H, Shin T

Olfactory dysfunction occurs in multiple sclerosis in humans, as well as in an animal model of experimental autoimmune encephalomyelitis (EAE). The aim of this study was to analyze differentially expressed...
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Relationship Between Vitamin D Status and Brain Perfusion in Neuropsychiatric Lupus

Sultana N, Sarkar AK, Matsuda H, Ihsan MA, Haq SA, Arefin MS, Islam SN

Purpose Neuropsychiatric manifestation of lupus (NPSLE) is related with vitamin D (vit-D) deficiency which is possibly amenable to supplementation. This study was done to explore link of serum vit-D level...
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Attenuation of Experimental Autoimmune Uveitis in Lewis Rats by Betaine

Choi Y, Jung K, Kim HJ, Chun J, Ahn M, Jee Y, Ko HJ, Moon C, Matsuda H, Tanaka A, Kim J, Shin T

  • KMID: 2519892
  • Exp Neurobiol.
  • 2021 Aug;30(4):308-317.
  • doi: 10.5607/en21011
Experimental autoimmune uveitis (EAU) is an animal model of human autoimmune uveitis that is characterized by the infiltration of autoimmune T cells with concurrent increases in pro-inflammatory cytokines and reactive...
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Influence of Signal Intensity Non-Uniformity on Brain Volumetry Using an Atlas-Based Method

Goto M, Abe O, Miyati T, Kabasawa H, Takao H, Hayashi N, Kurosu T, Iwatsubo T, Yamashita , Matsuda H, Mori H, Kunimatsu , Aoki S, Ino K, Yano K, Ohtomo K, Japanese Alzheimer's Disease Neuroimaging Initiative

OBJECTIVE: Many studies have reported pre-processing effects for brain volumetry; however, no study has investigated whether non-parametric non-uniform intensity normalization (N3) correction processing results in reduced system dependency when using...
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