- The Differential expression of matrix metalloproteinase and their tissue inhibitors in myometrium and leiomyoma
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Yoo EH, Whang EM, Yu HK, Kim SB
- KMID: 2261615
- Korean J Obstet Gynecol.
- 1999 Dec;42(12):2806-2814.
OBJECTIVES: To determine the level of mRNA expression of various members of the matrix metalloproteinase and tissue inhibitors in uterine leiomyoma compared with unaffected myometrium. Materials & Method: 30 cases of... -
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- Effects of Hepatocyte Growth Factor on Collagen Synthesis and Matrix Metalloproteinase Production in Keloids
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Lee WJ, Park SE, Rah DK
- KMID: 1777848
- J Korean Med Sci.
- 2011 Aug;26(8):1081-1086.
- doi: 10.3346/jkms.2011.26.8.1081
Keloids are pathologic proliferations of the dermal layer of the skin resulting from excessive collagen production and deposition. Hepatocyte growth factor (HGF) increases the expression of matrix metalloproteinase (MMP)-1 and... -
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- Matrix Metalloproteinase-3 Gene Polymorphism is Associated with Coronary Artery Calcification Scores in Patients with Type 2 Diabetes Mellitus
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Kim SW, Cho EH
- KMID: 2298068
- Korean Diabetes J.
- 2009 Apr;33(2):113-123.
- doi: 10.4093/kdj.2009.33.2.113
BACKGROUND: Matrix metalloproteinase-3 (MMP-3) is expressed in human coronary atherosclerotic lesions and is known to be involved in the degradation of plaque. This study examines the association of MMP-3 gene... -
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- Matrix Metallopeptidase 3 Polymorphisms: Emerging genetic Markers in Human Breast Cancer Metastasis
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Suhaimi SA, Chan SC, Rosli R
- KMID: 2470877
- J Breast Cancer.
- 2020 Feb;23(1):1-9.
- doi: 10.4048/jbc.2020.23.e17
Matrix metallopeptidase 3 or MMP3, is a zinc-dependent proteolytic enzyme that is involved in various physiological processes via modification of the extracellular matrix. In particular, its over-expression has been associated... -
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- Vitamin D Receptor Gene, Matrix Metalloproteinase 3 Polymorphisms and the Risk of Intervertebral Disc Degeneration Susceptibility: Meta-Analysis
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Nong L, Huang Y, Zhao S, Xu N
- KMID: 2354825
- Asian Spine J.
- 2016 Oct;10(5):964-971.
- doi: 10.4184/asj.2016.10.5.964
Several studies have evaluated the association between vitamin D receptor, matrix metalloproteinase 3 (MMP-3) polymorphisms and the risk of intervertebral disc degeneration susceptibility. The findings were inconsistent. This meta-analysis aimed... -
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- Stromelysin-3 Expression in Squamous Intraepithelial Lesions and Invasive Squamous Cell Carcinoma of the Uterine Cervix
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Choi YD, Park EJ, Nam JH, Park CS
- KMID: 1725938
- Korean J Pathol.
- 2002 Dec;36(6):389-393.
BACKGROUND: Matrix metalloproteinase (MMP) plays an important role in the invasion and metastasis of epithelial neoplasms. Currently, detected stromelysin-3 (ST-3) (MMP-11) is thought to be associated with invasiveness in epithelial... -
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- Expression of Matrix-Metalloproteinase-2, Urokinase-Type Plasminogen Activator and Plasminogen Activator Inhibitor-1 in Invasion Mode and Lymph Node Metastasis of Laryngeal Squamous Cell Carcinoma
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Jin SM, Lee SH, Choi G, Choi JO
- KMID: 2274480
- Korean J Otolaryngol-Head Neck Surg.
- 1998 Sep;41(9):1169-1173.
BACKGROUND AND OBJECTIVES: Metastatic process of carcinoma cells involves dissolution of tumor matrix and penetration of the basement membrane (BM) which involves the active proteolysis of type IV collagen, proteoglycan,... -
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- Adenovirus Vector-mediated Gene Transfer into Human Trabecular Cell
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Kee C, Son S, Kim T, Lim J
- KMID: 2147629
- J Korean Ophthalmol Soc.
- 1999 May;40(5):1311-1317.
We attempted to observe the expression of stromelysin, which regulates the extracellular matrix of trabecular meshwork and is one of the family of the matrix metalloproteinases, in the trabecular cells... -
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- In Vitro Effects of Bupivacaine in Cell Proliferation and Matrix Metalloproteinase of Cultured Fibroblast Like Synoviocytes from Rheumatoid Arthritis
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Han TH, Jang HJ
- KMID: 2335875
- J Korean Pain Soc.
- 2000 Jun;13(1):1-7.
BACKGROUND: Intraarticular local anesthetic injection has been therapeutically applied for pain control in various arthritis patients. However, little physiologic effects of local anesthetics on their tissue were known. This study was conducted... -
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- The Increased Expression of Matrix Metalloproteinases Associated with Elastin Degradation and Fibrosis of the Ligamentum Flavum in Patients with Lumbar Spinal Stenosis
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Park JB, Kong CG, Suhl KH, Chang ED, Riew KD
- KMID: 1122637
- Clin Orthop Surg.
- 2009 Jun;1(2):81-89.
- doi: 10.4055/cios.2009.1.2.81
BACKGROUND: One of the characteristics of spinal stenosis is elastin degradation and fibrosis of the extracellular matrix of the ligamentum flavum. However, there have been no investigations to determine which... -
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- Matrix Metalloproteinase-3 Genotypes Influence Recovery from Hepatitis B Virus Infection
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Cheong JY, Cho SW, Lee JA, Lee KJ, Wang HJ, Lee JE, Kim JH
- KMID: 1786846
- J Korean Med Sci.
- 2008 Feb;23(1):61-65.
- doi: 10.3346/jkms.2008.23.1.61
The reasons for the viral persistence of hepatitis B virus (HBV) infection are unknown, but are probably related to host immune factors. Several matrix metalloproteinases (MMPs) can regulate an inflammatory... -
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- The Production of Interleukin - 1 and Stromelysin in the Cultured Intervertebral Disc Cells of Rabbit
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Kim DJ
- KMID: 2336071
- J Korean Orthop Assoc.
- 1998 Jun;33(3):858-867.
The cells of anulus fibrosus(AF) and nucleus pulposus(NP) of intervertebral disc are thought to be different in their cell components and in their roles during degeneration. The purpose of this... -
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- Stromelysin Gene Expression in Rat Eye Mediated by the Adenovirus Vector
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Kang S, Hur WH, Kee C
- KMID: 2125134
- J Korean Ophthalmol Soc.
- 2001 Feb;42(2):378-385.
The purpose of this study is to evaluate the eligibility of gene therapy in treating glaucoma by constructing a replication deficient recombinant adenovirus carrying cDNA of stromelysin and by observing... -
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- Stromelysin Gene Promoter 5A/6A Polymorphism and Risk of Restenosis after Coronary Angioplasty
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Lee KH, Chae IH, Cho HJ, Choi SY, Ju JR, Park SH, Sohn DW, Oh BH, Lee MM, Park YB, Choi YS, Lee YW
- KMID: 2227300
- Korean Circ J.
- 2001 Sep;31(9):955-960.
- doi: 10.4070/kcj.2001.31.9.955
BACKGROUND: Remodeling of extracellular matrix is one of the main mechanism of restenosis that is the major limitation of percutaneous coronary angioplasty. Stromelysin is one of the matrix metalloproteinase, which... -
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- In Vitro Effects of Ultrasound on Fibroblast Like Synoviocytes from Rheumatoid Arthritis
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Kim HS, Han TR, Koh EM
- KMID: 2174654
- J Korean Acad Rehabil Med.
- 2001 Feb;25(1):140-149.
OBJECTIVE: Ultrasound has been therapeutically applied for pain control in rheumatoid arthritis although little physiologic effects of sonication on rheumatoid tissue were known. This investigation was conducted to determine the... -
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- Cordycepin inhibits UVB-induced matrix metalloproteinase expression by suppressing the NF-kappa B pathway in human dermal fibroblasts
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Lee YR, Noh EM, Jeong EY, Yun SK, Jeong YJ, Kim JH, Kwon KB, Kim BS, Lee SH, Park CS, Kim JS
- KMID: 1119320
- Exp Mol Med.
- 2009 Aug;41(8):548-554.
- doi: 10.3858/emm.2009.41.8.060
Cordycepin (3'-deoxyadenosine) has been shown to exhibit many pharmacological activities, including anti-cancer, anti-inflammatory, and anti-infection activities. However, the anti-skin photoaging effects of cordycepin have not yet been reported. In the... -
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- Expression of Wild Type and Truncated Myocilins in Trabecular Meshwork Cells: their Subcellular Localization
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Hur WH, Kee CW
- KMID: 2125618
- J Korean Ophthalmol Soc.
- 2003 Apr;44(4):955-964.
PURPOSE: To investigate subcellular localizations of wild type myocilin and trunctated (Q368X) myocilin in cultured human trabecular meshwork (TM) cells. METHODS: GFP and GFP tagged truncated myocilin, full-length myocilin, and... -
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- Inhalation Therapy of Calcitonin Relieves Osteoarthritis of the Knee
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Armagan O, Serin DK, Calisir C, Dokumacioglu A, Ozgen M, Oner S, Alatas O
- KMID: 2157954
- J Korean Med Sci.
- 2012 Nov;27(11):1405-1410.
- doi: 10.3346/jkms.2012.27.11.1405
This study was conducted to determine if nasal salmon calcitonin has additional beneficial effects on clinical symptoms, serum NO, IL-1beta, matrix metalloproteinase 3, urinary C-terminal telopeptide type II collagen (CTX-II)... -
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- Effects of adenovirus-mediated bFGF, IL-1Ra and IGF-1 gene transfer on human osteoarthritic chondrocytes and osteoarthritis in rabbits
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Chen B, Qin J, Wang H, Magdalou J, Chen L
- KMID: 964663
- Exp Mol Med.
- 2010 Oct;42(10):684-695.
- doi: 10.3858/emm.2010.42.10.067
The study investigated the effects of adenovirus-mediated gene transfection of basic fibroblast growth factor (bFGF), bFGF combined with interleukin-1 receptor antagonist protein (IL-Ra) and/or insulin-like growth factor-1 (IGF-1) both in... -
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- Microglia, major player in the brain inflammation: their roles in the pathogenesis of Parkinson's disease
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Kim YS, Joh TH
- KMID: 1110117
- Exp Mol Med.
- 2006 Aug;38(4):333-347.
Inflammation, a self-defensive reaction against various pathogenic stimuli, may become harmful self-damaging process. Increasing evidence has linked chronic inflammation to a number of neurodegenerative disorders including Alzheimer's disease (AD), Parkinson's... -
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