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Extensive acute lung injury following limited thoracic irradiation: radiologic findings in three patients

Hwang JH, Lee KS, Song KS, Kim H, Kwon OJ, Lim TH, Ahn YC, Choo IW

The aim of our study was to describe the radiologic findings of extensive acute lung injury associated with limited thoracic irradiation. Limited thoracic irradiation occasionally results in acute lung injury....
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Rapidly Growing Interval Colon Cancer

Kim JH, Park MI

No abstract available.
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Management consideration in nonpulmonary visceral metastatic seminoma of testis

Park DS, Prow DM, Amato RJ, Logothetis CJ

To develop a more appropriate therapeutic strategy for treatment of nonpulmonary visceral metastatic testicular seminoma based on the International Germ Cell Consensus Classification, we reviewed the medical records of patients...
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Four cases of therapy-related leukemia

Hur M, Lee DS, Shin HY, Ahn HS, Kim BK, Cho HI

Combination chemotherapy and radiation therapy have contributed to the successful treatment of various cancer patients. But the development of second malignancies is an inevitable complication of long-term cytotoxic treatment. The most serious and...
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Clinical Characteristics of Pulmonary Embolism with Underlying Malignancy

Lee JE, Kim HR, Lee SM, Yim JJ, Yoo CG, Kim YW, Han SK, Shim YS, Yang SC

BACKGROUND/AIMS: The risk of venous thromboembolism (VTE), which encompasses deep vein thrombosis and pulmonary embolism (PE), increases in patients with cancer. Anticancer treatment is also associated with an increased risk...
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Orbital Metastatic Angiosarcoma

Hassane S, Fouad E, Said I, Karim R, Asmae N, Houcine C, Abdelbar O

We report a case of a 48-year-old man who developed metastatic angiosarcoma in her left orbit. A 48-year-old man was first sent to us for a check up of proptosis...
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The relationship between cisplatin-induced apoptosis and p53, bcl-2 and bax expression in human lung cancer cells

Han JY, Chung YJ, Park SW, Kim JS, Rhyu MG, Kim HK, Lee KS

  • KMID: 759083
  • Korean J Intern Med.
  • 1999 Jan;14(1):42-52.
OBJECTIVES: Given the roles of bcl-2, bax and p53 in apoptosis, we investigated the effect of their expression on the response to cisplatin in order to understand the...
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Enhanced Chemotherapeutic Drug Delivery to Tumor Tissue by High Intensity Focused Ultrasound

Jung JT, Lee DH, Hwang JH

  • KMID: 783156
  • Korean J Gastroenterol.
  • 2009 Apr;53(4):216-220.
Cancer is the first leading cause of death in Korea. Systemic chemotherapy is currently the standard treatment for a wide variety of cancers; however, in the majority of cases, cure...
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Influence of Methylenetetrahydrofolate Reductase C677T Polymorphism on the Risk of Lung Cancer and the Clinical Response to Platinum-Based Chemotherapy for Advanced Non-Small Cell Lung Cancer: An Updated Meta-Analysis

Zhu N, Gong Y, He J, Xia J, Chen X

PURPOSE: Methylenetetrahydrofolate reductase (MTHFR) has been implicated in lung cancer risk and response to platinum-based chemotherapy in advanced non-small cell lung cancer (NSCLC). However, the results are controversial. We performed...
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Effects of allyl sulfur compounds and garlic extract on the expression of Bcl-2, Bax, and p53 in non small cell lung cancer cell lines

Hong YS, Ham YA, Choi JH, Kim JG

  • KMID: 755076
  • Exp Mol Med.
  • 2000 Sep;32(3):127-134.
Allyl sulfur compounds play a major role in the chemoprevention against carcinogenesis. The present study compared the antiproliferative effects of diallyl sulfide (DAS), diallyl disulfide (DADS) and garlic...
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A Case of Pseudomenbranous Colitis after Paclitaxel and Carboplatin Chemotherapy

Yang SW, Moon W

Antibiotics-associated pseudomembranous colitis is well documented and caused by abnormal overgrowth of toxin producing Clostridium difficile colonizing the large bowel of patients undergoing antibiotic therapy. Administration of chemotherapeutic agents is...
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Bi-weekly Chemotherapy of Paclitaxel and Cisplatin in Patients with Metastatic or Recurrent Esophageal Cancer

Cho SH, Chung IJ, Song SY, Yang DH, Byun JR, Kim YK, Lee JJ, Na KJ, Kim HJ

Although various combinations of chemotherapy regimens have been tried for patients with esophageal cancer, their duration of survival is extremely poor. In this study, we investigated the safety and clinical...
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Post-Progression Survival in Patients with Non-Small Cell Lung Cancer with Clinically Acquired Resistance to Gefitinib

Kim H, Yun T, Lee YJ, Han JY, Kim HT, Lee GK

Most patients with tyrosine kinase inhibitor (TKI)-sensitive non-small cell lung cancer (NSCLC) eventually develop acquired resistance to TKIs. Factors that affect TKI-sensitive patient survival after progression during TKI treatment remain...
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The Role of Pharmacoethnicity in the Development of Cytotoxic and Molecular Targeted Drugs in Oncology

Saijo N

The effective and toxic ranges of anticancer drugs are very narrow and, in some cases, inverted. Thus determination of the most appropriate dosage and schedule of administration is crucial for...
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Liposomal honokiol, a potent anti-angiogenesis agent, in combination with radiotherapy produces a synergistic antitumor efficacy without increasing toxicity

Hu J, Chen LJ, Liu L, Chen X, Chen PL, Yang G, Hou WL, Tang MH, Zhang F, Wang XH, Zhao X, Wei YQ

Honokiol is an active compound purified from magnolia that has been shown to induce cell differentiation, apoptosis, and anti-angiogenesis effects, as well as an enhancement in tumor growth delay in...
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Suppression of hepatic tumor growth and metastasis by metronomic therapy in a rat model of hepatocellular carcinoma

Jang JW, Park ST, Kwon JH, You CR, Choi JY, Jung CK, Bae SH, Yoon SK

Although continuous low-dose (metronomic [MET]) therapy exerts anti-cancer efficacy in various cancer models, the effect of long-term MET therapy for hepatocellular carcinoma (HCC) remains unknown. This study assessed the long-term...
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Phase II study of cyclophosphamide, doxorubicin, and vincristine (CAV) and etoposide plus cisplatin (EP) alternating chemotherapy combined with radiotherapy in small cell lung cancer

Park YJ, Koh EH, Kim J, Roh JK, Chang J, Ahn CM, Sohn HY, Kim SK, Lee WY, Kim K, Suh CO, Kim GE, Loh JJ, Kim BS

The development of drug resistance is the major limiting factor influencing the survival of patients with small cell lung cancer (SCLC). We have thus examined the activity of cyclophosphamide, doxorubicin...
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EGF Induced RET Inhibitor Resistance in CCDC6-RET Lung Cancer Cells

Chang H, Sung JH, Moon SU, Kim HS, Kim JW, Lee JS

PURPOSE: Rearrangement of the proto-oncogene rearranged during transfection (RET) has been newly identified potential driver mutation in lung adenocarcinoma. Clinically available tyrosine kinase inhibitors (TKIs) target RET kinase activity, which...
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Thalidomide for Treating Metastatic Hepatocellular Carcinoma: A Pilot Study

Han SH, Park SH, Kim JH, Lee JJ, Kwon SY, Kwon OS, Kim SS, Kim JH, Kim KK, Park YH, Lee JN, Nam E, Bang SM, Cho EK, Shin DB, Lee JH

BACKGROUND: Thalidomide has been reported to have antitumor activity for treating metastatic hepatocellular carcinoma (HCC). We evaluated the safety and efficacy of using thalidomide for treating selected patients with...
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Stenting of the Superior Vena Cava and Left Brachiocephalic Vein with Preserving the Central Venous Catheter in Situ

Isfort P, Penzkofer , Goerg F, Mahnken AH

Stenting of the central veins is well established for treating localized venous stenosis. The techniques regarding catheter preservation for central venous catheters in the superior vena cava have been described....
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