- Network pharmacology and molecular docking reveal the mechanism of Qinghua Xiaoyong Formula in Crohn’s disease
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Fang C, Pei Y, Peng Y, Lu H, Qu Y, Luo C, Lu Y, Yang W
- KMID: 2544138
- Korean J Physiol Pharmacol.
- 2023 Jul;27(4):365-374.
- doi: 10.4196/kjpp.2023.27.4.365
Crohn's disease (CD) is a chronic inflammatory illness of the digestive system with unknown etiology, and its incidence is increasing worldwide. However, there are currently no effective treatments or medications... -
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- Colonic Transit Disorder Mediated by Downregulation of Interstitial Cells of Cajal/Anoctamin-1 in Dextran Sodium Sulfate-induced Colitis Mice
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Lu C, Lu H, Huang X, Liu S, Zang J, Li Y, Chen J, Xu W
- KMID: 2449103
- J Neurogastroenterol Motil.
- 2019 Apr;25(2):316-331.
- doi: 10.5056/jnm18173
BACKGROUND/AIMS: Interstitial cells of Cajal (ICC) and their special calcium-activated chloride channel, anoctamin-1 (ANO1) play pivotal roles in regulating colonic transit. This study is designed to investigate the role of... -
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- Experimental infection of Paragonimus westermani in mice and rats
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Fan PC, Lu H, Lin LH
- KMID: 1715477
- Korean J Parasitol.
- 1993 Jun;31(2):91-97.
- doi: 10.3347/kjp.1993.31.2.91
To determine the infectivity and maturity of metacercariae of Paragonimus westermani after keeping at low temperature for a long period, 45 mice and 45 rats were each infected with 20... -
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- Advances in the Development of Anti-Adhesive Biomaterials for Tendon Repair Treatment
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Zhou H, Lu H
- KMID: 2512634
- Tissue Eng Regen Med.
- 2021 Feb;18(1):1-14.
- doi: 10.1007/s13770-020-00300-5
BACKGROUND: Peritendinous adhesion that simultaneous with tendon healing link the healing tendon to the surrounding tissue. It results in functional disability, and has a significant adverse impact on health as... -
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- Effect of bisphosphonates on the crystallization of stone-forming salts in synthetic urine
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Kovacevic , Lu H, Kovacevic , Lakshmanan Y
- KMID: 2500586
- Investig Clin Urol.
- 2020 May;61(3):310-315.
- doi: 10.4111/icu.2020.61.3.310
Purpose: We investigated the inhibitory effect of bisphosphonates (BPs) on the crystallization of calcium oxalate monohydrate (COM), calcium phosphate (CaP), and magnesium ammonium phosphate (MAP) in synthetic urine, aiming to... -
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- Body water percentage from childhood to old age
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Lu H, Ayers E, Patel P, Mattoo TK
- KMID: 2543788
- Kidney Res Clin Pract.
- 2023 May;42(3):340-348.
- doi: 10.23876/j.krcp.22.062
Background: Total body water (TBW) increases with growth, but the body water percentage (TBW%) decreases with aging. The objective of our study was to delineate TBW% in males and females... -
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- Complex dental anomalies in a belatedly diagnosed cleidocranial dysplasia patient
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Lu H, Zeng B, Yu D, Jing X, Hu B, Zhao W, Wang Y
- KMID: 2045027
- Imaging Sci Dent.
- 2015 Sep;45(3):187-192.
- doi: 10.5624/isd.2015.45.3.187
Cleidocranial dysplasia (CCD) is a rare congenital disorder, typically characterized by persistently open skull sutures, aplastic or hypoplastic clavicles, and supernumerary teeth. Mutations in the gene encoding the runt-related transcription... -
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- Cortical Morphometric Abnormality and Its Association with Working Memory in Children with Attention-Deficit/Hyperactivity Disorder
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Si FF, Liu L, Li HM, Sun L, Cao QJ, Lu H, Wang YF, Qian QJ
- KMID: 2518585
- Psychiatry Investig.
- 2021 Jul;18(7):679-687.
- doi: 10.30773/pi.2020.0333
Objective Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental disorder in children and adolescents. The present study investigated the cortical morphology features and their relationship with working memory (WM). Methods In the... -
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- Relationship of the maxillary posterior teeth and maxillary sinus floor in different skeletal growth patterns: A cone-beam computed tomographic study of 1600 roots
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Shrestha B, Shrestha R, Lu H, Mai Z, Chen L, Chen Z, Ai H
- KMID: 2527659
- Imaging Sci Dent.
- 2022 Mar;52(1):19-25.
- doi: 10.5624/isd.20210145
Purpose This study evaluated the distance from the posterior root apices to the maxillary sinus floor (MSF) and the frequency of roots touching or protruding through the MSF using cone-beam computed... -
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- Specific Mutations in APC, with Prognostic Implications in Metastatic Colorectal Cancer
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Peng H, Ying J, Zang J, Lu H, Zhao X, Yang P, Wang X, Li J, Gong Z, Zhang D, Wang Z
- KMID: 2547801
- Cancer Res Treat.
- 2023 Oct;55(4):1270-1280.
- doi: 10.4143/crt.2023.415
Purpose Loss-of-function mutations in the adenomatous polyposis coli (APC) gene are common in metastatic colorectal cancer (mCRC). However, the characteristic of APC specific mutations in mCRC is poorly understood. Here,... -
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- Management Strategy for Congenital Choledochal Cyst with Co-existing Intrahepatic Dilation and Aberrant Bile Duct As Well As Other Complicated Biliary Anomalies
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Dong Q, Jiang B, Zhang H, Jiang Z, Lu H, Yang C, Cheng Y, Hao X
- KMID: 1777172
- Yonsei Med J.
- 2006 Dec;47(6):826-832.
- doi: 10.3349/ymj.2006.47.6.826
The purpose of this study was to investigate and discuss imaging methods and management strategies for congenital choledochal cyst with co-existing intrahepatic dilation and aberrant bile duct as well as... -
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- Inhibition of miR-146a-5p and miR-8114 in Insulin-Secreting Cells Contributes to the Protection of Melatonin against Stearic Acid-Induced Cellular Senescence by Targeting Mafa
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Su S, Zhao Q, Dan L, Lin Y, Li X, Zhang Y, Yang C, Dong Y, Li X, Regazzi R, Sun C, Chu X, Lu H
- KMID: 2537291
- Endocrinol Metab.
- 2022 Dec;37(6):901-917.
- doi: 10.3803/EnM.2022.1565
Background: Chronic exposure to elevated levels of saturated fatty acids results in pancreatic β-cell senescence. However, targets and effective agents for preventing stearic acid-induced β-cell senescence are still lacking. Although... -
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- Chronic stress enhances progression of periodontitis via alpha1-adrenergic signaling: a potential target for periodontal disease therapy
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Lu H, Xu M, Wang F, Liu S, Gu J, Lin S
- KMID: 2155383
- Exp Mol Med.
- 2014 Oct;46(10):e118.
- doi: 10.1038/emm.2014.65
This study assessed the roles of chronic stress (CS) in the stimulation of the sympathetic nervous system and explored the underlying mechanisms of periodontitis. Using an animal model of periodontitis... -
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- Chronic stress accelerates ligature-induced periodontitis by suppressing glucocorticoid receptor-α signaling
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Lu H, Xu M, Wang F, Liu S, Gu J, Lin S, Zhao L
- KMID: 2361510
- Exp Mol Med.
- 2016 Mar;48(3):e223.
- doi: 10.1038/emm.2015.127
Periodontitis is a common chronic inflammatory disease. Recent studies have shown that chronic stress (CS) might modulate periodontal disease, but there are few models of CS-induced periodontitis, and the underlying... -
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- Colonic Dysmotility in Murine Partial Colonic Obstruction Due to Functional Changes in Interstitial Cells
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Wang Q, Zang J, Huang X, Lu H, Xu W, Chen J
- KMID: 2460488
- J Neurogastroenterol Motil.
- 2019 Oct;25(4):589-601.
- doi: 10.5056/jnm19136
BACKGROUND/AIMS: Interstitial cells play important roles in gastrointestinal (GI) neuro-smooth muscle transmission. The underlying mechanisms of colonic dysmotility have not been well illustrated. We established a partial colon obstruction (PCO)... -
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