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Hepatic computed tomography changes caused by amiodarone

Kenzaka T

No abstract available.
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The Effects of Korean Red Ginseng (Ginseng Radix Rubra) on Liver Regeneration after Partial Hepatectomy in Dogs

Kwon YS, Jang KH, Jang IH

  • KMID: 1099826
  • J Vet Sci.
  • 2003 Apr;4(1):83-92.
We investigated the effects of the oral administration of Korean red ginseng (KRG) on morphologic change and function of liver in dogs. Fifteen adult mongrel dogs (n=15) were divided into...
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A Case of Acute Pancreatitis and Acute Hepatitis Caused by Ingestion of Ceramium kondoi

Kim DB, Cho YK, Song HJ, Song BC

In Korea, the use of herbal remedies is a common cause of drug-induced liver injury. However, the occurrence of both acute pancreatitis and acute hepatitis after taking herbal remedies has...
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Rapid uptake of oxidized ascorbate induces loss of cellular glutathione and oxidative stress in liver slices

Song JH, Simons C, Cao L, Shin SH, Hong M, Chung IM

  • KMID: 1097253
  • Exp Mol Med.
  • 2003 Apr;35(2):67-75.
The observation that ascorbate known to retain pro-oxidant properties induces cell death in a number of immortal cell lines, led us to examine its mechanism and whether it is involved...
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Bisphenol A Impairs Mitochondrial Function in the Liver at Doses below the No Observed Adverse Effect Level

Moon MK, Kim MJ, Jung IK, Koo YD, Ann HY, Lee KJ, Kim SH, Yoon YC, Cho BJ, Park KS, Jang HC, Park YJ

Bisphenol A (BPA) has been reported to possess hepatic toxicity. We investigated the hypothesis that BPA, below the no observed adverse effect level (NOAEL), can induce hepatic damage and mitochondrial...
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Changes in expression of cell cycle regulators after G1 progression upon repetitive thioacetamide treatment in rat liver

Hong SH, Lee GD, Chung JY, Cho KS, Park SH, Kim IH, Jeong JS

  • KMID: 755208
  • Exp Mol Med.
  • 2002 Nov;34(5):361-366.
Repetitive low dose thioacetamide (TA) treatment of hepatocytes was found to induce cells in G2 arrest. In the present study, an attempt was made to investigate alterations in expression of...
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Development of altered hepatocyte foci by separate and combined treatments with radiation and diethylnitrosamine in neonatal rats

Kim SH, Lee YS, Lee MS, Kim TH, Jang JJ

To establish an in vivo radiation carcinogenesis model using glutathione S-transferase placental form positive (GST-P+) hepatic foci, newborn rats were irradiated once by 0.5 Gy and 2 Gy of gamma...
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Effects of Chronic Aluminum Administration on Blood and Liver Iron-Related Parameters in Mice

Turgut G, Kaptanoglu B, Turgut S, Enli Y, Genc O

In this study, the effects of chronically administered aluminum on iron metabolism-related parameters of liver and blood of mice were investigated. An additional purpose to determine how chronic aluminum administration...
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Betulinic acid prevents alcohol-induced liver damage by improving the antioxidant system in mice

Yi J, Xia W, Wu J, Yuan L, Wu J, Tu D, Fang J, Tan Z

Betulinic acid (BA), a pentacyclic lupane-type triterpene, has a wide range of bioactivities. The main objective of this work was to evaluate the hepatoprotective activity of BA and the potential...
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Phytotherapeutic effects of Echinacea purpurea in gamma-irradiated mice

Abouelella AM, Shahein YE, Tawfik SS, Zahran AM

Echinacea (E.) purpurea herb is commonly known as the purple coneflower, red sunflower and rudbeckia. In this paper, we report the curative efficacy of an Echinacea extract in gamma-irradiated mice....
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Grape extracts suppress the formation of preneoplastic foci and activity of fatty acid synthase in rat liver

Kweon S, Kim Y, Choi H

  • KMID: 1093609
  • Exp Mol Med.
  • 2003 Oct;35(5):371-378.
This study was conducted to examine the effects of dietary grape extracts on preneoplastic foci formation in rat hepatocarcinogenesis, and related hepatic enzymes. Male Sprague-Dawley rats were fed basal diet...
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Omega-3 polyunsaturated fatty acid and ursodeoxycholic acid have an additive effect in attenuating diet-induced nonalcoholic steatohepatitis in mice

Kim JK, Lee KS, Lee DK, Lee SY, Chang HY, Choi J, Lee JI

Nonalcoholic steatohepatitis (NASH) can progress into liver cirrhosis; however, no definite treatment is available. Omega-3 polyunsaturated fatty acid (omega-3) has been reported to alleviate experimental NASH, although its beneficial effect...
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Antifibrotic effects of magnesium lithospermate B on hepatic stellate cells and thioacetamide-induced cirrhotic rats

Paik YH, Yoon YJ, Lee HC, Jung MK, Kang SH, Chung SI, Kim JK, Cho JY, Lee KS, Han KH

Magnesium lithospermate B (MLB) is one of the major active components of Salvia miltiorrhizae. The anti-oxidative effects of Salvia miltiorrhizae have been previously reported. The aim of this study was...
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Combined Radiofrequency Ablation and Acetic Acid Hypertonic Saline Solution Instillation: An In Vivo Study of Rabbit Liver

Lee JM, Kim YK, Kim SW, Han JK, Kim SH, Choi BI

OBJECTIVE: We wanted to determine whether combined radiofrequency ablation (RFA) and acetic acid-hypertonic saline solution (AHS) instillation can increase the extent of thermally mediated coagulation in in vivo rabbit liver...
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Effects of D-002, a mixture of high molecular weight beeswax alcohols, on patients with nonalcoholic fatty liver disease

Illnait J, Rodriguez , Mendoza S, Fernandez , Mas R, Miranda M, Pinera J, Fernandez , Mesa M, Fernandez , Carbajal D, Gamez R

BACKGROUND/AIMS: Nonalcoholic fatty liver disease (NAFLD) is intimately related to insulin resistance and ranges from a benign course to liver fibrosis and cirrhosis. NAFLD management mainly involves dietary modification and...
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SPA0355 attenuates ischemia/reperfusion-induced liver injury in mice

Bae UJ, Yang JD, Ka SO, Koo JH, Woo SJ, Lee YR, Yu HC, Cho BH, Zhao HY, Ryu JH, Lee SM, Jeon R, Park BH

Hepatic ischemia/reperfusion (I/R) injury leads to oxidative stress and acute inflammatory responses that cause liver damage and have a considerable impact on the postoperative outcome. Much research has been performed...
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Induction of apoptotic lesions in liver and lymphoid tissues and modulation of cytokine mRNA expression by acute exposure to deoxynivalenol in piglets

Mikami O, Yamaguchi , Murata H, Nakajima Y, Miyazaki S

Six 1-month-old piglets were intravenously injected with deoxynivalenol (DON) at the concentration of 1 mg/kg body weight, with three pigs each necropsied at 6 and 24 h post-injection (PI) for...
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Aristolochia manshuriensis Kom ethyl acetate extract protects against high-fat diet-induced non-alcoholic steatohepatitis by regulating kinase phosphorylation in mouse

Kwak DH, Kim JS, Chang KT, Choo YK

Aristolochia manshuriensis Kom (AMK) is an herb used as a traditional medicine; however, it causes side effects such as nephrotoxicity and carcinogenicity. Nevertheless, AMK can be applied in specific ways...
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Physical Activity- and Alcohol-dependent Association Between Air Pollution Exposure and Elevated Liver Enzyme Levels: An Elderly Panel Study

Kim KN, Lee H, Kim JH, Jung K, Lim YH, Hong YC

OBJECTIVES: The deleterious effects of air pollution on various health outcomes have been demonstrated. However, few studies have examined the effects of air pollution on liver enzyme levels. METHODS: Blood samples...
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Expression of G1 Cell Cycle Regulators in Rat Liver upon Repeated Exposure to Thioacetamide

Kim KT, Han SY, Jeong JS

  • KMID: 760708
  • Korean J Hepatol.
  • 2007 Mar;13(1):81-90.
BACKGROUND/AIMS: Eukaryotic cell cycle is regulated by signal transduction pathways mediated by complexes of cyclin dependent kinases (CDKs) and their partner cyclins, or by interaction with CDK inhibitors. Thioacetamide...
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