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Clinical Characteristics of Dementia with Lewy Bodies

Cheon JS, Chiu E

  • KMID: 2064042
  • J Korean Geriatr Psychiatry.
  • 2001 Jun;5(1):36-46.
The dementia with Lewy bodies which was common next to the Alzheimer's dementia had been oftenly misdiagnozed as vascular dementia. The pathologic diagnosis of dementia with Lewy bodies was increasing...
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Dementia With Lewy Bodies Diagnosed by Cognitive Fluctuation After Anticholinergic Medication

Ku BD, Yoo HU

  • KMID: 2185072
  • J Korean Neurol Assoc.
  • 2008 Aug;26(3):254-258.
Dementia with Lewy bodies (DLB) usually presents with progressive cognitive decline and parkinsonism. We report a 68-year-old man who showed parkinsonism including resting tremor and mild cognitive decline. After anticholinergic...
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Potential Role of the Sigma-1 Receptor Chaperone in the Beneficial Effects of Donepezil in Dementia with Lewy Bodies

Hashimoto

  • KMID: 2171197
  • Clin Psychopharmacol Neurosci.
  • 2013 Apr;11(1):43-44.
No abstract available.
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Diagnosis and Management of Dementia with Lewy Bodies

Kim TH

  • KMID: 2137454
  • J Korean Geriatr Psychiatry.
  • 2012 Dec;16(2):75-81.
Dementia with Lewy bodies (DLB) is considered the second most common cause of neurodegenerative dementia. It is characterized with clinical and pathological feature that distinguish it from Alzheimer's disease (AD)....
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Topographical Propagation of alpha-synuclein Pathology in Parkinson's Disease: Phenomenology and Hypothetical Mechanism

Hyun M, Lee SJ

Parkinson's disease is an age-related, slowly progressing neurodegenerative disorder characterized by abnormal deposition of aggregated alpha-synuclein in neuronal cell bodies (Lewy bodies) and neurites (Lewy neurites), as well as in...
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Dementia with Lewy Bodies

Kim SG, Jung HY

  • KMID: 2334057
  • J Korean Geriatr Psychiatry.
  • 2007 Dec;11(2):62-72.
Here the author reviews the clinical and pathologic characteristics of dementia with Lewy bodies (DLB). DLB took many years to crystallize into a recognizable clinico-pathologic entity. Based on sensitive immunostaining...
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Clinical Features and Pharmacological Treatment of Dementia with Lewy Bodies

Kim TH

Dementia with Lewy bodies (DLB) is the second most common causes of dementia. It can exhibit a variety of clinical symptoms including cognitive decline, cognitive fluctuation, visual hallucinations, parkinsonism, REM...
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¹²³I-Meta-iodobenzylguanidine Sympathetic Imaging: Standardization and Application to Neurological Diseases

Nakajima K, Yamada M

¹²³I-meta-iodobenzylguanidine (MIBG) has become widely applied in Japan since its introduction to clinical cardiology and neurology practice in the 1990s. Neurological studies found decreased cardiac uptake of ¹²³I-MIBG in Lewy-body...
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PET studies in Alzheimer Disease and Other Degenerative Dementias

Jeong Y, Na DL

  • KMID: 1516895
  • Korean J Nucl Med.
  • 2003 Feb;37(1):13-23.
Neurodegenerative disorders cause a variety of dementia including Alzheimer disease, frontotemporal dementia, dementia with Lewy bodies, corticobasal degeneration, progressive supranuclear palsy, and Huntington's disease. PET scan is useful for early...
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Improvement of Visuo-spatial Function Assessed by Raven’s Colored Progressive Matrices in Dementia with Lewy Bodies by Donepezil Treatment

Yoshino Y, Mori T, Yoshida T, Toyota Y, Shimizu H, Iga JI, Nishitani , Ueno SI

OBJECTIVE: Donepezil is used to improve cognitive impairment of dementia with Lewy bodies (DLB). Visuo-spatial dysfunction is a well-known symptom of DLB. Non-verbal Raven’s Colored Progressive Matrices (RCPM) were used...
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A Case of Probable Diffuse Lewy Body Dementia

Cheon JS, Yoon H

  • KMID: 2137470
  • J Korean Geriatr Psychiatry.
  • 2000 Dec;4(2):199-206.
A case of Lewy body dementia in a 71 year-old male patient was reported and related articles were also reviewed. He has been ill with Parkinsonism since 1988, and referred to...
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Neuropsychological Assessment of Dementia with Lewy Bodies: Comparison with Alzheimer's Disease: A Preliminary Study

Park KW, Kim JW

  • KMID: 2195073
  • J Korean Neurol Assoc.
  • 2003 Jun;21(3):267-272.
BACKGROUND: Dementia with Lewy bodies (DLB) is now considered to be the second most common pathological cause of dementia after Alzheimer's dementia (AD). Little has been known about differences in...
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Diagnosis and Clinical Progress in a Case of Dementia with Lewy Bodies

Lee SS, Kim MJ

Dementia with Lewy bodies(DLB) is the second most common neurodegenerative disease. However, DLB might not be adequately diagnosed due to its variety of clinical symptoms. The authors present 65-year-old Mrs....
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Alpha-Synuclein Function and Dysfunction on Cellular Membranes

Snead D, Eliezer D

Alpha-synuclein is a small neuronal protein that is closely associated with the etiology of Parkinson's disease. Mutations in and alterations in expression levels of alpha-synuclein cause autosomal dominant early onset...
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Amyloidogenic Protein of alpha-Synuclein

Yang JE, Paik SR

Amyloidogenesis is the key pathological phenomenon commonly observed in various neurodegenerative disorders. alpha-Synuclein is the major constituent of Lewy bodies as a common pathological signature of Lewy body diseases (LBDs)...
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Structure, Distribution, and Genetic Profile of α-Synuclein and Their Potential Clinical Application in Parkinson's Disease

Si X, Pu J, Zhang B

Parkinson's disease (PD), the second most common neurodegenerative disorder after Alzheimer's disease, is characterized by the loss of nigral dopaminergic neurons. PD leads to a series of clinical symptoms, including...
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Inclusion Body Formation and Apoptotic Cell Death in the Human Neural Stem Cells HB1.F3 Following Gene Transfection of Alpha-Synuclein and Synphilin-1

Cheon SM, Lee G, Kim JW, Kim SU

  • KMID: 2343254
  • J Korean Neurol Assoc.
  • 2007 Aug;25(3):344-352.
BACKGROUND: The etiology of Parkinson's disease (PD) has not been established, but familial forms of the disease have some clues for its pathogenesis. Autosomal dominantly inherited familial PD induced by...
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FDG PET Imaging For Dementia

Ahn BC

  • KMID: 2313030
  • Nucl Med Mol Imaging.
  • 2007 Apr;41(2):102-111.
Dementia is a major burden for many countries including South Korea, where life expectancy is continuously growing and the proportion of aged people is rapidly growing. Neurodegenerative disorders, such as,...
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Dementia with Lewy Bodies versus Alzheimer's Disease and Parkinson's Disease Dementia: A Comparison of Cognitive Profiles

Park KW, Kim HS, Cheon SM, Cha JK, Kim SH, Kim JW

BACKGROUND AND PURPOSE: It is particularly difficult to differentiate dementia with Lewy bodies (DLB) from the related dementias of Alzheimer's disease (AD) and Parkinson's disease dementia (PDD). Few studies have...
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Imaging Improves Diagnosis of Dementia with Lewy Bodies

Tateno M, Kobayashi , Saito T

  • KMID: 2315845
  • Psychiatry Investig.
  • 2009 Dec;6(4):233-240.
Dementia with Lewy bodies (DLB) is the second most common cause of degenerative dementia after Alzheimer's disease (AD), and is clinically characterized by the progressive cognitive decline with fluctuations in...
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