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Assessment of leukotriene E4 in exhaled breath condensate as a marker of inflammation and therapeutic effect in allergic rhinitis children

Kwak BO, Park YM

PURPOSE: Recent studies have shown that the cysteinyl leukotriene (cysLT) of exhaled breath condensate (EBC) could be predictive of inflammatory status and effectiveness of treatment in allergic disease. The aim...
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A Double-Blind, Randomized, Crossover Study to Compare the Effectiveness of Montelukast on Atopic Dermatitis in Korean Children

Jeon YH, Min TK, Yang HJ, Pyun BY

PURPOSE: Some studies report a role of leukotrienes in the pathogenesis of atopic dermatitis and suggest a rationale for the use of leukotriene receptor antagonist (LTRA) in the treatment of...
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Ratio of Leukotriene E4 to Exhaled Nitric Oxide and the Therapeutic Response in Children With Exercise-Induced Bronchoconstriction

Baek HS, Cho J, Kim JH, Oh JW, Lee HB

PURPOSE: This study assessed the association between the ratio of leukotriene E4 (LTE4) to fractional exhaled nitric oxide (FENO) in the response of children with exercise-induced bronchoconstriction (EIB) enrolled in...
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Association of SCORAD Index and Aeroallergen Sensitization on Urinary Leukotriene E4 in Children with Atopic Dermatitis

Shin SJ, Kim MJ, Jung MH, Jin HS, Han MK, Park KY, Oh MY, Kim BS

  • KMID: 2315277
  • Pediatr Allergy Respir Dis.
  • 2012 Sep;22(3):302-311.
PURPOSE: Atopic dermatitis (AD) is a genetically determined, chronic relapsing skin disease. The pathogenesis of AD is complex and the course is unpredictable. Atopy is an important risk factor for...
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Study of Urinary Leukotriene E4 and Eosinophil Cationic Protein in Nasopharyngeal Aspiration from Wheezing Infants

Kwon SJ, Koo BS, Lee HB, Oh JW

  • KMID: 2314309
  • Pediatr Allergy Respir Dis.
  • 2004 Mar;14(1):46-52.
PURPOSE: Although early detection of airway inflammation is important to enable early prevention and treatment, it is not easy to differentiate clinically between respiratory virus- induced bronchiolitis and infantile asthma...
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Correlation between the Level of Urinary Leukotriene E4 and Seurm Eosinophil Cationic Protein and Clinical Severity of Atopic Dermatitis in Children

  • KMID: 2234226
  • Korean J Asthma Allergy Clin Immunol.
  • 2004 Dec;24(4):409-414.
BACKGROUND: Atopic dermatitis is a chronic inflammatory relapsing skin disorder. It has been shown that urinary LTE4 and serum ECP level are elevated and correlated with disease activity. OBJECTIVE: We...
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Clinical application of urinary leukotriene E4 in bronchial asthma

Yoon HK, Shin Y, Lee SH, Lee SY, Kim SC, Kim KH, Moon HS, Song JS, Park SH

  • KMID: 2285928
  • J Asthma Allergy Clin Immunol.
  • 2001 Aug;21(4):600-609.
BACKGROUND: Cysteinyl leukotrienes are important inflammatory mediators in bronchial asthma because they enhance microvascular permeability, increase nonspecific bronchial hyperresponsiveness, and are potent bronchoconstrictor agents. Leukotriene E4 is a major metabolite...
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The Difference between the Concentrations of Arachidonic Acid Metabolites in the Cholesterol Granuloma and Granulation Tissues in Chronic Otitis Media

Jang YJ, Kim HG, Oh JK, Rhee CK

  • KMID: 1923255
  • Korean J Otolaryngol-Head Neck Surg.
  • 2001 May;44(5):466-469.
BACKGROUND AND OBJECTIVES: Both the granulation tissue and cholesterol granuloma can erode the surrounding bone and ossicles. However, the etiology of bone resorption in the granulation tissue and cholesterol granuloma...
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Urinary N-methylhistamine and sulfidopeptide leukotriene in exercise-induced asthma

Park JK, Bahn JW, Lee BJ, Son JW, Lee SR, Kim YK, Cho SH, Min KU, Kim YY

  • KMID: 2286172
  • J Asthma Allergy Clin Immunol.
  • 1998 Mar;18(1):40-51.
BACKGROUND: Exercise can aggravate asthmatic symptoms in many patients with bronchial asthma. It is caused by that inhaled air bypasses nasal cavity and goes directly to the lower airways through open mouth...
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Effects of Substance P on Histamine and Leukotriene E4 Release from Rat Mast Cells according to Temperature Changes

Kim YB, Park MS, Lim HJ, Cho JS, Cha CI

  • KMID: 1922547
  • Korean J Otolaryngol-Head Neck Surg.
  • 1997 Apr;40(4):580-588.
It has been widely known that nasal mucosa shows reaction to neuromediators, to irritants, and to physical stimuli such as cold exposure. The mechanisms of hypersensitivity to cold were not...
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