- Prognostic Effect of cytoplasmic CD79a Expression in Acute Myeloid Leukemia with t(8;21)
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Chung HJ, Chi HS, Cho YU, Lee EH, Jang S, Park CJ, Seo EJ
- KMID: 1781541
- Korean J Lab Med.
- 2007 Dec;27(6):388-393.
- doi: 10.3343/kjlm.2007.27.6.388
BACKGROUND: Although cytoplasmic CD79a (cytCD79a) is a highly lineage-specific marker of B lymphoid cells and plays an important role in the diagnosis of acute leukemia, its clinical significance is... -
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- Spectra of Chromosomal Aberrations in 325 Leukemia Patients and Implications for the Development of New Molecular Detection Systems
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Choi HJ, Kim HR, Shin MG, Kook H, Kim HJ, Shin JH, Suh SP, Ryang DW
- KMID: 1094259
- J Korean Med Sci.
- 2011 Jul;26(7):886-892.
- doi: 10.3346/jkms.2011.26.7.886
This study investigated the spectrum of chromosomal abnormalities in 325 leukemia patients and developed optimal profiles of leukemic fusion genes for multiplex RT-PCR. We prospectively analyzed blood and bone marrow... -
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- Two Cases of Acute Myeloid Leukemia with t(16;21)(p11;q22) and TLS/FUS-ERG Fusion Transcripts
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Chang WR, Park IJ, Lee HW, Park JS, Kim HC, Kim HJ, Han JH, Cho SR
- KMID: 1077413
- Korean J Lab Med.
- 2009 Oct;29(5):390-395.
- doi: 10.3343/kjlm.2009.29.5.390
Many AML-associated chromosomal abnormalities, such as t(8;21), t(15;17), inv(16), t(9;11), t(9;22) and t(6;9) are well known. The chromosomal aberration of t(16;21)(p11;q22) in AML is rare and it is known to... -
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- A Case of del(16)(q22) in a Patient with Acute Myeloid Leukemia with Complex Karyotype
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Kim M, Lee JW, Lee JK, Hong YJ, Hong SI, Kang HJ, Cho EH, Chang YH
- KMID: 1781636
- Korean J Lab Med.
- 2010 Aug;30(4):329-333.
- doi: 10.3343/kjlm.2010.30.4.329
Inversion of chromosome 16 [inv(16)(p13.1q22)] and t(16;16)(p13.1;q22) are associated with acute myelomonocytic leukemia (AMML) with eosinophilia and a favorable prognosis. On the other hand, patients with del(16)(q22) usually present with... -
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- Distribution of Antigenic Aberration in the Bone Marrow of Acute Leukemia in Complete Remission
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Shin S, Kahng J, Kim M, Lim J, Kim Y, Han K
- KMID: 1781552
- Korean J Lab Med.
- 2008 Feb;28(1):1-7.
- doi: 10.3343/kjlm.2008.28.1.1
BACKGROUND: The aberrant, leukemia-associated antigen expression patterns allow us to discriminate leukemic blasts from normal precursor cells. Our major goal was to determine a guideline for the detection of minimal... -
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- Clathrin Assembly Lymphoid Myeloid Leukemia-AF10-positive Acute Leukemias: A Report of 2 Cases with a Review of the Literature
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Huh JY, Chung S, Oh D, Kang MS, Eom HS, Cho EH, Han MH, Kong SY
- KMID: 1096795
- Korean J Lab Med.
- 2010 Apr;30(2):117-121.
- doi: 10.3343/kjlm.2010.30.2.117
The translocation t(10;11)(p13;q14q21) has been found to be recurrent in acute lymphoblastic and myeloid leukemias, and results in the fusion of the clathrin assembly lymphoid myeloid leukemia (CALM) gene with... -
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- Minor BCR-ABL1-Positive Acute Myeloid Leukemia Associated With the NPM1 Mutation and FLT3 Internal Tandem Duplication
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Kim MJ, Ahn S, Jeong SH, Jang JH, Han JH, Choi JR, Cho SR
- KMID: 2373538
- Ann Lab Med.
- 2016 May;36(3):263-265.
- doi: 10.3343/alm.2016.36.3.263
No abstract available. -
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- Diagnostic Utility of Multiprobe Fluorescence in situ Hybridization Assay for Detecting Cytogenetic Aberrations in Acute Leukemia
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Kim BR, Choi JL, Kim JE, Woo KS, Kim KH, Kim JM, Kim SH, Han JY
- KMID: 1791920
- Ann Lab Med.
- 2014 May;34(3):198-202.
- doi: 10.3343/alm.2014.34.3.198
BACKGROUND: Specific cytogenetic aberrations detected by conventional karyotyping or FISH play a major role in the diagnosis, prognosis, and treatment of patients with acute leukemia. The FISH technique enhances the... -
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- Relationship between In Vitro Chemosensitivity assessed with MTT Assay and Clinical Outcomes in 103 Patients with Acute Leukemia
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Jun KR, Jang S, Chi HS, Lee KH, Lee JH, Choi SJ, Seo JJ, Moon HN, Im HJ, Park CJ
- KMID: 1781465
- Korean J Lab Med.
- 2007 Apr;27(2):89-95.
- doi: 10.3343/kjlm.2007.27.2.89
BACKGROUND: Cellular drug resistance is supposed to play a major role in chemotherapy failure or relapse. The purpose of this study was to analyze the relationship between in vitro... -
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- The Utility of the Multiplex Reverse Transcriptase-Polymerase Chain Reaction Assay in the Detection of Hematologic Malignancies
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Kim MJ, Cho SY, Lee WI, Park TS, Lee HJ
- KMID: 1707242
- Ann Lab Med.
- 2013 Jul;33(4):304-307.
- doi: 10.3343/alm.2013.33.4.304
No abstract available. -
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- Constitutional Pericentric Inversion 9 in Korean Patients with Chronic Myelogenous Leukemia
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Suh B, Song J, Kim J, Park TS, Choi JR
- KMID: 1781618
- Korean J Lab Med.
- 2010 Jun;30(3):218-223.
- doi: 10.3343/kjlm.2010.30.3.218
BACKGROUND: Although the pericentric inversion of chromosome 9, inv(9)(p11q13), is generally considered a normal variation, it is also associated with solid tumors and several hematologic malignancies such as biphenotypic acute... -
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- Characteristics and Outcomes of Second Malignant Neoplasms after Childhood Cancer Treatment: Multi-Center Retrospective Survey
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Koh KN, Yoo KH, Im HJ, Sung KW, Koo HH, Kim HS, Han JW, Yoon JH, Park HJ, Park BK, Baek HJ, Kook H, Lee JA, Lee JM, Lee KC, Kim SK, Park M, Lee YH, Lyu CJ, Seo JJ
- KMID: 2373753
- J Korean Med Sci.
- 2016 Aug;31(8):1254-1261.
- doi: 10.3346/jkms.2016.31.8.1254
This retrospective study investigated the clinical characteristics and outcomes of second malignant neoplasms (SMNs) in survivors of childhood cancer from multiple institutions in Korea. A total of 102 patients from... -
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- CD4+CD25highFoxP3+ Regulatory T-cells in Hematologic Diseases
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Moon HW, Kim BH, Park CM, Hur M, Yun YM, Kim SY, Lee MH
- KMID: 1781685
- Korean J Lab Med.
- 2011 Oct;31(4):231-237.
- doi: 10.3343/kjlm.2011.31.4.231
BACKGROUND: CD4+CD25+ regulatory T-cells (Tregs) play a critical role in immune responses. We explored the status of Tregs in neoplastic and autoimmune hematologic diseases. We also evaluated the technical aspects... -
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